Identification
NameSucrose
Accession NumberDB02772  (EXPT02977)
TypeSmall Molecule
GroupsExperimental
Description

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener. [PubChem]

Structure
Thumb
SynonymsNot Available
External IDs GNE-410 / NSC-406942 / S-67F
Product Ingredients Not Available
Approved Prescription ProductsNot Available
Approved Generic Prescription ProductsNot Available
Approved Over the Counter ProductsNot Available
Unapproved/Other Products Not Available
International BrandsNot Available
Brand mixtures
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Childrens Emetrol Dye Free GrapeSolutionOralWell Spring Pharmaceutical Corporation2013-04-212016-09-30Us
Emetrol CherrySolutionOralPreferreed Pharmaceuticals Inc.2012-04-23Not applicableUs
Select Brand Anti-NauseaSolutionOralSelect Brands Distributors2008-01-01Not applicableUs
Categories
UNIIC151H8M554
CAS number57-50-1
WeightAverage: 342.2965
Monoisotopic: 342.116211546
Chemical FormulaC12H22O11
InChI KeyCZMRCDWAGMRECN-UGDNZRGBSA-N
InChI
InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
IUPAC Name
(2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES
OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O
Pharmacology
IndicationNot Available
Structured Indications Not Available
PharmacodynamicsNot Available
Mechanism of action
TargetKindPharmacological actionActionsOrganismUniProt ID
Beta-lactamaseProteinunknownNot AvailableEscherichia coli (strain K12)P00811 details
Nitric oxide synthase oxygenaseProteinunknownNot AvailableStaphylococcus aureus (strain MW2)P0A094 details
Lysozyme CProteinunknownNot AvailableHumanP61626 details
Septum formation protein MafProteinunknownNot AvailableBacillus subtilis (strain 168)Q02169 details
GDP-mannose 6-dehydrogenaseProteinunknownNot AvailablePseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)P11759 details
Actin, alpha skeletal muscleProteinunknownNot AvailableHumanP68133 details
Beta-glucosidaseProteinunknownNot AvailableStreptomyces sp.Q59976 details
AmylosucraseProteinunknownNot AvailableNeisseria polysacchareaQ9ZEU2 details
Beta-lactamaseProteinunknownNot AvailableEscherichia coliQ9L5C8 details
Beta-lactamase CTX-MProteinunknownNot AvailableEscherichia coliQ9L5C7 details
Heme oxygenaseProteinunknownNot AvailableCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)P71119 details
Copper transport protein ATOX1ProteinunknownNot AvailableHumanO00244 details
tRNA-splicing ligase RtcB homologProteinunknownNot AvailableHumanQ9Y3I0 details
Orange carotenoid-binding proteinProteinunknownNot AvailableArthrospira maximaP83689 details
Sucrose porinProteinunknownNot AvailableSalmonella typhimuriumP22340 details
LevansucraseProteinunknownNot AvailableBacillus subtilis (strain 168)P05655 details
Beta-lactamase CTX-M-27ProteinunknownNot AvailableEscherichia coliQ840M4 details
Taste receptor type 1 member 2ProteinunknownNot AvailableHumanQ8TE23 details
Related Articles
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationNot Available
Half lifeNot Available
ClearanceNot Available
ToxicityNot Available
Affected organismsNot Available
PathwaysNot Available
Pharmacogenomic Effects/ADRs Not Available
Interactions
Drug Interactions Not Available
Food InteractionsNot Available
References
Synthesis Reference

Francois B. Paul, Pierre F. Monsan, Magali M. C. Remaud, Vincent P. Pelenc, "Process for the enzymatic preparation from sucrose of a mixture of sugars having a high content of isomaltose, and products obtained." U.S. Patent US4861381, issued April, 1956.

US4861381
General References
  1. Ten S, Maclaren N: Insulin resistance syndrome in children. J Clin Endocrinol Metab. 2004 Jun;89(6):2526-39. [PubMed:15181020 ]
  2. Aguilera AA, Diaz GH, Barcelata ML, Guerrero OA, Ros RM: Effects of fish oil on hypertension, plasma lipids, and tumor necrosis factor-alpha in rats with sucrose-induced metabolic syndrome. J Nutr Biochem. 2004 Jun;15(6):350-7. [PubMed:15157941 ]
  3. Fukuchi S, Hamaguchi K, Seike M, Himeno K, Sakata T, Yoshimatsu H: Role of fatty acid composition in the development of metabolic disorders in sucrose-induced obese rats. Exp Biol Med (Maywood). 2004 Jun;229(6):486-93. [PubMed:15169967 ]
  4. Lombardo YB, Drago S, Chicco A, Fainstein-Day P, Gutman R, Gagliardino JJ, Gomez Dumm CL: Long-term administration of a sucrose-rich diet to normal rats: relationship between metabolic and hormonal profiles and morphological changes in the endocrine pancreas. Metabolism. 1996 Dec;45(12):1527-32. [PubMed:8969287 ]
External Links
ATC CodesNot Available
AHFS CodesNot Available
PDB Entries
FDA labelNot Available
MSDSNot Available
Clinical Trials
Clinical Trials
PhaseStatusPurposeConditionsCount
1, 2Active Not RecruitingTreatmentCongestive Heart Failure (CHF)1
1, 2CompletedPreventionAcute Gastroenteritis / Norwalk Virus Infection1
1, 2CompletedTreatmentRetinopathy of Prematurity1
2CompletedNot AvailableInfants, Premature1
2CompletedTreatmentPain1
2, 3CompletedTreatmentPain in Preterm Neonates1
3CompletedScreeningPain1
3CompletedSupportive CareAnalgesia1
3CompletedTreatmentELBW / Neonates / Pain1
3CompletedTreatmentOccasional Constipation1
3CompletedTreatmentPain1
3RecruitingSupportive CarePain1
3Unknown StatusTreatmentVaccination Pain Management1
4CompletedPreventionInfections, Pneumococcal / Thalassaemic disorders1
4CompletedTreatmentProcedural Pain1
4RecruitingTreatmentPain Due to Certain Specified Procedures1
Not AvailableCompletedTreatmentPain1
Not AvailableCompletedTreatmentRetinopathy of Prematurity1
Not AvailableRecruitingPreventionMemory Disturbances1
Not AvailableTerminatedTreatmentInfants, Premature / Retinal Disorders1
Not AvailableUnknown StatusPreventionDevelopment1
Not AvailableUnknown StatusTreatmentDiabetes / Newborn Infants / Pain1
Pharmacoeconomics
ManufacturersNot Available
PackagersNot Available
Dosage forms
FormRouteStrength
SolutionOral
PricesNot Available
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point (°C)185.5 °CPhysProp
water solubility2.1E+006 mg/L (at 25 °C)YALKOWSKY,SH & DANNENFELSER,RM (1992)
logP-3.70HANSCH,C ET AL. (1995)
Caco2 permeability-5.77ADME Research, USCD
pKa12.6MERCK INDEX (1996)
Predicted Properties
PropertyValueSource
Water Solubility824.0 mg/mLALOGPS
logP-2.6ALOGPS
logP-4.5ChemAxon
logS0.38ALOGPS
pKa (Strongest Acidic)11.84ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count11ChemAxon
Hydrogen Donor Count8ChemAxon
Polar Surface Area189.53 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity68.77 m3·mol-1ChemAxon
Polarizability31.03 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability0ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption-0.8682
Blood Brain Barrier+0.7245
Caco-2 permeable-0.8957
P-glycoprotein substrateNon-substrate0.6386
P-glycoprotein inhibitor INon-inhibitor0.8721
P-glycoprotein inhibitor IINon-inhibitor0.9402
Renal organic cation transporterNon-inhibitor0.8146
CYP450 2C9 substrateNon-substrate0.8747
CYP450 2D6 substrateNon-substrate0.8561
CYP450 3A4 substrateNon-substrate0.6536
CYP450 1A2 substrateNon-inhibitor0.9425
CYP450 2C9 inhibitorNon-inhibitor0.9377
CYP450 2D6 inhibitorNon-inhibitor0.9395
CYP450 2C19 inhibitorNon-inhibitor0.8821
CYP450 3A4 inhibitorNon-inhibitor0.9716
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9258
Ames testNon AMES toxic0.9132
CarcinogenicityNon-carcinogens0.9565
BiodegradationNot ready biodegradable0.7256
Rat acute toxicity1.0936 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9633
hERG inhibition (predictor II)Non-inhibitor0.883
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (8 TMS)splash10-0gba-0930000000-594ae5d59d217235e6c7View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)splash10-02ta-0932000000-8fa2c23f886fb0c63312View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (8 TMS)splash10-00di-9731000000-0d702b863a0419bd559cView in MoNA
Predicted GC-MSPredicted GC-MS Spectrum - GC-MSNot Available
GC-MSGC-MS Spectrum - GC-EI-TOFsplash10-0gba-0930000000-594ae5d59d217235e6c7View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOFsplash10-02ta-0932000000-8fa2c23f886fb0c63312View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOFsplash10-00di-9731000000-0d702b863a0419bd559cView in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOFsplash10-0i01-0932000000-a84ab9868385a177391aView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-03di-0900000000-1ba130720abffe5e93d0View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-002r-9600000000-bf4df12e3ec24b4de57bView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-000i-9100000000-5308faa0508d0796ef2cView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negativesplash10-0fdx-9804000000-018a029ba3843a8db2bdView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF , negativesplash10-0fdx-9804000000-018a029ba3843a8db2bdView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, NegativeNot Available
MSMass Spectrum (Electron Ionization)splash10-05dm-9100000000-ff1c60103a4253a94cf7View in MoNA
1D NMR13C NMR SpectrumNot Available
1D NMR1H NMR SpectrumNot Available
1D NMR1H NMR SpectrumNot Available
1D NMR13C NMR SpectrumNot Available
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,1H] 2D NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond.
KingdomOrganic compounds
Super ClassOrganic oxygen compounds
ClassOrganooxygen compounds
Sub ClassCarbohydrates and carbohydrate conjugates
Direct ParentO-glycosyl compounds
Alternative ParentsDisaccharides / C-glycosyl compounds / Ketals / Oxanes / Tetrahydrofurans / Secondary alcohols / Polyols / Oxacyclic compounds / Primary alcohols / Hydrocarbon derivatives
SubstituentsO-glycosyl compound / Disaccharide / C-glycosyl compound / Ketal / Oxane / Tetrahydrofuran / Secondary alcohol / Oxacycle / Organoheterocyclic compound / Polyol
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptorsglycosyl glycoside (CHEBI:17992 ) / Disaccharides (C00089 )

Targets

Kind
Protein
Organism
Escherichia coli (strain K12)
Pharmacological action
unknown
General Function:
Beta-lactamase activity
Specific Function:
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
Gene Name:
ampC
Uniprot ID:
P00811
Uniprot Name:
Beta-lactamase
Molecular Weight:
41555.3 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Staphylococcus aureus (strain MW2)
Pharmacological action
unknown
General Function:
Nitric-oxide synthase activity
Specific Function:
Catalyzes the production of nitric oxide.
Gene Name:
nos
Uniprot ID:
P0A094
Uniprot Name:
Nitric oxide synthase oxygenase
Molecular Weight:
41709.935 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Lysozyme activity
Specific Function:
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
Gene Name:
LYZ
Uniprot ID:
P61626
Uniprot Name:
Lysozyme C
Molecular Weight:
16536.885 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [PubMed:10592235 ]
Kind
Protein
Organism
Bacillus subtilis (strain 168)
Pharmacological action
unknown
General Function:
Not Available
Specific Function:
Involved in septum formation.
Gene Name:
maf
Uniprot ID:
Q02169
Uniprot Name:
Septum formation protein Maf
Molecular Weight:
21295.18 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pharmacological action
unknown
General Function:
Udp-glucose 6-dehydrogenase activity
Specific Function:
Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics.
Gene Name:
algD
Uniprot ID:
P11759
Uniprot Name:
GDP-mannose 6-dehydrogenase
Molecular Weight:
47599.155 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Structural constituent of cytoskeleton
Specific Function:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Gene Name:
ACTA1
Uniprot ID:
P68133
Uniprot Name:
Actin, alpha skeletal muscle
Molecular Weight:
42050.67 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [PubMed:10592235 ]
Kind
Protein
Organism
Streptomyces sp.
Pharmacological action
unknown
General Function:
Beta-glucosidase activity
Specific Function:
Not Available
Gene Name:
bgl3
Uniprot ID:
Q59976
Uniprot Name:
Beta-glucosidase
Molecular Weight:
52382.78 Da
Kind
Protein
Organism
Neisseria polysaccharea
Pharmacological action
unknown
General Function:
Cation binding
Specific Function:
Catalyzes the synthesis of alpha-glucan from sucrose. Catalyzes, in addition, sucrose hydrolysis, maltose and maltotriose synthesis by successive transfers of the glucosyl moiety of sucrose onto the released glucose, and finally turanose and trehalulose synthesis, these two sucrose isomers being obtained by glucosyl transfer onto fructose.
Gene Name:
ams
Uniprot ID:
Q9ZEU2
Uniprot Name:
Amylosucrase
Molecular Weight:
72343.005 Da
Kind
Protein
Organism
Escherichia coli
Pharmacological action
unknown
General Function:
Beta-lactamase activity
Specific Function:
Not Available
Gene Name:
blaCTX-M-9a
Uniprot ID:
Q9L5C8
Uniprot Name:
Beta-lactamase
Molecular Weight:
30951.03 Da
Kind
Protein
Organism
Escherichia coli
Pharmacological action
unknown
General Function:
Not Available
Specific Function:
Beta-lactamase activity
Gene Name:
blaCTX-M-14
Uniprot ID:
Q9L5C7
Uniprot Name:
Beta-lactamase
Molecular Weight:
30979.09 Da
Kind
Protein
Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Pharmacological action
unknown
General Function:
Metal ion binding
Specific Function:
Allows the bacteria to use the host heme as an iron source. Involved in the oxidation of heme and subsequent release of iron from the heme moiety.
Gene Name:
hmuO
Uniprot ID:
P71119
Uniprot Name:
Heme oxygenase
Molecular Weight:
24115.81 Da
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Metallochaperone activity
Specific Function:
Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.
Gene Name:
ATOX1
Uniprot ID:
O00244
Uniprot Name:
Copper transport protein ATOX1
Molecular Weight:
7401.575 Da
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Vinculin binding
Specific Function:
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
Gene Name:
RTCB
Uniprot ID:
Q9Y3I0
Uniprot Name:
tRNA-splicing ligase RtcB homolog
Molecular Weight:
55209.95 Da
References
  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [PubMed:10592235 ]
Kind
Protein
Organism
Arthrospira maxima
Pharmacological action
unknown
General Function:
Photoreceptor activity
Specific Function:
Acts as a blue-light photoreceptor and photo-protectant. Essential for inhibiting damaged induced by excess blue-green light via a process known as non-photochemical quenching (NPQ). Binding carotenoids improves OCP's intrinsic photoprotectant activity by broadening its absorption spectrum and facilitating the dissipation of absorbed energy (PubMed:15751975). In the dark or dim light the stable...
Gene Name:
Not Available
Uniprot ID:
P83689
Uniprot Name:
Orange carotenoid-binding protein
Molecular Weight:
35347.29 Da
Kind
Protein
Organism
Salmonella typhimurium
Pharmacological action
unknown
General Function:
Porin activity
Specific Function:
Porin for sucrose uptake.
Gene Name:
scrY
Uniprot ID:
P22340
Uniprot Name:
Sucrose porin
Molecular Weight:
55466.87 Da
Kind
Protein
Organism
Bacillus subtilis (strain 168)
Pharmacological action
unknown
General Function:
Levansucrase activity
Specific Function:
Not Available
Gene Name:
sacB
Uniprot ID:
P05655
Uniprot Name:
Levansucrase
Molecular Weight:
52970.73 Da
Kind
Protein
Organism
Escherichia coli
Pharmacological action
unknown
General Function:
Not Available
Specific Function:
Beta-lactamase activity
Gene Name:
blaCTX-M-27
Uniprot ID:
Q840M4
Uniprot Name:
Beta-lactamase
Molecular Weight:
30921.06 Da
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Taste receptor activity
Specific Function:
Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.
Gene Name:
TAS1R2
Uniprot ID:
Q8TE23
Uniprot Name:
Taste receptor type 1 member 2
Molecular Weight:
95182.54 Da
References
  1. Servant G, Tachdjian C, Tang XQ, Werner S, Zhang F, Li X, Kamdar P, Petrovic G, Ditschun T, Java A, Brust P, Brune N, DuBois GE, Zoller M, Karanewsky DS: Positive allosteric modulators of the human sweet taste receptor enhance sweet taste. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4746-51. doi: 10.1073/pnas.0911670107. Epub 2010 Feb 19. [PubMed:20173092 ]
Drug created on June 13, 2005 07:24 / Updated on September 01, 2017 10:56