Displaying drugs 3726 - 3750 of 11847 in total
Ranitidine
Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Description: … Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to …
Eleuthero
Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. …
Trospium
Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. Trospium is manufactured by Indevus Pharmaceutical Inc. and...
Approved
Matched Description: … Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that …
Lipegfilgrastim
Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational
Matched Description: … Lipegfilgrastim is a covalent conjugate of [DB00099] with a single methoxy polyethylene glycol (PEG) ... Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating ... factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology [A32665] …
Vortioxetine
Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake...
Approved
Investigational
Matched Description: … It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action ... More specifically, vortioxetine acts via the following biological mechanisms: as a serotonin reuptake ... inhibitor (SRI) through inhibition of the serotonin transporter, as a partial agonist of the 5-HT1B …
Rabies virus inactivated antigen, B
Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Diaminopropanol tetraacetic acid
Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others.
Approved
Investigational
Telotristat ethyl
Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo. It was previously referred to as telotristat etiprate, the hippurate salt form; however, the FDA recommends the use of the name of the neutral form rather than that of the salt.[A252937, A252942]...
Approved
Investigational
Matched Description: … Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo. ... can therefore secrete chemical mediators into the bloodstream to cause side effects in distant sites, a …
Melopsittacus undulatus feather
Melopsittacus undulatus feather is used in allergenic testing.
Approved
Ustekinumab
Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice. It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that...
Approved
Investigational
Matched Description: … Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin( ... [A187349] It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that is used in the …
Omidenepag isopropyl
Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Description: … Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) ... [L43503] Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule …
Fluoride ion F-18
Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. It contains radioactive fluoride F 18 that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging and is administered by intravenous injection. Its primary indication is for bone imaging. Increased deposition around joints can...
Approved
Matched Description: … Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. …
Tinidazole
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Approved
Investigational
Matched Description: … A nitroimidazole antitrichomonal agent effective against _Trichomonas vaginalis_, _Entamoeba histolytica …
Lodoxamide
Lodoxamide is a mast-cell stabilizer for topical administration into the eye. Mast-cell stabilizers, first one approved being cromolyn sodium, are used in treatment of ocular hypersensitivity reactions such as vernal conjunctivitis. These conditions often require treatment with anti-inflammatory medications such as ophthalmic NSAIDs or topical steroids which may cause systemic...
Approved
Matched Description: … Lodoxamide is a mast-cell stabilizer for topical administration into the eye. …
1,2-icosapentoyl-sn-glycero-3-phosphoserine
Approved
Experimental
Bismuth subcitrate potassium
A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Approved
Investigational
Matched Description: … A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD). …
Aluminum chlorohydrex propylene glycol
Aluminum chlorohydrex propylene glycol is a complex consisting of Aluminum Chorohydrate and propylene glycol (PG). It is an antiperspirant active ingredient found in antiperspirant drug products for over-the-counter human use.
Approved
Matched Description: … Aluminum chlorohydrex propylene glycol is a complex consisting of Aluminum Chorohydrate and propylene …
Laronidase
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Description: … Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. ... polymorphic form of human a-L-iduronidase. ... recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a …
Saw palmetto
Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Description: … Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. …
Ferric pyrophosphate citrate
Ferric pyrophosphate citrate is a soluble iron replacement product. Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. The ferric ion is strongly complexed by pyrophosphate and citrate. FPC is categorized in...
Approved
Investigational
Matched Description: … Ferric pyrophosphate citrate is a soluble iron replacement product. ... [A31979] FPC is categorized in Japan as a second class OTC drug. …
Eletriptan
Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Approved
Investigational
Matched Description: … Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine …
Pinacidil
Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood pressure. This drug has been discontinued by the FDA.
Approved
Matched Description: … Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to …
Isatuximab
Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line.[L12099,A191799] Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and two identical immunoglobulin gamma heavy chains. It is a cytolytic antibody targeted against CD38, a glycoprotein found on the...
Approved
Investigational
Matched Description: … [L12099] It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some ... a Chinese hamster ovary (CHO) cell line. ... Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from …
Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. …
Pegademase
Bovine adenosine deaminase derived from bovine intestine that has been extensively pegylated for extended serum half life.
Approved
Displaying drugs 3726 - 3750 of 11847 in total