Nitrogen Binding Agent

DrugDrug NameDrug Description
DB03793Benzoic acidAn antimicrobial food additive.
DB06819Phenylbutyric acidAn agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy.
DB09269Phenylacetic acidAn agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle.
DB00936Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
DB09096Benzoyl peroxideAn antibacterial and anti-inflammatory agent used for the symptomatic treatment of mild to moderate acne vulgaris and rosacea.
DB08909Glycerol phenylbutyrateA nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions.
DrugDrug NameTargetType
DB03793Benzoic acidPeroxiredoxin-5, mitochondrialtarget
DB03793Benzoic acidHeat-labile enterotoxin B chaintarget
DB03793Benzoic acidCocaine esterasetarget
DB03793Benzoic acidHTH-type transcriptional regulator MalTtarget
DB03793Benzoic acidTautomerase PptAtarget
DB03793Benzoic acidD-amino-acid oxidasetarget
DB03793Benzoic acidRibonuclease UK114target
DB03793Benzoic acidChlorocatechol 1,2-dioxygenasetarget
DB03793Benzoic acidRas-related protein Rab-9Atarget
DB03793Benzoic acidHydrogen peroxide-inducible genes activatortarget
DB03793Benzoic acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03793Benzoic acidNon-heme chloroperoxidasetarget
DB03793Benzoic acidOxygen-insensitive NAD(P)H nitroreductasetarget
DB03793Benzoic acidHydroxyquinol 1,2-dioxygenasetarget
DB03793Benzoic acidReplication proteintarget
DB03793Benzoic acidSolute carrier organic anion transporter family member 2B1transporter
DB03793Benzoic acidSolute carrier family 22 member 8transporter
DB03793Benzoic acidMonocarboxylate transporter 1transporter
DB03793Benzoic acidSolute carrier family 15 member 1target
DB06819Phenylbutyric acidAromatic-amino-acid aminotransferasetarget
DB06819Phenylbutyric acidThermolysintarget
DB06819Phenylbutyric acidCytochrome P450 2D6enzyme
DB09269Phenylacetic acidLiver carboxylesterase 1enzyme
DB00936Salicylic acidSerum albumincarrier
DB00936Salicylic acidProstaglandin G/H synthase 1target
DB00936Salicylic acidProstaglandin G/H synthase 2target
DB00936Salicylic acidAldo-keto reductase family 1 member C1target
DB00936Salicylic acidSolute carrier family 22 member 6transporter
DB00936Salicylic acidSolute carrier family 22 member 10transporter
DB00936Salicylic acidSolute carrier family 22 member 8transporter
DB00936Salicylic acidSolute carrier family 22 member 11transporter
DB00936Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
DB00936Salicylic acidMonocarboxylate transporter 1transporter
DB00936Salicylic acidSolute carrier family 22 member 7transporter
DB00936Salicylic acidCytochrome P450 2C9enzyme
DB08909Glycerol phenylbutyratePancreatic triacylglycerol lipaseenzyme
DB08909Glycerol phenylbutyrateCytochrome P450 3A4enzyme
DB08909Glycerol phenylbutyrateCytochrome P450 2D6enzyme