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Displaying drugs 4326 - 4350 of 11300 in total
Experimental
Experimental
Experimental
Experimental
Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Description: … Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 ... times greater than the HMG-CoA substrate itself. ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Experimental
Matched Iupac: … 4-{[6-(2,6-dichlorobenzoyl)imidazo[1,2-a]pyridin-2-yl]amino}benzene-1-sulfonamide …
Experimental
Matched Iupac: … (6R,7S,8S)-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Experimental
Matched Description: … It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. ... The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily …
Experimental
Experimental
mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Matched Description: … carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). ... consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA
Experimental
Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
Experimental
Matched Iupac: … N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine …
Matched Description: … Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and …
Experimental
Experimental
Presatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections.
Investigational
Matched Iupac: … N-{2-[(2S)-2-{5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl}piperidine-1-carbonyl …
Patidegib has been investigated for the treatment of Conventional Chondrosarcoma.
Investigational
Matched Iupac: … ,6a,6b,7,7',7'a,8,10,12,12a,12b-icosahydro-1H,3'H-spiro[azuleno[2,1-a]naphthalene-9,2'-furo[3,2-b]pyridine ... N-[(3R,3'R,3'aS,4aR,6'S,6aR,6bS,7'aR,9S,12aS,12bS)-3',6',11,12b-tetramethyl-2,3,3'a,4,4',4a,5,5',6,6' …
DAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder).
Investigational
Matched Iupac: … (6aR,12bS)-5H,6H,6aH,7H,8H,12bH-benzo[a]phenanthridine-10,11-diol …
Matched Description: … DAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for …
Investigational
Experimental
Experimental
Experimental
Displaying drugs 4326 - 4350 of 11300 in total