Displaying drugs 301 - 325 of 11299 in total
Tyloxapol
Tyloxapol is a non-ionic detergent often used as a surfactant.
Approved
Investigational
Matched Description: … Tyloxapol is a non-ionic detergent often used as a surfactant. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Pentastarch
Pentastarch is an artificial colloid (hydroxyethyl starch derivative). Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation. It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. When administered, pentastarch remains mainly in the circulatory system and hence, it...
Approved
Investigational
Matched Description: … When administered, pentastarch remains mainly in the circulatory system and hence, it is considered a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Boric acid
Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and eyewashes . It...
Approved
Matched Description: … Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Indocyanine green acid form
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Description: … Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. ... Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. ... Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Methylprednisone
Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Approved
Investigational
Matched Iupac: … hydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Aclidinium
Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Approved
Matched Description: … It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. …
Cetrorelix
Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational
Matched Description: … Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). …
Almotriptan
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Description: … Almotriptan is a triptan drug for the treatment of migraine headaches. ... Almotriptan is in a class of medications called selective serotonin receptor agonists. …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Categories: … Monoamine Oxidase A Substrates …
Zidovudine
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Description: … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during ... A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced …
Matched Mixtures name: … N/A …
Matched Mixtures name: … N/A …
Pegaptanib
Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability.
Pegaptanib was granted FDA approval on 17 September 2004.
Approved
Investigational
Matched Description: … Pegaptanib is a polynucleotide aptamer. …
Matched Categories: … Vascular Endothelial Growth Factor A …
Matched Categories: … Vascular Endothelial Growth Factor A …
Perflubutane
Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress testing; currently the leading procedure for detecting coronary heart disease.
Approved
Investigational
Matched Description: … It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Indocyanine green
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Etonogestrel
Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.
Approved
Investigational
Matched Iupac: … -1-ethynyl-1-hydroxy-10-methylidene-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically …
Matched Description: … Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically …
Ethynodiol diacetate
A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Iupac: … -7-(acetyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually …
Matched Description: … A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually …
Norgestimate
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Iupac: … 11a-ethyl-1-ethynyl-7-(hydroxyimino)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … [A191068] It is commonly formulated with [ethinylestradiol] as a combined oral contraceptive that can …
Matched Description: … [A191068] It is commonly formulated with [ethinylestradiol] as a combined oral contraceptive that can …
Sucrose
A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Approved
Experimental
Investigational
Matched Description: … food and a sweetener. ... A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. ... obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Hydroxyprogesterone caproate
Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug...
Approved
Investigational
Matched Iupac: … 11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … history of preterm delivery, sparking a pricing controversy. ... Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate ... (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a …
Matched Description: … history of preterm delivery, sparking a pricing controversy. ... Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate ... (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a …
Technetium Tc-99m pertechnetate
Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … a similar extent as iodine. ... This is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby ... Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Moxidectin
Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of...
Approved
Investigational
Vet approved
Matched Description: … It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of ... Moxidectin differs by the absence of a disaccharide moiety on carbon 13, a substituted olefinic side ... chain at carbon 25 and a unique methoxime moiety at carbon 23. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Gadobutrol
Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is
formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Description: … Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast ... fibrosis (NSF) due to the dissociation of gadolinium from the chelates, although gadobutrol tends to have a ... gadobutrol is
formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Polyethylene glycol 400
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … a low-level toxicity. ... In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788 ... [L1787]
Polyethylene glycol 400 (PEG 400) is a low-molecular-weight grade of polyethylene glycol with …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ambenonium
Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis.
Approved
Matched Description: … Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis. …
Macimorelin
Macimorelin, a novel and orally active ghrelin mimetic that stimulates GH secretion, is used in the diagnosis of adult GH deficiency (AGHD). More specifically, macimorelin is a peptidomimetic growth hormone secretagogue (GHS) that acts as an agonist of GH secretagogue receptor, or ghrelin receptor (GHS-R1a) to dose-dependently increase GH levels...
Approved
Investigational
Matched Description: … More specifically, macimorelin is a peptidomimetic growth hormone secretagogue (GHS) that acts as an ... Macimorelin, a novel and orally active ghrelin mimetic that stimulates GH secretion, is used in the diagnosis ... Risk factors of AGHD include a history of childhood-onset GH deficiency or with hypothalamic/pituitary …
Bulevirtide
Hepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development of cirrhosis, severe decompensation of liver function, and an increased risk of mortality.[A226340,L30235] Until recently, there have been extremely limited treatments available for Hepatitis D infection. Bulevirtide, also known as Hepcludex, is a...
Approved
Investigational
Matched Description: … [A226305]
Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment …
Alogliptin
Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase ... Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Displaying drugs 301 - 325 of 11299 in total