Drugs Used in Alcohol Dependence

DrugDrug NameDrug Indication
DB00659AcamprosateFor the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation
DB00704NaltrexoneUsed as an adjunct to a medically supervised behaviour modification program in the maintenance of opiate cessation in individuals who were formerly physically dependent on opiates and who have successfully undergone detoxification. Also used for the management of alcohol dependence in conjunction with a behavioural modification program.
DB06230NalmefeneIndicated for the reduction of alcohol consumption in adult patients with alcohol dependence who have a high drinking risk level (DRL), without physical withdrawal symptoms and who do not require immediate detoxification [L1024]. Indicated for the complete or partial reversal of opioid drug effects, including respiratory depression - induced by either natural or synthetic opioids - or in the management of known or suspected opioid overdose [FDA Label].
DB09116Calcium carbimideCalcium carbimide has not been approved by the FDA but the intended indication is for the treatment of alcoholism.[T74] This medication was marketed in Canada, United Kingdom and Europe under the trade name of Temposil for the sole use of alcoholism treatment.[L1114]