High affinity copper uptake protein 1
Details
- Name
- High affinity copper uptake protein 1
- Synonyms
- Copper transporter 1
- COPT1
- CTR1
- hCTR1
- Solute carrier family 31 member 1
- Gene Name
- SLC31A1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0017175|High affinity copper uptake protein 1 MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSG LVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETH KTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKA VVVDITEHCH
- Number of residues
- 190
- Molecular Weight
- 21090.545
- Theoretical pI
- 7.47
- GO Classification
- Functionscopper ion transmembrane transporter activity / copper uptake transmembrane transporter activityProcessescellular copper ion homeostasis / cellular response to cisplatin / copper ion import into cell / copper ion transport / drug transmembrane transport / transmembrane transportComponentsintegral component of plasma membrane / late endosome / neuronal cell body / plasma membrane / recycling endosome
- General Function
- Copper uptake transmembrane transporter activity
- Specific Function
- High-affinity, saturable copper transporter involved in dietary copper uptake.
- Pfam Domain Function
- Ctr (PF04145)
- Transmembrane Regions
- 62-82 133-153 157-177
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0017176|High affinity copper uptake protein 1 (SLC31A1) ATGGATCATTCCCACCATATGGGGATGAGCTATATGGACTCCAACAGTACCATGCAACCT TCTCACCATCACCCAACCACTTCAGCCTCACACTCCCATGGTGGAGGAGACAGCAGCATG ATGATGATGCCTATGACCTTCTACTTTGGCTTTAAGAATGTGGAACTACTGTTTTCCGGT TTGGTGATCAATACAGCTGGAGAAATGGCTGGAGCTTTTGTGGCAGTGTTTTTACTAGCA ATGTTCTATGAAGGACTCAAGATAGCCCGAGAGAGCCTGCTGCGTAAGTCACAAGTCAGC ATTCGCTACAATTCCATGCCTGTCCCAGGACCAAATGGAACCATCCTTATGGAGACACAC AAAACTGTTGGGCAACAGATGCTGAGCTTTCCTCACCTCCTGCAAACAGTGCTGCACATC ATCCAGGTGGTCATAAGCTACTTCCTCATGCTCATCTTCATGACCTACAACGGGTACCTC TGCATTGCAGTAGCAGCAGGGGCCGGTACAGGATACTTCCTCTTCAGCTGGAAGAAGGCA GTGGTAGTGGATATCACAGAGCATTGCCATTGA
- Chromosome Location
- 9
- Locus
- 9q31-q32
- External Identifiers
Resource Link UniProtKB ID O15431 UniProtKB Entry Name COPT1_HUMAN GenBank Protein ID 2315987 GenBank Gene ID U83460 HGNC ID HGNC:11016 - General References
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