Copper(II) dithiosemicarbazone
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Copper(II) dithiosemicarbazone
- DrugBank Accession Number
- DB16963
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental, Investigational
- Structure
- Weight
- Average: 321.91
Monoisotopic: 321.001735 - Chemical Formula
- C8H14CuN6S2
- Synonyms
- Atsm copper (ii)
- Copper, ((2,2'-(1,2-dimethyl-1,2-ethanediylidene)bis(n-methylhydrazinecarbothioamidato-.kappa.n2,.kappa.s))(2-))-, (sp-4-2)-
- Copper(ii) diacetyl-di(n4-methyl)thiosemicarbazone
- Cu-atsm
- Cu(ii)atsm
- Diacetyl(n(4)-methylthiosemicarbazonato) copper (ii)
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0YDK1H9L3A
- CAS number
- 68341-09-3
- InChI Key
- SBHDKYTVDCRMOE-JPAPVDFESA-L
- InChI
- InChI=1S/C8H16N6S2.Cu/c1-5(11-13-7(15)9-3)6(2)12-14-8(16)10-4;/h1-4H3,(H2,9,13,15)(H2,10,14,16);/q;+2/p-2/b11-5+,12-6+;
- IUPAC Name
- copper(2+) [(Z)-N-methyl-N'-[(E)-[(3E)-3-{[(Z)-[(methylamino)(sulfanidyl)methylidene]amino]imino}butan-2-ylidene]amino]carbamimidoyl]sulfanide
- SMILES
- [Cu++].CN\C([S-])=N\N=C(/C)\C(\C)=N\N=C(/[S-])NC
References
- General References
- Not Available
- External Links
- ChemSpider
- 7858896
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Completed Treatment Amyotrophic Lateral Sclerosis (ALS) 1 2, 3 Unknown Status Treatment Amyotrophic Lateral Sclerosis (ALS) 1 1 Completed Treatment Amyotrophic Lateral Sclerosis (ALS) / MND (Motor Neurone Disease) 1 1 Completed Treatment Parkinson's Disease (PD) 1 1, 2 Active Not Recruiting Treatment Amyotrophic Lateral Sclerosis (ALS) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.799 mg/mL ALOGPS logP 1.18 ALOGPS logP 1.12 Chemaxon logS -2.7 ALOGPS pKa (Strongest Acidic) 6.51 Chemaxon pKa (Strongest Basic) 4.1 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 73.5 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 73.32 m3·mol-1 Chemaxon Polarizability 27.22 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 15, 2022 01:45 / Updated at December 01, 2022 11:33