Displaying drugs 4326 - 4350 of 11286 in total
Tanespimycin
Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90). It is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia.
Investigational
Matched Description: … of heat shock protein 90 (HSP90). ... Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Retaspimycin
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
CEP-1347
CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and after transplantation.
Investigational
Matched Description: … CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults …
AG-702
AG-702 is a recombinant human heat shock protein also known as stress protein. It is also known as HSPs, which are a group of proteins that are induced when a cell undergoes various types of environmental stresses like heat, cold and oxygen deprivation. HSPs are present in all cells in...
Investigational
Matched Description: … AG-702 is a recombinant human heat shock protein also known as stress protein. ... It is also known as HSPs, which are a group of proteins that are induced when a cell undergoes various ... types of environmental stresses like heat, cold and oxygen deprivation. …
Marstacimab
Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and hemophilia B.
Investigational
Matched Description: … being developed by Pfizer for the treatment of hemophilia A and hemophilia B. ... Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently …
XL-888
XL888 has been used in trials studying the treatment of Cancer and Melanoma.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Clomethiazole
Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. It...
Investigational
Matched Description: … It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic ... Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. ... It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
AUY922
AUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Tea tree oil
Tea tree oil is an essential oil derived mainly from the Australian native plant Melaleuca alternifolia via steam distillation of the of the leaves and terminal branches . It may be referred to as Melaleuca alternifolia oil. It has been a popular ingredient in a variety of household and cosmetic...
Experimental
Nutraceutical
Matched Description: … It has been a popular ingredient in a variety of household and cosmetic products due to its antiseptic …
Matched Mixtures name: … Muscle and Joint Heat Cream …
Matched Mixtures name: … Muscle and Joint Heat Cream …
Pentetrazol
Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) receptor antagonist that was approved by the FDA until 1982.
Experimental
Withdrawn
Matched Iupac: … 5H,6H,7H,8H,9H-[1,2,3,4]tetrazolo[1,5-a]azepine …
Matched Description: … Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) …
Matched Description: … Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) …
Lecithin
A complex mixture of phospholipids, glycolipids, triglycerides, phosphatidylcholines, phosphatidylethanolamines, and phosphatidylinositols.
Experimental
Matched Description: … A complex mixture of phospholipids, glycolipids, triglycerides, phosphatidylcholines, phosphatidylethanolamines …
Matched Mixtures name: … ONE A DAY TABLET …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … ONE A DAY TABLET …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dibromothymoquinone
At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem]
Experimental
Matched Description: … this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a …
PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE
Experimental
Matched Iupac: … 4-{[6-(2,6-dichlorobenzoyl)imidazo[1,2-a]pyridin-2-yl]amino}benzene-1-sulfonamide …
Xylose-Derived Imidazole
Experimental
Matched Iupac: … (6R,7S,8S)-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …
DiaPep 277
DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).
Investigational
Matched Description: … DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460). …
Matched Categories: … Heat-Shock Proteins …
Matched Categories: … Heat-Shock Proteins …
Trapidil
Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
Experimental
Matched Iupac: … N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine …
Matched Description: … Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and …
Matched Description: … Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and …
Presatovir
Presatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections.
Investigational
Matched Iupac: … N-{2-[(2S)-2-{5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl}piperidine-1-carbonyl …
Patidegib
Patidegib has been investigated for the treatment of Conventional Chondrosarcoma.
Investigational
Matched Iupac: … ,6a,6b,7,7',7'a,8,10,12,12a,12b-icosahydro-1H,3'H-spiro[azuleno[2,1-a]naphthalene-9,2'-furo[3,2-b]pyridine ... N-[(3R,3'R,3'aS,4aR,6'S,6aR,6bS,7'aR,9S,12aS,12bS)-3',6',11,12b-tetramethyl-2,3,3'a,4,4',4a,5,5',6,6' …
DAR-0100A
DAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder).
Investigational
Matched Iupac: … (6aR,12bS)-5H,6H,6aH,7H,8H,12bH-benzo[a]phenanthridine-10,11-diol …
Matched Description: … DAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for …
Matched Description: … DAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for …
P-Cresol
Experimental
6-amino-1-methyl-7H-purin-1-ium
Experimental
3,4-Xylenol
Experimental
Displaying drugs 4326 - 4350 of 11286 in total