Displaying drugs 1 - 25 of 68 in total
Thrombin
Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot.
Medical thrombin is a protein substance produced...
Approved
Investigational
Matched Synonyms: … Thrombin bovine ... Thrombin, Topical (Bovine) …
Matched Description: … Patients who are know or suspected to have antibodies to bovine thrombin and/or bovine factor V should ... Bleeding may result from the development of antibodies against bovine factor V [FDA Label]. ... Bovine thrombin however, is capable of causing fatal severe bleeding or thrombosis [FDA Label]. …
Matched Description: … Patients who are know or suspected to have antibodies to bovine thrombin and/or bovine factor V should ... Bleeding may result from the development of antibodies against bovine factor V [FDA Label]. ... Bovine thrombin however, is capable of causing fatal severe bleeding or thrombosis [FDA Label]. …
Desoxyribonuclease
Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release of free phosphoric acid. The enzyme's cofactor is reported to be...
Approved
Matched Synonyms: … Deoxyribonuclease, bovine ... Deoxyribonuclease I bovine ... Bovine pancreatic deoxyribonuclease …
Insulin beef
Insulin beef has been discontinued in the US and Canada since 2017.
Approved
Matched Synonyms: … Insulin bovine …
Pepsin
Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products .
Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated...
Approved
Experimental
Investigational
Matched Synonyms: … Pepsin, bovine …
Casein
Casein allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Bovine casein …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, ... (CYS74>SER,ALA245>THR)ADENOSINE DEAMINASE (BOS TAURUS, BOVINE)-(1-356)-PEPTIDE, PRODUCED IN ESCHERICHIA …
Matched Description: … It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification …
Matched Description: … It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification …
Rotavirus vaccine
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. …
rhThrombin
rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to achieving hemostasis during surgery. ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery. Thrombin is used in...
Approved
Investigational
Matched Description: … Currently, only thrombin derived from bovine blood is available in the U.S. as a stand-alone thrombin ... Bovine-derived thrombin has been associated with the development of antibodies that may cross-react with …
Danaparoid
Danaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans . The active constituents are heparan, dermatan and DB09301 , and they are isolated from the porcine intestinal mucosa [FDA Label]. Danaparoid possesses a potent antithrombic activity that works by inhibiting...
Approved
Withdrawn
Matched Description: … low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans …
Matched Categories: … Glycosaminoglycans …
Matched Categories: … Glycosaminoglycans …
Heparin
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Categories: … Glycosaminoglycans …
Matched Products: … HEPARINOL 10000 IU/mL (Heparin Sodium (Bovine) Injection BP 10000 IU/mL) …
Matched Products: … HEPARINOL 10000 IU/mL (Heparin Sodium (Bovine) Injection BP 10000 IU/mL) …
Fenoprofen
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Hyaluronic acid
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Description: … Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “ …
Matched Categories: … Glycosaminoglycans …
Matched Categories: … Glycosaminoglycans …
Chymopapain
Chymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by squeezing the green papaya while on the plant prior to harvest. It is an extracellular plant cysteine proteinase similar to papain in specificity. Chymopapain was developed by Chart Medcl and FDA approved...
Approved
Withdrawn
Certoparin
Certoparin is part of the heparins of low molecular weight that presents high activity against the coagulation factor Xa. It is normally used to prevent deep venous thrombosis.
Approved
Investigational
Matched Categories: … Glycosaminoglycans …
Rose bengal
Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression...
Approved
Investigational
Reviparin
Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...
Approved
Investigational
Matched Categories: … Glycosaminoglycans …
Tinzaparin
Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Categories: … Glycosaminoglycans …
Antithrombin III human
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Categories: … Glycosaminoglycans …
Trypsin
Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. When converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of the amino acids lysine or arginine....
Approved
Vet approved
Matched Description: … Therapeutic forms of trypsin is obtained from purified extracts of porcine or bovine pancreas and is …
Beractant
Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as SP-B and SP-C. The...
Approved
Matched Description: … Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains …
Bovine type I collagen
Bovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons and other connective tissues. It plays a vital role in cell growth, differentiation, attachment, and migration . Often combined with other ingredients, such as fibroblasts and keratinocytes, it allows for accelerated and effective wound healing...
Approved
Matched Synonyms: … Collagen Type I, Bovine …
Matched Name: … Bovine type I collagen …
Matched Description: … Bovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons ... Bovine type I collagen is also used as a health supplement for bones and joints [A32698]. ... Interestingly, bovine type I collagen has been studied as a possible endovascular stent material, and …
Matched Name: … Bovine type I collagen …
Matched Description: … Bovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons ... Bovine type I collagen is also used as a health supplement for bones and joints [A32698]. ... Interestingly, bovine type I collagen has been studied as a possible endovascular stent material, and …
Pegademase
Bovine adenosine deaminase derived from bovine intestine that has been extensively pegylated for extended serum half life.
Approved
Matched Synonyms: … Pegademase bovine …
Matched Description: … Bovine adenosine deaminase derived from bovine intestine that has been extensively pegylated for extended …
Matched Categories: … Bovine Intestinal Adenosine Deaminase …
Matched Description: … Bovine adenosine deaminase derived from bovine intestine that has been extensively pegylated for extended …
Matched Categories: … Bovine Intestinal Adenosine Deaminase …
Beef liver
Beef liver allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Bovine liver …
Bos taurus dander
Bos taurus dander allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Bovine dander …
Displaying drugs 1 - 25 of 68 in total