Drugs Used in Alcohol Dependence

Name
Drugs Used in Alcohol Dependence
Accession Number
DBCAT002441
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
AcamprosateA medication used to maintain alcohol abstinence in patients with alcohol dependence.
NaltrexoneA narcotic antagonist used in opioid overdose.
NalmefeneAn opioid antagonist used in conjunction with psychosocial support to help adults with alcohol dependence reduce alcohol consumption.
Calcium carbimideCalcium carbimide has not been approved by the FDA but the intended indication is for the treatment of alcoholism. This medication was marketed in Canada, United Kingdom and Europe under...
DisulfiramA carbamate derivative used to treat alcohol addiction.
Drugs & Drug Targets
DrugTargetType
AcamprosateMetabotropic glutamate receptor 5target
AcamprosateProton-coupled amino acid transporter 1transporter
AcamprosateGABA(A) Receptortarget
AcamprosateGlutamate (NMDA) receptortarget
NaltrexoneMu-type opioid receptortarget
NaltrexoneKappa-type opioid receptortarget
NaltrexoneDelta-type opioid receptortarget
NaltrexoneHCG20471, isoform CRA_ctarget
NaltrexoneUDP-glucuronosyltransferase 1-1enzyme
NalmefeneMu-type opioid receptortarget
NalmefeneKappa-type opioid receptortarget
NalmefeneDelta-type opioid receptortarget
NalmefeneUDP-glucuronosyltransferase 2B7enzyme
NalmefeneUDP-glucuronosyltransferase 1-3enzyme
NalmefeneUDP-glucuronosyltransferase 1-8enzyme
Calcium carbimideAldehyde dehydrogenase family 3 member B2target
Calcium carbimideCatalaseenzyme
DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DisulfiramCytochrome P450 2E1enzyme
DisulfiramDopamine beta-hydroxylasetarget
DisulfiramCytochrome P450 3A4enzyme
DisulfiramCytochrome P450 3A5enzyme
DisulfiramBile salt export pumptransporter