Narcolepsy Without Cataplexy

Also known as: Narcolepsy without cataplexy (disorder) / Narcolepsy / Narcolepsy (disorder)

Drug	Drug Name	Drug Description
DB11642	Pitolisant	An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults.

Drug	Drug Name	Target	Type
DB11642	Pitolisant	Histamine H3 receptor	target
DB11642	Pitolisant	Cytochrome P450 3A4	enzyme
DB11642	Pitolisant	Cytochrome P450 2D6	enzyme
DB11642	Pitolisant	Cytochrome P450 1A2	enzyme
DB11642	Pitolisant	Cytochrome P450 2B6	enzyme
DB11642	Pitolisant	Solute carrier family 22 member 1	transporter
DB11642	Pitolisant	Potassium voltage-gated channel subfamily H member 2	target
DB11642	Pitolisant	Serum albumin	carrier
DB11642	Pitolisant	Alpha-1-acid glycoprotein 1	carrier

Drug	Drug Name	Phase	Status	Count
DB01205	Flumazenil	1 / 2	Completed	1
DB00182	Amphetamine	2	Completed	1
DB01211	Clarithromycin	2	Recruiting	1
DB01576	Dextroamphetamine	2	Completed	1
DB00579	Mazindol	2	Completed	1
DB00745	Modafinil	2	Completed	1
DB11642	Pitolisant	3	Active Not Recruiting	1
DB11642	Pitolisant	Not Available	No Longer Available	1