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The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Synonyms: … Von willebrand factor complex (human) ... Human von willebrand factor ... Von willebrand factor (human) …
Matched Name: … Von Willebrand factor human
Matched Description: … The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma ... [L40049] As vWF is normally present in the blood as a stable complex with coagulation factor III, therapeutic ... The human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease …
Matched Mixtures name: … von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... Wilate - von Willebrand Factor/Coagulation Factor VIII Complex (Human) …
Matched Categories: … von Willebrand factor and coagulation factor VIII in combination ... von Willebrand Factor ... von Willebrand factor ... von Willebrand Factor, antagonists & inhibitors ... Blood Coagulation Factors …
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Synonyms: … Coagulation factor VIIa ... Coagulation factor VIIa (recombinant) ... Coagulation factor VIIa (recombinant)-jncw …
Matched Name: … Coagulation factor VIIa Recombinant Human
Matched Description: … Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the ... extrinsic pathway of the coagulation cascade. …
Matched Categories: … coagulation factor VIIa ... Increased Coagulation Factor X Activity ... Increased Coagulation Factor IX Activity ... Blood Coagulation Factors ... Factor VII …
Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation cascade [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key...
Approved
Investigational
Matched Synonyms: … Human coagulation factor XIII ... Coagulation factor XIII, recombinant ... Factor XIII, human
Matched Name: … Factor XIII (human) …
Matched Description: … Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous ... is a recombinant form of the A subunit of human coagulation factor XIII. ... Also known as Fibrin Stabilizing Factor (FSF), Factor XIII is an endogenously produced coagulation factor
Matched Categories: … Factor XIIIa, antagonists & inhibitors ... Blood Coagulation Factors ... Increased Coagulation Activity …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … Human coagulation factor VIII ... factor VIII, human ... Factor VIII (human) …
Matched Name: … Antihemophilic factor human
Matched Description: … Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) ... Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is ... The small amount of VWF:Ag is used to purify factor VIII complex and then removed from the final preparation …
Matched Mixtures name: … von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... Wilate - von Willebrand Factor/Coagulation Factor VIII Complex (Human) …
Matched Categories: … coagulation factor VIII ... Factor VIII ... Human Antihemophilic Factors ... Blood Coagulation Factors ... Increased Coagulation Activity …
Matched Products: … FACTOR VIII 500 IU FLAKON, 1 ADET ... FAKTOR VIII 8Y 500 IU IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Synonyms: … Coagulation factor IX (human) ... Human coagulation factor IX ... Factor IX (Human) …
Matched Name: … Coagulation Factor IX Human
Matched Description: … Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs …
Matched Mixtures name: … UMAN COMPLEX ... UMAN COMPLEX ... UMAN COMPLEX
Matched Categories: … coagulation factor IX ... coagulation factor IX, II, VII and X in combination ... Factor IX ... Blood Coagulation Factors ... Increased Coagulation Activity …
Matched Products: … REPLENINE VF (HIGH PURITY FACTOR IX) …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX complex human ... Factor IX complex human ... Factor IX complex,human
Matched Name: … Factor IX Complex (Human) …
Matched Description: … Although Factor IX Complex products contain many different coagulation components, Factor IX is the ... As the product Kcentra, Factor IX Complex is also indicated for the urgent reversal of acquired coagulation ... Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. …
Matched Categories: … Factor IX ... Blood Coagulation Factors …
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Synonyms: … Coagulation factor X (human) ... Human coagulation factor X ... Coagulation factor X …
Matched Name: … Coagulation factor X human
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... Coagulation Factor X (Human) solution is approved by the FDA for intravenous injection under the market ... Coagulation Factor X is a vitamin K-dependent, liver-produced serine protease that serves as the first …
Matched Mixtures name: … UMAN COMPLEX ... UMAN COMPLEX ... UMAN COMPLEX
Matched Categories: … coagulation factor X ... Factor X ... Factor X, agonists ... Blood Coagulation Factors ... Increased Coagulation Activity …
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Synonyms: … Coagulation Factor I ... Factor I human ... Factor I (fibrinogen) …
Matched Name: … Fibrinogen human
Matched Description: … Fibrinogen concentrate (human) is a hematological agent. ... It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. …
Matched Mixtures name: … EVICEL Fibrin Sealant (Human) ... EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml …
Matched Categories: … fibrinogen, human ... Blood Coagulation Factors ... Increased Coagulation Activity …
Approved
Investigational
Matched Synonyms: … Factor VIII
Matched Categories: … Factor VIII ... Blood Coagulation Factors ... Human Antihemophilic Factors …
Matched Products: … DRIED FACTOR VIII FRACTION 500 UI + FACTOR DE VON WILLEBRAND 800 UI ... DRIED FACTOR VIII ... HEMOFIL M ANTIHEMOPHILIC FACTOR (HUMAN), METHOD M, …
Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Approved
Investigational
Matched Synonyms: … Coagulation factor VII (human) ... Human coagulation factor VII ... Factor VII human
Matched Name: … Coagulation factor VII human
Matched Description: … Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation
Matched Mixtures name: … UMAN COMPLEX ... UMAN COMPLEX
Matched Categories: … coagulation factor VII ... coagulation factor IX, II, VII and X in combination ... Blood Coagulation Factors ... Increased Coagulation Activity …
Matched Products: … CONCENTRADO DE FACTOR VII …
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying …
Matched Description: … coagulation factor VIII (hFVIII-SQ). ... factor VIII. ... VIII protein and increase the levels of active factor VIII in blood. …
Matched Categories: … Blood Coagulation Factors …
Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Synonyms: … Coagulation factor VIII, recombinant ... Human factor VIII recombinant ... Human Factor VIII (Recombinant) …
Matched Name: … Antihemophilic factor, human recombinant …
Matched Description: … Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by …
Matched Categories: … coagulation factor VIII ... Human Antihemophilic Factors ... Blood Coagulation Factors ... Increased Coagulation Activity …
Matched Products: … GREEN VIII LYOPHILIZED® 250UI ... KOGENATE® FS FACTOR ANTIHEMOFILICORECOMBINANTE250 UI. FORMULADO CON SUCROSA ... KOGENATE® FS FACTOR ANTIHEMOFILICORECOMBINANTE1000 UI. FORMULADO CON SUCROSA …
Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This transformation mimics the final coagulation cascade step which involves the clotting mass...
Approved
Matched Synonyms: … Thrombin human ... Thrombin (human) ... Thrombin Human Plasma-derived …
Matched Name: … Human thrombin …
Matched Description: … is a human coagulation protein produced via recombinant DNA technology from a genetically modified Chinese ... This transformation mimics the final coagulation cascade step which involves the clotting mass that adheres ... Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation …
Matched Mixtures name: … EVICEL Fibrin Sealant (Human) ... EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml …
Matched Categories: … Increased Coagulation Factor Activity ... Blood Coagulation Factors …
Matched Products: … Thrombin Human
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Coagulation factor VIII recombinant immunoglubulin g1 fusion protein ... Antihemophilic factor (recombinant, FC fusion protein) ... Antihemophilic Factor (Recombinant BDD), FC Fusion Protein …
Matched Description: … is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... The B domain of factor VIII is deleted. ... Factor VIII is a blood coagulant factor involved in the intrinsic pathway to form fibrin, or a blood …
Matched Categories: … Human Antihemophilic Factors …
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … CELLS: DES-(753-1418)-BLOOD-COAGULATION FACTOR VIII (PROCOAGULANT COMPONENT) SUS SCROFA, GLYCOSYLATED ... Porcine recombinant factor VIII B-domain truncated ... RECOMBINANT DNA DERIVED B-DOMAIN DELETED PORCINE BLOODCOAGULATION FACTOR VIII ANALOGUE, PRODUCED IN BHK21 …
Matched Description: … Patients with AHA have normal Factor VIII genes for coagulation pathways but develop inhibitory autoantibodies ... These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... directed against Factor VIII. …
Matched Categories: … Blood Coagulation Factors …
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Synonyms: … Human factor VIII, recombinant B-domain deleted ... B-domain deleted recombinant factor VIII ... Antihemphilic factor, recombinant human B-domain deleted …
Matched Description: … As it does not contain von Willebrand factor it is not indicated in von Willebrand’s disease [FDA Label ... Congenital loss or deficiency of Factor VIII results in the physiologic impairment of the coagulation ... DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor
Matched Categories: … Blood Coagulation Factors …
Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX recombinant human ... Coagulation factor IX (recombinant) ... Coagulation factor IX, recombinant …
Matched Name: … Coagulation Factor IX (Recombinant) …
Matched Description: … It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Matched Categories: … Blood Coagulation Factors ... Increased Coagulation Activity …
Matched Products: … CONCENTRADO DE FACTOR IX …
Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Matched Synonyms: … Calcitonin human ... Calcitonin (human) ... Calcitonin, human
Matched Name: … Human calcitonin …
Matched Categories: … calcitonin (human synthetic) …
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019. Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Synonyms: … Antihemophilic factor (recombinant), glycopegylated-exei …
Matched Description: … VIII molecule for factor VIII replacement therapy in patients with factor VIII deficiency, or hemophilia ... Fundamentally, the N8-GP moiety is identical to [turoctocog alfa], a recombinant human clotting factor ... Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any human or animal-derived …
Matched Categories: … Factor VIII ... Blood Coagulation Factors …
Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot. Medical thrombin is a protein substance produced...
Approved
Investigational
Matched Synonyms: … coagulation factor II …
Matched Description: … These antibodies may subsequently cross-react with endogenous human factor V and lead to its deficiency ... Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in ... regulating hemostasis and maintaining blood coagulation. …
Matched Categories: … Increased Coagulation Factor Activity ... Blood Coagulation Factors …
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Synonyms: … Antithrombin III (human) ... Antithrombin III human ... Antithrombin III,human
Matched Name: … Antithrombin III human
Matched Categories: … Blood Coagulation Factor Inhibitors …
Nonacog beta pegol is a recombinant coagulation factor IX derivative. It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa). Nonacog...
Approved
Investigational
Matched Synonyms: … Coagulation Factor IX (Recombinant), GlycoPEGylated …
Matched Description: … Nonacog beta pegol is a recombinant coagulation factor IX derivative. ... Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor
Matched Categories: … Blood Coagulation Factors …
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Synonyms: … Human IGG ... Human gammaglobulin ... Human immunoglobulin G …
Matched Name: … Human immunoglobulin G …
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population …
Matched Categories: … Human Immunoglobulin G …
Matched Products: … Octagam Immune Globulin (Human) ... Immune Serum Globulin (human) ... Immune Globulin Intravenous (human) 5% …
Approved
Matched Name: … Undecoylium chloride iodine complex
Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Synonyms: … Human chorionic gonadotropin ... Human menopausal gonadotropin ... Human-chorionic gonadotropin …
Matched Name: … Chorionic Gonadotropin (Human) …
Matched Description: … Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. ... The alpha sub-unit is essentially identical to the alpha sub­ units of the human pituitary gonadotropins ... luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as to the alpha sub-unit of human
Matched Categories: … Complex Mixtures …
Matched Products: … Human Chorionic Gonadotrophin …
Displaying drugs 1 - 25 of 2879 in total