Rotavirus Vaccine

Identification

Name
Rotavirus Vaccine
Accession Number
DB10276  (DB10303, DB10304, DB10305, DB10306, DB10307)
Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Other vaccines
Description

Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration [2]. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains [1]. Rotarix is a live attenuated vaccine containing the 89-12 human strain [FDA Label]. Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection [2].

Synonyms
  • Rota virus, live attenuated
  • Rotavirus vaccine, live, oral
Product Ingredients
IngredientUNIICASInChI Key
Human Rotavirus A type G1P(8) strain RIX4414 live antigenKZ3L01D2PCNot AvailableNot applicable
Human Rotavirus A type G1P7(5) strain WI79 live antigen25VC15141QNot AvailableNot applicable
Human Rotavirus A type G2P7(5) strain SC2 live antigenJU499IS53HNot AvailableNot applicable
Human Rotavirus A type G3P7(5) strain WI78 live antigen236YGP181ONot AvailableNot applicable
Human Rotavirus A type G4P7(5) strain BRB live antigen6334XMP4KCNot AvailableNot applicable
Human Rotavirus A type G6P1A(8) strain WI79 live antigenL1977Q86S5Not AvailableNot applicable
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
RotarixKitGlaxo Smith Kline Biologicals Sa2011-01-13Not applicableUs
RotarixSuspension1000000 ccid50OralGlaxosmithkline Inc2008-12-16Not applicableCanada
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2800000 [iU]/2mL) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2000000 [iU]/2mL) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2300000 [iU]/2mL)SolutionOralMerck Sharp & Dohme Limited2006-02-03Not applicableUs
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2210000 unit) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2840000 unit) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2220000 unit) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2040000 unit) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2290000 unit)SolutionOralMerck Ltd.2006-10-16Not applicableCanada
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2800000 [iU]/2mL) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2000000 [iU]/2mL) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2300000 [iU]/2mL)SolutionOralMerck Sharp & Dohme Limited2006-02-03Not applicableUs
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2210000 unit) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2840000 unit) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2220000 unit) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2040000 unit) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2290000 unit)SolutionOralMerck Ltd.2006-10-16Not applicableCanada
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2800000 [iU]/2mL) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2000000 [iU]/2mL) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2300000 [iU]/2mL)SolutionOralMerck Sharp & Dohme Limited2006-02-03Not applicableUs
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2210000 unit) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2840000 unit) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2220000 unit) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2040000 unit) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2290000 unit)SolutionOralMerck Ltd.2006-10-16Not applicableCanada
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2800000 [iU]/2mL) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2000000 [iU]/2mL) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2300000 [iU]/2mL)SolutionOralMerck Sharp & Dohme Limited2006-02-03Not applicableUs
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2210000 unit) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2840000 unit) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2220000 unit) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2040000 unit) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2290000 unit)SolutionOralMerck Ltd.2006-10-16Not applicableCanada
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2800000 [iU]/2mL) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2200000 [iU]/2mL) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2000000 [iU]/2mL) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2300000 [iU]/2mL)SolutionOralMerck Sharp & Dohme Limited2006-02-03Not applicableUs
RotaTeqHuman Rotavirus A type G1P7(5) strain WI79 live antigen (2210000 unit) + Human Rotavirus A type G2P7(5) strain SC2 live antigen (2840000 unit) + Human Rotavirus A type G3P7(5) strain WI78 live antigen (2220000 unit) + Human Rotavirus A type G4P7(5) strain BRB live antigen (2040000 unit) + Human Rotavirus A type G6P1A(8) strain WI79 live antigen (2290000 unit)SolutionOralMerck Ltd.2006-10-16Not applicableCanada
Categories
UNII
Not Available
CAS number
Not Available

Pharmacology

Indication

Rotarix is indicated for prevention of rotavirus gastroenteritis caused by G1, G3, G4, and G9 types in infants aged 6-24 weeks [FDA Label].

Rotateq is indicated for the prevention of rotavirus gastroenteritis caused by G1, G2, G3, G4, and G9 types in infants aged 6-32 weeks [1].

Associated Conditions
Pharmacodynamics

Rotarix and Rotateq contain live attenuated and live virus respectively. The virus replicates in the intesine and interacts with the patient's immune system to produce immunity [FDA Label]. Seroconversion has been defined as the appearance of anti-rotavirus IgA antibodies at concentrations greater than 20 U/mL post-vaccination in the serum of infants previously negative for rotavirus [FDA Label].

Mechanism of action

The exact mechanism specific to the rotavirus vaccines' interaction with the immune system is uncharacterized [FDA Label].

Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life

The median duration of viral shedding was observed to be 10 days [FDA Label].

Clearance
Not Available
Toxicity

Rotavirus vaccine may produce severe diarrhea and vomiting as a result of rotavirus infection [FDA Label]. Post marketing reports suggest an increased risk of intussusception with rotavirus vaccine but this is unsupported by clinical data.

Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
16-BromoepiandrosteroneThe risk or severity of adverse effects can be increased when 16-Bromoepiandrosterone is combined with Rotavirus Vaccine.Investigational
19-norandrostenedioneThe risk or severity of adverse effects can be increased when 19-norandrostenedione is combined with Rotavirus Vaccine.Experimental, Illicit
2-MethoxyethanolThe risk or severity of adverse effects can be increased when 2-Methoxyethanol is combined with Rotavirus Vaccine.Experimental
5-androstenedioneThe risk or severity of adverse effects can be increased when 5-androstenedione is combined with Rotavirus Vaccine.Experimental, Illicit
AbataceptThe risk or severity of adverse effects can be increased when Abatacept is combined with Rotavirus Vaccine.Approved
AbciximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Abciximab.Approved
AbetimusThe risk or severity of adverse effects can be increased when Abetimus is combined with Rotavirus Vaccine.Investigational
AbituzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Abituzumab.Investigational
ActeosideThe risk or severity of adverse effects can be increased when Acteoside is combined with Rotavirus Vaccine.Investigational
AdalimumabThe risk or severity of adverse effects can be increased when Adalimumab is combined with Rotavirus Vaccine.Approved
AdecatumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Adecatumumab.Investigational
AdefovirThe risk or severity of adverse effects can be increased when Adefovir is combined with Rotavirus Vaccine.Investigational
AducanumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Aducanumab.Investigational
AfelimomabThe risk or severity of adverse effects can be increased when Afelimomab is combined with Rotavirus Vaccine.Investigational
AlclometasoneThe risk or severity of adverse effects can be increased when Alclometasone is combined with Rotavirus Vaccine.Approved
AldosteroneThe risk or severity of adverse effects can be increased when Aldosterone is combined with Rotavirus Vaccine.Experimental, Investigational
AlefaceptThe risk or severity of adverse effects can be increased when Alefacept is combined with Rotavirus Vaccine.Approved, Investigational, Withdrawn
AlemtuzumabThe risk or severity of adverse effects can be increased when Alemtuzumab is combined with Rotavirus Vaccine.Approved, Investigational
AlicaforsenThe risk or severity of adverse effects can be increased when Alicaforsen is combined with Rotavirus Vaccine.Investigational
AlirocumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Alirocumab.Approved
AltretamineThe risk or severity of adverse effects can be increased when Altretamine is combined with Rotavirus Vaccine.Approved
AmatuximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Amatuximab.Investigational
AmcinonideThe risk or severity of adverse effects can be increased when Amcinonide is combined with Rotavirus Vaccine.Approved
AMG 108The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with AMG 108.Investigational
AmsacrineThe risk or severity of adverse effects can be increased when Amsacrine is combined with Rotavirus Vaccine.Approved, Investigational
AnakinraThe risk or severity of adverse effects can be increased when Anakinra is combined with Rotavirus Vaccine.Approved
AndrostenedioneThe risk or severity of adverse effects can be increased when Androstenedione is combined with Rotavirus Vaccine.Experimental, Illicit
AnecortaveThe risk or severity of adverse effects can be increased when Anecortave is combined with Rotavirus Vaccine.Investigational
anecortave acetateThe risk or severity of adverse effects can be increased when anecortave acetate is combined with Rotavirus Vaccine.Investigational
AnifrolumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Anifrolumab.Investigational
Antilymphocyte immunoglobulin (horse)The risk or severity of adverse effects can be increased when Antilymphocyte immunoglobulin (horse) is combined with Rotavirus Vaccine.Approved, Investigational
Antithymocyte immunoglobulin (rabbit)The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Rotavirus Vaccine.Approved
ApolizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Apolizumab.Investigational
ApremilastThe risk or severity of adverse effects can be increased when Apremilast is combined with Rotavirus Vaccine.Approved, Investigational
AscrinvacumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ascrinvacumab.Investigational
Asfotase AlfaThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Asfotase Alfa.Approved, Investigational
AtamestaneThe risk or severity of adverse effects can be increased when Atamestane is combined with Rotavirus Vaccine.Investigational
AtezolizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Atezolizumab.Approved, Investigational
AVE9633The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with AVE9633.Investigational
AvelumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Avelumab.Approved, Investigational
AzacitidineThe risk or severity of adverse effects can be increased when Azacitidine is combined with Rotavirus Vaccine.Approved, Investigational
AzathioprineThe risk or severity of adverse effects can be increased when Azathioprine is combined with Rotavirus Vaccine.Approved
BapineuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Bapineuzumab.Investigational
BasiliximabThe risk or severity of adverse effects can be increased when Basiliximab is combined with Rotavirus Vaccine.Approved, Investigational
BavituximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Bavituximab.Investigational
Beclomethasone dipropionateThe risk or severity of adverse effects can be increased when Beclomethasone dipropionate is combined with Rotavirus Vaccine.Approved, Investigational
BectumomabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Bectumomab.Investigational
BegelomabThe risk or severity of adverse effects can be increased when Begelomab is combined with Rotavirus Vaccine.Experimental, Investigational
BelataceptThe risk or severity of adverse effects can be increased when Belatacept is combined with Rotavirus Vaccine.Approved, Investigational
BelimumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Belimumab.Approved
BenznidazoleThe risk or severity of adverse effects can be increased when Benznidazole is combined with Rotavirus Vaccine.Approved, Investigational
BesilesomabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Besilesomab.Approved
BetamethasoneThe risk or severity of adverse effects can be increased when Betamethasone is combined with Rotavirus Vaccine.Approved, Vet Approved
BevacizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Bevacizumab.Approved, Investigational
BIIB015The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with BIIB015.Investigational
BimagrumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Bimagrumab.Investigational
BivatuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Bivatuzumab.Investigational
BleomycinThe risk or severity of adverse effects can be increased when Bleomycin is combined with Rotavirus Vaccine.Approved, Investigational
BlinatumomabThe risk or severity of adverse effects can be increased when Blinatumomab is combined with Rotavirus Vaccine.Approved, Investigational
BlosozumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Blosozumab.Investigational
BococizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Bococizumab.Investigational
Brentuximab vedotinThe risk or severity of adverse effects can be increased when Brentuximab vedotin is combined with Rotavirus Vaccine.Approved, Investigational
BriakinumabThe risk or severity of adverse effects can be increased when Briakinumab is combined with Rotavirus Vaccine.Investigational
BrodalumabThe risk or severity of adverse effects can be increased when Brodalumab is combined with Rotavirus Vaccine.Approved, Investigational
BudesonideThe risk or severity of adverse effects can be increased when Budesonide is combined with Rotavirus Vaccine.Approved
BusulfanThe risk or severity of adverse effects can be increased when Busulfan is combined with Rotavirus Vaccine.Approved, Investigational
CabazitaxelThe risk or severity of adverse effects can be increased when Cabazitaxel is combined with Rotavirus Vaccine.Approved
CanakinumabThe risk or severity of adverse effects can be increased when Canakinumab is combined with Rotavirus Vaccine.Approved, Investigational
CapecitabineThe risk or severity of adverse effects can be increased when Capecitabine is combined with Rotavirus Vaccine.Approved, Investigational
CaplacizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Caplacizumab.Investigational
Capromab pendetideThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Capromab pendetide.Approved
CarboplatinThe risk or severity of adverse effects can be increased when Carboplatin is combined with Rotavirus Vaccine.Approved
CarlumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Carlumab.Investigational
CarmustineThe risk or severity of adverse effects can be increased when Carmustine is combined with Rotavirus Vaccine.Approved, Investigational
CastanospermineThe risk or severity of adverse effects can be increased when Castanospermine is combined with Rotavirus Vaccine.Experimental
CatumaxomabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Catumaxomab.Approved, Investigational, Withdrawn
Certolizumab pegolThe risk or severity of adverse effects can be increased when Certolizumab pegol is combined with Rotavirus Vaccine.Approved
CetuximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Cetuximab.Approved
ChlorambucilThe risk or severity of adverse effects can be increased when Chlorambucil is combined with Rotavirus Vaccine.Approved
CiclesonideThe risk or severity of adverse effects can be increased when Ciclesonide is combined with Rotavirus Vaccine.Approved, Investigational
CisplatinThe risk or severity of adverse effects can be increased when Cisplatin is combined with Rotavirus Vaccine.Approved
CixutumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Cixutumumab.Investigational
CladribineThe risk or severity of adverse effects can be increased when Cladribine is combined with Rotavirus Vaccine.Approved, Investigational
ClazakizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Clazakizumab.Investigational
ClenoliximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Clenoliximab.Investigational
ClobetasolThe risk or severity of adverse effects can be increased when Clobetasol is combined with Rotavirus Vaccine.Approved, Investigational
Clobetasol propionateThe risk or severity of adverse effects can be increased when Clobetasol propionate is combined with Rotavirus Vaccine.Approved
ClobetasoneThe risk or severity of adverse effects can be increased when Clobetasone is combined with Rotavirus Vaccine.Approved
ClocortoloneThe risk or severity of adverse effects can be increased when Clocortolone is combined with Rotavirus Vaccine.Approved
ClofarabineThe risk or severity of adverse effects can be increased when Clofarabine is combined with Rotavirus Vaccine.Approved, Investigational
Coltuximab ravtansineThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Coltuximab ravtansine.Investigational
ConatumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Conatumumab.Investigational
ConcizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Concizumab.Investigational
Cortexolone 17α-propionateThe risk or severity of adverse effects can be increased when Cortexolone 17α-propionate is combined with Rotavirus Vaccine.Investigational
CorticosteroneThe risk or severity of adverse effects can be increased when Corticosterone is combined with Rotavirus Vaccine.Experimental
CorticotropinThe risk or severity of adverse effects can be increased when Corticotropin is combined with Rotavirus Vaccine.Approved, Investigational, Vet Approved
Cortisone acetateThe risk or severity of adverse effects can be increased when Cortisone acetate is combined with Rotavirus Vaccine.Approved, Investigational
CR002The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with CR002.Investigational
CrenezumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Crenezumab.Investigational
CrotedumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Crotedumab.Investigational
CyclophosphamideThe risk or severity of adverse effects can be increased when Cyclophosphamide is combined with Rotavirus Vaccine.Approved, Investigational
CyclosporineThe risk or severity of adverse effects can be increased when Cyclosporine is combined with Rotavirus Vaccine.Approved, Investigational, Vet Approved
CytarabineThe risk or severity of adverse effects can be increased when Cytarabine is combined with Rotavirus Vaccine.Approved, Investigational
DacarbazineThe risk or severity of adverse effects can be increased when Dacarbazine is combined with Rotavirus Vaccine.Approved, Investigational
DacetuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Dacetuzumab.Investigational
DaclizumabThe risk or severity of adverse effects can be increased when Daclizumab is combined with Rotavirus Vaccine.Investigational, Withdrawn
DactinomycinThe risk or severity of adverse effects can be increased when Dactinomycin is combined with Rotavirus Vaccine.Approved, Investigational
DalotuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Dalotuzumab.Investigational
DaratumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Daratumumab.Approved
DasatinibThe risk or severity of adverse effects can be increased when Dasatinib is combined with Rotavirus Vaccine.Approved, Investigational
DaunorubicinThe risk or severity of adverse effects can be increased when Daunorubicin is combined with Rotavirus Vaccine.Approved
DeflazacortThe risk or severity of adverse effects can be increased when Deflazacort is combined with Rotavirus Vaccine.Approved, Investigational
DemcizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Demcizumab.Investigational
DenosumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Denosumab.Approved
DeoxyspergualinThe risk or severity of adverse effects can be increased when Deoxyspergualin is combined with Rotavirus Vaccine.Investigational
DepatuxizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Depatuxizumab.Investigational
DesonideThe risk or severity of adverse effects can be increased when Desonide is combined with Rotavirus Vaccine.Approved, Investigational
DesoximetasoneThe risk or severity of adverse effects can be increased when Desoximetasone is combined with Rotavirus Vaccine.Approved
Desoxycorticosterone acetateThe risk or severity of adverse effects can be increased when Desoxycorticosterone acetate is combined with Rotavirus Vaccine.Approved
Desoxycorticosterone PivalateThe risk or severity of adverse effects can be increased when Desoxycorticosterone Pivalate is combined with Rotavirus Vaccine.Experimental, Vet Approved
DexamethasoneThe risk or severity of adverse effects can be increased when Dexamethasone is combined with Rotavirus Vaccine.Approved, Investigational, Vet Approved
Dexamethasone isonicotinateThe risk or severity of adverse effects can be increased when Dexamethasone isonicotinate is combined with Rotavirus Vaccine.Vet Approved
DiflorasoneThe risk or severity of adverse effects can be increased when Diflorasone is combined with Rotavirus Vaccine.Approved
DifluocortoloneThe risk or severity of adverse effects can be increased when Difluocortolone is combined with Rotavirus Vaccine.Approved, Investigational, Withdrawn
DifluprednateThe risk or severity of adverse effects can be increased when Difluprednate is combined with Rotavirus Vaccine.Approved
Dimethyl fumarateThe risk or severity of adverse effects can be increased when Dimethyl fumarate is combined with Rotavirus Vaccine.Approved, Investigational
DinutuximabThe risk or severity of adverse effects can be increased when Dinutuximab is combined with Rotavirus Vaccine.Approved, Investigational
DocetaxelThe risk or severity of adverse effects can be increased when Docetaxel is combined with Rotavirus Vaccine.Approved, Investigational
DoxifluridineThe risk or severity of adverse effects can be increased when Doxifluridine is combined with Rotavirus Vaccine.Investigational
DoxorubicinThe risk or severity of adverse effects can be increased when Doxorubicin is combined with Rotavirus Vaccine.Approved, Investigational
DulaglutideThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Dulaglutide.Approved, Investigational
DuligotuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Duligotuzumab.Investigational
DupilumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Dupilumab.Approved, Investigational
DurvalumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Durvalumab.Approved, Investigational
DusigitumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Dusigitumab.Investigational
EculizumabThe risk or severity of adverse effects can be increased when Eculizumab is combined with Rotavirus Vaccine.Approved, Investigational
EdrecolomabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Edrecolomab.Experimental, Investigational
EfalizumabThe risk or severity of adverse effects can be increased when Efalizumab is combined with Rotavirus Vaccine.Approved, Investigational
EldelumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Eldelumab.Investigational
ElotuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Elotuzumab.Approved
EmibetuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Emibetuzumab.Investigational
EmicizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Emicizumab.Approved, Investigational
EnokizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Enokizumab.Investigational
EpirubicinThe risk or severity of adverse effects can be increased when Epirubicin is combined with Rotavirus Vaccine.Approved
EpratuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Epratuzumab.Investigational
EquileninThe risk or severity of adverse effects can be increased when Equilenin is combined with Rotavirus Vaccine.Experimental
EquilinThe risk or severity of adverse effects can be increased when Equilin is combined with Rotavirus Vaccine.Approved
ErenumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Erenumab.Approved, Investigational
EstramustineThe risk or severity of adverse effects can be increased when Estramustine is combined with Rotavirus Vaccine.Approved, Investigational
EstroneThe risk or severity of adverse effects can be increased when Estrone is combined with Rotavirus Vaccine.Approved
Estrone sulfateThe risk or severity of adverse effects can be increased when Estrone sulfate is combined with Rotavirus Vaccine.Approved
EtanerceptThe risk or severity of adverse effects can be increased when Etanercept is combined with Rotavirus Vaccine.Approved, Investigational
EtaracizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Etaracizumab.Investigational
EtoposideThe risk or severity of adverse effects can be increased when Etoposide is combined with Rotavirus Vaccine.Approved
EtrolizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Etrolizumab.Investigational
EverolimusThe risk or severity of adverse effects can be increased when Everolimus is combined with Rotavirus Vaccine.Approved
EvolocumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Evolocumab.Approved
FarletuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Farletuzumab.Investigational
FiclatuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ficlatuzumab.Investigational
FigitumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Figitumumab.Investigational
FingolimodThe risk or severity of adverse effects can be increased when Fingolimod is combined with Rotavirus Vaccine.Approved, Investigational
FirategrastThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Firategrast.Investigational
FloxuridineThe risk or severity of adverse effects can be increased when Floxuridine is combined with Rotavirus Vaccine.Approved
FluasteroneThe risk or severity of adverse effects can be increased when Fluasterone is combined with Rotavirus Vaccine.Investigational
FludarabineThe risk or severity of adverse effects can be increased when Fludarabine is combined with Rotavirus Vaccine.Approved
FludrocortisoneThe risk or severity of adverse effects can be increased when Fludrocortisone is combined with Rotavirus Vaccine.Approved, Investigational
FlumethasoneThe risk or severity of adverse effects can be increased when Flumethasone is combined with Rotavirus Vaccine.Approved, Vet Approved
FlunisolideThe risk or severity of adverse effects can be increased when Flunisolide is combined with Rotavirus Vaccine.Approved, Investigational
Fluocinolone AcetonideThe risk or severity of adverse effects can be increased when Fluocinolone Acetonide is combined with Rotavirus Vaccine.Approved, Investigational, Vet Approved
FluocinonideThe risk or severity of adverse effects can be increased when Fluocinonide is combined with Rotavirus Vaccine.Approved, Investigational
FluocortoloneThe risk or severity of adverse effects can be increased when Fluocortolone is combined with Rotavirus Vaccine.Approved, Withdrawn
FluorometholoneThe risk or severity of adverse effects can be increased when Fluorometholone is combined with Rotavirus Vaccine.Approved, Investigational
FluorouracilThe risk or severity of adverse effects can be increased when Fluorouracil is combined with Rotavirus Vaccine.Approved
FluprednideneThe risk or severity of adverse effects can be increased when Fluprednidene is combined with Rotavirus Vaccine.Approved, Withdrawn
FluprednisoloneThe risk or severity of adverse effects can be increased when Fluprednisolone is combined with Rotavirus Vaccine.Approved
FlurandrenolideThe risk or severity of adverse effects can be increased when Flurandrenolide is combined with Rotavirus Vaccine.Approved
FluticasoneThe risk or severity of adverse effects can be increased when Fluticasone is combined with Rotavirus Vaccine.Approved, Experimental, Investigational
Fluticasone furoateThe risk or severity of adverse effects can be increased when Fluticasone furoate is combined with Rotavirus Vaccine.Approved
Fluticasone propionateThe risk or severity of adverse effects can be increased when Fluticasone propionate is combined with Rotavirus Vaccine.Approved
FontolizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Fontolizumab.Investigational
FormestaneThe risk or severity of adverse effects can be increased when Formestane is combined with Rotavirus Vaccine.Approved, Investigational, Withdrawn
FremanezumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Fremanezumab.Investigational
FresolimumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Fresolimumab.Investigational
FulranumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Fulranumab.Investigational
GaliximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Galiximab.Investigational
Gallium nitrateThe risk or severity of adverse effects can be increased when Gallium nitrate is combined with Rotavirus Vaccine.Approved, Investigational
GanitumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ganitumab.Investigational
GantenerumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Gantenerumab.Investigational
GemcitabineThe risk or severity of adverse effects can be increased when Gemcitabine is combined with Rotavirus Vaccine.Approved
Gemtuzumab ozogamicinThe risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Rotavirus Vaccine.Approved, Investigational
GevokizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Gevokizumab.Investigational
GlatiramerThe risk or severity of adverse effects can be increased when Glatiramer Acetate is combined with Rotavirus Vaccine.Approved, Investigational
Glembatumumab vedotinThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Glembatumumab vedotin.Investigational
GlimepirideThe risk or severity of adverse effects can be increased when Glimepiride is combined with Rotavirus Vaccine.Approved
GolimumabThe risk or severity of adverse effects can be increased when Golimumab is combined with Rotavirus Vaccine.Approved
GS 0573The risk or severity of adverse effects can be increased when GS 0573 is combined with Rotavirus Vaccine.Investigational
GuselkumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Guselkumab.Approved, Investigational
GusperimusThe risk or severity of adverse effects can be increased when Gusperimus is combined with Rotavirus Vaccine.Investigational
HalcinonideThe risk or severity of adverse effects can be increased when Halcinonide is combined with Rotavirus Vaccine.Approved, Investigational, Withdrawn
HE3286The risk or severity of adverse effects can be increased when HE3286 is combined with Rotavirus Vaccine.Investigational
Human C1-esterase inhibitorThe risk or severity of adverse effects can be increased when Human C1-esterase inhibitor is combined with Rotavirus Vaccine.Approved
Human cytomegalovirus immune globulinThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Human cytomegalovirus immune globulin.Approved
Human Varicella-Zoster Immune GlobulinThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Human Varicella-Zoster Immune Globulin.Approved
HydrocortisoneThe risk or severity of adverse effects can be increased when Hydrocortisone is combined with Rotavirus Vaccine.Approved, Vet Approved
HydroxyureaThe risk or severity of adverse effects can be increased when Hydroxyurea is combined with Rotavirus Vaccine.Approved
HypericinThe risk or severity of adverse effects can be increased when Hypericin is combined with Rotavirus Vaccine.Investigational
IbalizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ibalizumab.Approved, Investigational
Ibritumomab tiuxetanThe risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Rotavirus Vaccine.Approved, Investigational
IbrutinibThe risk or severity of adverse effects can be increased when Ibrutinib is combined with Rotavirus Vaccine.Approved
IcatibantThe risk or severity of adverse effects can be increased when Icatibant is combined with Rotavirus Vaccine.Approved, Investigational
IdarubicinThe risk or severity of adverse effects can be increased when Idarubicin is combined with Rotavirus Vaccine.Approved
IdarucizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Idarucizumab.Approved
IdelalisibThe risk or severity of adverse effects can be increased when Idelalisib is combined with Rotavirus Vaccine.Approved
IfosfamideThe risk or severity of adverse effects can be increased when Ifosfamide is combined with Rotavirus Vaccine.Approved
IGN311The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with IGN311.Investigational
ImatinibThe risk or severity of adverse effects can be increased when Imatinib is combined with Rotavirus Vaccine.Approved
IMC-1C11The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with IMC-1C11.Investigational
ImiquimodThe risk or severity of adverse effects can be increased when Imiquimod is combined with Rotavirus Vaccine.Approved, Investigational
Immune Globulin HumanThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Immune Globulin Human.Approved, Investigational
InclacumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Inclacumab.Investigational
Indium In-111 satumomab pendetideThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Indium In-111 satumomab pendetide.Approved, Withdrawn
InebilizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Inebilizumab.Investigational
InfliximabThe risk or severity of adverse effects can be increased when Infliximab is combined with Rotavirus Vaccine.Approved
Inotuzumab ozogamicinThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Inotuzumab ozogamicin.Approved, Investigational
IntetumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Intetumumab.Investigational
IPH 2101The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with IPH 2101.Investigational
IpilimumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ipilimumab.Approved
IratumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Iratumumab.Investigational
IrinotecanThe risk or severity of adverse effects can be increased when Irinotecan is combined with Rotavirus Vaccine.Approved, Investigational
IstaroximeThe risk or severity of adverse effects can be increased when Istaroxime is combined with Rotavirus Vaccine.Investigational
IxekizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ixekizumab.Approved, Investigational
L-PhenylalanineThe risk or severity of adverse effects can be increased when L-Phenylalanine is combined with Rotavirus Vaccine.Approved, Investigational, Nutraceutical
LabetuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Labetuzumab.Investigational
LampalizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Lampalizumab.Investigational
LandogrozumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Landogrozumab.Investigational
LeflunomideThe risk or severity of adverse effects can be increased when Leflunomide is combined with Rotavirus Vaccine.Approved, Investigational
LenalidomideThe risk or severity of adverse effects can be increased when Lenalidomide is combined with Rotavirus Vaccine.Approved
LerdelimumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Lerdelimumab.Investigational
LexatumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Lexatumumab.Investigational
LigelizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ligelizumab.Investigational
LisofyllineThe risk or severity of adverse effects can be increased when Lisofylline is combined with Rotavirus Vaccine.Investigational
LomustineThe risk or severity of adverse effects can be increased when Lomustine is combined with Rotavirus Vaccine.Approved, Investigational
Lorvotuzumab mertansineThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Lorvotuzumab mertansine.Investigational
LoteprednolThe risk or severity of adverse effects can be increased when Loteprednol is combined with Rotavirus Vaccine.Approved
LucatumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Lucatumumab.Investigational
LumiliximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Lumiliximab.Investigational
MatuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Matuzumab.Investigational
MavrilimumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Mavrilimumab.Investigational
ME-609The risk or severity of adverse effects can be increased when ME-609 is combined with Rotavirus Vaccine.Investigational
MechlorethamineThe risk or severity of adverse effects can be increased when Mechlorethamine is combined with Rotavirus Vaccine.Approved, Investigational
MedrysoneThe risk or severity of adverse effects can be increased when Medrysone is combined with Rotavirus Vaccine.Approved
MelengestrolThe risk or severity of adverse effects can be increased when Melengestrol is combined with Rotavirus Vaccine.Vet Approved
MelphalanThe risk or severity of adverse effects can be increased when Melphalan is combined with Rotavirus Vaccine.Approved
MepolizumabThe risk or severity of adverse effects can be increased when Mepolizumab is combined with Rotavirus Vaccine.Approved, Investigational
MercaptopurineThe risk or severity of adverse effects can be increased when Mercaptopurine is combined with Rotavirus Vaccine.Approved
MethotrexateThe risk or severity of adverse effects can be increased when Methotrexate is combined with Rotavirus Vaccine.Approved
MethylprednisoloneThe risk or severity of adverse effects can be increased when Methylprednisolone is combined with Rotavirus Vaccine.Approved, Vet Approved
MilatuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Milatuzumab.Investigational
Mirvetuximab SoravtansineThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Mirvetuximab Soravtansine.Investigational
MitomycinThe risk or severity of adverse effects can be increased when Mitomycin is combined with Rotavirus Vaccine.Approved
MitoxantroneThe risk or severity of adverse effects can be increased when Mitoxantrone is combined with Rotavirus Vaccine.Approved, Investigational
MizoribineThe risk or severity of adverse effects can be increased when Mizoribine is combined with Rotavirus Vaccine.Investigational
MogamulizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Mogamulizumab.Investigational
MometasoneThe risk or severity of adverse effects can be increased when Mometasone is combined with Rotavirus Vaccine.Approved, Vet Approved
MotavizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Motavizumab.Investigational
MuromonabThe risk or severity of adverse effects can be increased when Muromonab is combined with Rotavirus Vaccine.Approved, Investigational
Mycophenolate mofetilThe risk or severity of adverse effects can be increased when Mycophenolate mofetil is combined with Rotavirus Vaccine.Approved, Investigational
Mycophenolic acidThe risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Rotavirus Vaccine.Approved
MYO-029The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with MYO-029.Investigational
NafamostatThe risk or severity of adverse effects can be increased when Nafamostat is combined with Rotavirus Vaccine.Approved, Investigational
Naptumomab EstafenatoxThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Naptumomab Estafenatox.Investigational
NatalizumabThe risk or severity of adverse effects can be increased when Natalizumab is combined with Rotavirus Vaccine.Approved, Investigational
NCX 1022The risk or severity of adverse effects can be increased when NCX 1022 is combined with Rotavirus Vaccine.Investigational
NebacumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Nebacumab.Experimental
NecitumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Necitumumab.Approved, Investigational
NelarabineThe risk or severity of adverse effects can be increased when Nelarabine is combined with Rotavirus Vaccine.Approved, Investigational
NilotinibThe risk or severity of adverse effects can be increased when Nilotinib is combined with Rotavirus Vaccine.Approved, Investigational
NimotuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Nimotuzumab.Investigational
NivolumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Nivolumab.Approved
ObiltoxaximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Obiltoxaximab.Approved
ObinutuzumabThe risk or severity of adverse effects can be increased when Obinutuzumab is combined with Rotavirus Vaccine.Approved, Investigational
OcrelizumabThe therapeutic efficacy of Ocrelizumab can be decreased when used in combination with Rotavirus Vaccine.Approved, Investigational
OfatumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ofatumumab.Approved
OlaratumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Olaratumab.Approved, Investigational
Oleoyl-estroneThe risk or severity of adverse effects can be increased when Oleoyl-estrone is combined with Rotavirus Vaccine.Investigational
OlokizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Olokizumab.Investigational
OmalizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Omalizumab.Approved, Investigational
OnartuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Onartuzumab.Investigational
OregovomabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Oregovomab.Investigational
OtelixizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Otelixizumab.Investigational
OxaliplatinThe risk or severity of adverse effects can be increased when Oxaliplatin is combined with Rotavirus Vaccine.Approved, Investigational
OzanezumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ozanezumab.Investigational
PaclitaxelThe risk or severity of adverse effects can be increased when Paclitaxel is combined with Rotavirus Vaccine.Approved, Vet Approved
PalbociclibThe risk or severity of adverse effects can be increased when Palbociclib is combined with Rotavirus Vaccine.Approved, Investigational
PalivizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Palivizumab.Approved, Investigational
PanitumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Panitumumab.Approved, Investigational
PanobinostatThe risk or severity of adverse effects can be increased when Panobinostat is combined with Rotavirus Vaccine.Approved, Investigational
PaquinimodThe risk or severity of adverse effects can be increased when Paquinimod is combined with Rotavirus Vaccine.Investigational
ParamethasoneThe risk or severity of adverse effects can be increased when Paramethasone is combined with Rotavirus Vaccine.Approved
PatritumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Patritumab.Investigational
PazopanibThe risk or severity of adverse effects can be increased when Pazopanib is combined with Rotavirus Vaccine.Approved
PegaspargaseThe risk or severity of adverse effects can be increased when Pegaspargase is combined with Rotavirus Vaccine.Approved, Investigational
PembrolizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Pembrolizumab.Approved
PemetrexedThe risk or severity of adverse effects can be increased when Pemetrexed is combined with Rotavirus Vaccine.Approved, Investigational
PentostatinThe risk or severity of adverse effects can be increased when Pentostatin is combined with Rotavirus Vaccine.Approved, Investigational
PertuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Pertuzumab.Approved
PexelizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Pexelizumab.Investigational
PimecrolimusThe risk or severity of adverse effects can be increased when Pimecrolimus is combined with Rotavirus Vaccine.Approved, Investigational
PirarubicinThe risk or severity of adverse effects can be increased when Pirarubicin is combined with Rotavirus Vaccine.Investigational
PirfenidoneThe risk or severity of adverse effects can be increased when Pirfenidone is combined with Rotavirus Vaccine.Approved, Investigational
Polatuzumab VedotinThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Polatuzumab Vedotin.Investigational
PomalidomideThe risk or severity of adverse effects can be increased when Pomalidomide is combined with Rotavirus Vaccine.Approved
PralatrexateThe risk or severity of adverse effects can be increased when Pralatrexate is combined with Rotavirus Vaccine.Approved, Investigational
PrasteroneThe risk or severity of adverse effects can be increased when Prasterone is combined with Rotavirus Vaccine.Approved, Investigational, Nutraceutical
Prasterone sulfateThe risk or severity of adverse effects can be increased when Prasterone sulfate is combined with Rotavirus Vaccine.Investigational
PrednicarbateThe risk or severity of adverse effects can be increased when Prednicarbate is combined with Rotavirus Vaccine.Approved, Investigational
PrednisoloneThe risk or severity of adverse effects can be increased when Prednisolone is combined with Rotavirus Vaccine.Approved, Vet Approved
PrednisoneThe risk or severity of adverse effects can be increased when Prednisone is combined with Rotavirus Vaccine.Approved, Vet Approved
PregnenoloneThe risk or severity of adverse effects can be increased when Pregnenolone is combined with Rotavirus Vaccine.Approved, Experimental, Investigational
PRO 140The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with PRO 140.Investigational
PRO-542The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with PRO-542.Investigational
ProcarbazineThe risk or severity of adverse effects can be increased when Procarbazine is combined with Rotavirus Vaccine.Approved, Investigational
R1507The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with R1507.Investigational
RacotumomabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Racotumomab.Investigational
RamucirumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ramucirumab.Approved, Investigational
RanibizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Ranibizumab.Approved
RaxibacumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Raxibacumab.Approved
ReslizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Reslizumab.Approved, Investigational
RI 624The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with RI 624.Investigational
RIGScan CR49The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with RIGScan CR49.Investigational
RilonaceptThe risk or severity of adverse effects can be increased when Rilonacept is combined with Rotavirus Vaccine.Approved, Investigational
RilotumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Rilotumumab.Investigational
RimexoloneThe risk or severity of adverse effects can be increased when Rimexolone is combined with Rotavirus Vaccine.Approved
RituximabThe risk or severity of adverse effects can be increased when Rituximab is combined with Rotavirus Vaccine.Approved
RobatumumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Robatumumab.Investigational
RomosozumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Romosozumab.Investigational
RontalizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Rontalizumab.Investigational
RuxolitinibThe risk or severity of adverse effects can be increased when Ruxolitinib is combined with Rotavirus Vaccine.Approved
Sacituzumab govitecanThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Sacituzumab govitecan.Investigational
SarilumabThe risk or severity of infection can be increased when Sarilumab is combined with Rotavirus Vaccine.Approved, Investigational
SecukinumabThe risk or severity of adverse effects can be increased when Secukinumab is combined with Rotavirus Vaccine.Approved
SemapimodThe risk or severity of adverse effects can be increased when Semapimod is combined with Rotavirus Vaccine.Investigational
SeocalcitolThe risk or severity of adverse effects can be increased when Seocalcitol is combined with Rotavirus Vaccine.Experimental, Investigational
SeribantumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Seribantumab.Investigational
SibrotuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Sibrotuzumab.Investigational
SiltuximabThe risk or severity of adverse effects can be increased when Siltuximab is combined with Rotavirus Vaccine.Approved, Investigational
SiplizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Siplizumab.Investigational
SirolimusThe risk or severity of adverse effects can be increased when Sirolimus is combined with Rotavirus Vaccine.Approved, Investigational
SirukumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Sirukumab.Investigational
SolanezumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Solanezumab.Investigational
SorafenibThe risk or severity of adverse effects can be increased when Sorafenib is combined with Rotavirus Vaccine.Approved, Investigational
SteproninThe risk or severity of adverse effects can be increased when Stepronin is combined with Rotavirus Vaccine.Approved
StreptozocinThe risk or severity of adverse effects can be increased when Streptozocin is combined with Rotavirus Vaccine.Approved, Investigational
SulesomabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Sulesomab.Approved
SunitinibThe risk or severity of adverse effects can be increased when Sunitinib is combined with Rotavirus Vaccine.Approved, Investigational
SYM001The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with SYM001.Investigational
TabalumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Tabalumab.Investigational
TacrolimusThe risk or severity of adverse effects can be increased when Tacrolimus is combined with Rotavirus Vaccine.Approved, Investigational
TanezumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Tanezumab.Investigational
TarextumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Tarextumab.Investigational
TB-402The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with TB-402.Investigational
Technetium Tc-99m arcitumomabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Technetium Tc-99m arcitumomab.Approved, Investigational
TemozolomideThe risk or severity of adverse effects can be increased when Temozolomide is combined with Rotavirus Vaccine.Approved, Investigational
TemsirolimusThe risk or severity of adverse effects can be increased when Temsirolimus is combined with Rotavirus Vaccine.Approved
TeniposideThe risk or severity of adverse effects can be increased when Teniposide is combined with Rotavirus Vaccine.Approved
TeplizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Teplizumab.Investigational
TepoxalinThe risk or severity of adverse effects can be increased when Tepoxalin is combined with Rotavirus Vaccine.Vet Approved
TeriflunomideThe risk or severity of adverse effects can be increased when Teriflunomide is combined with Rotavirus Vaccine.Approved
Tetanus Immune GlobulinThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Tetanus Immune Globulin.Approved
ThalidomideThe risk or severity of adverse effects can be increased when Thalidomide is combined with Rotavirus Vaccine.Approved, Investigational, Withdrawn
ThiotepaThe risk or severity of adverse effects can be increased when Thiotepa is combined with Rotavirus Vaccine.Approved, Investigational
TildrakizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Tildrakizumab.Approved, Investigational
TioguanineThe risk or severity of adverse effects can be increased when Tioguanine is combined with Rotavirus Vaccine.Approved
TixocortolThe risk or severity of adverse effects can be increased when Tixocortol is combined with Rotavirus Vaccine.Approved, Withdrawn
TNX-901The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with TNX-901.Investigational
TocilizumabThe risk or severity of adverse effects can be increased when Tocilizumab is combined with Rotavirus Vaccine.Approved
TofacitinibThe risk or severity of adverse effects can be increased when Tofacitinib is combined with Rotavirus Vaccine.Approved, Investigational
TopotecanThe risk or severity of adverse effects can be increased when Topotecan is combined with Rotavirus Vaccine.Approved, Investigational
TositumomabThe risk or severity of adverse effects can be increased when Tositumomab is combined with Rotavirus Vaccine.Approved, Investigational
TovetumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Tovetumab.Investigational
TrabectedinThe risk or severity of adverse effects can be increased when Trabectedin is combined with Rotavirus Vaccine.Approved, Investigational
TralokinumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Tralokinumab.Investigational
TrastuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Trastuzumab.Approved, Investigational
Trastuzumab emtansineThe risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Rotavirus Vaccine.Approved, Investigational
TRC105The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with TRC105.Investigational
TremelimumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Tremelimumab.Investigational
TretinoinThe risk or severity of adverse effects can be increased when Tretinoin is combined with Rotavirus Vaccine.Approved, Investigational, Nutraceutical
TriamcinoloneThe risk or severity of adverse effects can be increased when Triamcinolone is combined with Rotavirus Vaccine.Approved, Vet Approved
TriptolideThe risk or severity of adverse effects can be increased when Triptolide is combined with Rotavirus Vaccine.Investigational
TrofosfamideThe risk or severity of adverse effects can be increased when Trofosfamide is combined with Rotavirus Vaccine.Investigational
UlobetasolThe risk or severity of adverse effects can be increased when Ulobetasol is combined with Rotavirus Vaccine.Approved
UstekinumabThe risk or severity of adverse effects can be increased when Ustekinumab is combined with Rotavirus Vaccine.Approved, Investigational
VedolizumabThe risk or severity of adverse effects can be increased when Vedolizumab is combined with Rotavirus Vaccine.Approved
VeltuzumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Veltuzumab.Investigational
VilanterolThe risk or severity of adverse effects can be increased when Vilanterol is combined with Rotavirus Vaccine.Approved
VinblastineThe risk or severity of adverse effects can be increased when Vinblastine is combined with Rotavirus Vaccine.Approved
VincristineThe risk or severity of adverse effects can be increased when Vincristine is combined with Rotavirus Vaccine.Approved, Investigational
VindesineThe risk or severity of adverse effects can be increased when Vindesine is combined with Rotavirus Vaccine.Approved, Investigational
VinorelbineThe risk or severity of adverse effects can be increased when Vinorelbine is combined with Rotavirus Vaccine.Approved, Investigational
VisilizumabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Visilizumab.Investigational
VoclosporinThe risk or severity of adverse effects can be increased when Voclosporin is combined with Rotavirus Vaccine.Investigational
VolociximabThe therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with Volociximab.Investigational
WortmanninThe risk or severity of adverse effects can be increased when Wortmannin is combined with Rotavirus Vaccine.Experimental
XmAb 2513The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with XmAb 2513.Investigational
XTL-001The therapeutic efficacy of Rotavirus Vaccine can be decreased when used in combination with XTL-001.Investigational
Food Interactions
Not Available

References

General References
  1. Rotateq FDA Label [Link]
  2. CDC: About Rotavirus [Link]
External Links
PubChem Substance
347910468
ATC Codes
J07BH01 — Rota virus, live attenuated
AHFS Codes
  • 80:12.00 — Vaccines
FDA label
Download (227 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedPreventionInfections, Rotavirus1
1CompletedPreventionInfections, Rotavirus / Rotavirus Gastroenteritis2
1CompletedPreventionRotavirus Gastroenteritis1
1Not Yet RecruitingPreventionHealthy Volunteers1
1TerminatedPreventionRotavirus1
1, 2Active Not RecruitingPreventionRotavirus Gastroenteritis1
2Active Not RecruitingPreventionInfectious Diseases1
2CompletedNot AvailableDiarrhea / Fevers / Irritability / Nausea / Vomited1
2CompletedPreventionAcellular Pertussis / Diphtheria / Haemophilus Influenzae Type B / Neisseria Meningitidis / Poliomyelitis / Tetanus / Viral Hepatitis B1
2CompletedPreventionInfections, Rotavirus1
2CompletedPreventionInfections, Rotavirus / Rotavirus Gastroenteritis2
2CompletedPreventionMeningitis / Meningococcal Infections1
2CompletedPreventionRotavirus Gastroenteritis / Viral Hepatitis B1
2CompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections / Infections, Rotavirus1
2WithdrawnPreventionInfections, Rotavirus1
2, 3CompletedPreventionDiarrhea / Fevers / Irritability / Nausea / Vomited1
3Active Not RecruitingPreventionInfections, Rotavirus1
3Active Not RecruitingPreventionRotavirus Vaccines2
3Active Not RecruitingPreventionSevere Rotavirus Gastroenteritis1
3CompletedPreventionAcellular Pertussis / Diphtheria / Haemophilus Influenzae Type B / Haemophilus Influenzae Type b Diseases / Pertussis / Poliomyelitis / Tetanus1
3CompletedPreventionAcellular Pertussis / Diphtheria / Haemophilus Influenzae Type B / Poliomyelitis / Tetanus / Viral Hepatitis B1
3CompletedPreventionBacterial Infections / Neisseria Meningitidis / Virus Diseases2
3CompletedPreventionBacterial Infections / Virus Diseases4
3CompletedPreventionDiarrhea / Fevers / Vomiting1
3CompletedPreventionFevers / Infections, Rotavirus1
3CompletedPreventionGastroenteritis / Rotavirus1
3CompletedPreventionHaemophilus Influenzae Type B1
3CompletedPreventionHaemophilus Influenzae Type B / Neisseria Meningitidis1
3CompletedPreventionHealthy Volunteers / Infants / Viral Hepatitis B1
3CompletedPreventionInfections, Rotavirus3
3CompletedPreventionInfections, Rotavirus / Meningococcal Meningitis1
3CompletedPreventionInfections, Rotavirus / Pneumococcal Diseases / Streptococcus Pneumoniae Vaccines1
3CompletedPreventionInfections, Rotavirus / Rotavirus Gastroenteritis3
3CompletedPreventionInfections, Rotavirus / Rotavirus Vaccines3
3CompletedPreventionPneumococcal Diseases / Streptococcal Infections1
3CompletedPreventionRotavirus Diarrhea / Tropical Enteropathy / Vaccine Virus Shedding1
3CompletedPreventionRotavirus Gastroenteritis1
3CompletedPreventionStreptococcal Infections2
3Enrolling by InvitationPreventionInfections, Rotavirus1
4Active Not RecruitingOtherInfections, Rotavirus / Intussusception1
4Active Not RecruitingPreventionDiarrhea / Gastroenteritis1
4CompletedPreventionInfections, Rotavirus1
4CompletedPreventionInfections, Rotavirus / Rotavirus Gastroenteritis1
4CompletedPreventionIntestinal Failure / Rotavirus Vaccines1
4CompletedPreventionMeasles Antibody Seroconversion / Rotavirus GMT / Rotavirus IgA Seropositivity / Rubella Antibody Seroconversion1
4CompletedPreventionRotavirus Disease1
4CompletedPreventionRotavirus Gastroenteritis4
4CompletedPreventionRotavirus Gastroenteritis / Rotavirus Vaccines1
4CompletedPreventionRotavirus Vaccines1
4RecruitingPreventionViral Gastroenteritis Due to Rotavirus1
4Unknown StatusPreventionRotavirus1
4Unknown StatusTreatmentPoliomyelitis1
Not AvailableCompletedNot AvailableInfections, Rotavirus3
Not AvailableCompletedNot AvailableInfections, Rotavirus / Prophylaxis Against Gastroenteritis Caused by Rotavirus1
Not AvailableTerminatedNot AvailablePediatric Gastroenteritis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
Kit
SuspensionOral1000000 ccid50
SolutionOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on November 30, 2015 14:23 / Updated on June 19, 2018 10:51