Active, Moderate to Severe Rheumatoid Arthritis
Also known as: Moderate to Severe Active Rheumatoid Arthritis / Active Moderate to Severe Rheumatoid Arthritis
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB14845 | Filgotinib | A Janus kinase (JAK) 1 selective inhibitor used to treat cases of rheumatoid arthritis that are unresponsive to conventional treatments. |
| DB00073 | Rituximab | A monoclonal anti-CD20 antibody used to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Wegener's granulomatosis, pemphigus vulgaris, and rheumatoid arthritis. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB14845 | Filgotinib | Tyrosine-protein kinase JAK1 | target |
| DB14845 | Filgotinib | Cocaine esterase | enzyme |
| DB14845 | Filgotinib | Liver carboxylesterase 1 | enzyme |
| DB14845 | Filgotinib | P-glycoprotein 1 | transporter |
| DB00073 | Rituximab | B-lymphocyte antigen CD20 | target |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB05611 | Apilimod | 2 | Completed | 1 |
| DB00563 | Methotrexate | 3 | Completed | 1 |
| DB06273 | Tocilizumab | 3 | Completed | 1 |
| DB08895 | Tofacitinib | Not Available | Recruiting | 1 |