Displaying drugs 101 - 125 of 15280 in total
Acrivastine
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia.
Acrivastine is...
Approved
Matched Synonyms: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D …
Matched Categories: … Antihistamines for Systemic Use …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D …
Matched Categories: … Antihistamines for Systemic Use …
Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B Virus B/massachusetts/2/2012 Nymc Bx-51b Antigen (Formaldehyde Inactivated) …
Matched Name: … Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Name: … Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Pindolol
Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Synonyms: … 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol ... 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol ... 4-(2-hydroxy-3-isopropylaminopropoxy)-indole …
Matched Iupac: … 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. ... [A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348] ... [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s. …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Iupac: … 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. ... [A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348] ... [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s. …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Carboxin
A systemic agricultural fungicide and seed treatment agent.
Approved
Experimental
Matched Synonyms: … 5,6-Dihydro-2-methyl-1,4-oxathiin-3-carboxanilide ... 5,6-Dihydro-2-methyl-3-carboxanilido-1,4-oxathiin ... 5,6-Dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide …
Matched Iupac: … 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide …
Matched Description: … A systemic agricultural fungicide and seed treatment agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide …
Matched Description: … A systemic agricultural fungicide and seed treatment agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Trazodone
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Synonyms: … 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one …
Matched Iupac: … 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one …
Matched Description: … [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as ... [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms ... histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a …
Matched Salts cas: … 25332-39-2 …
Matched Categories: … Antidepressive Agents Indicated for Depression …
Matched Products: … TRAMADOL CLORHIDRATO 100 MG / 2 ML INYECTABLE …
Matched Iupac: … 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one …
Matched Description: … [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as ... [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms ... histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a …
Matched Salts cas: … 25332-39-2 …
Matched Categories: … Antidepressive Agents Indicated for Depression …
Matched Products: … TRAMADOL CLORHIDRATO 100 MG / 2 ML INYECTABLE …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 ... -methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... combination with other antivirals for all six genotypes of Hepatitis C [L852]. ... In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases …
Matched Mixtures name: … MYHEP ALL …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Antivirals for treatment of HCV infections …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... combination with other antivirals for all six genotypes of Hepatitis C [L852]. ... In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases …
Matched Mixtures name: … MYHEP ALL …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Antivirals for treatment of HCV infections …
Influenza A virus A/Kansas/14/2017 (H3N2) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Kansas/14/2017 (H3N2) live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Mixtures name: … INFLUVIRUS F …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Mixtures name: … INFLUVIRUS F …
Corifollitropin alfa
Corifollitropin alfa, also known as Elonva is used in women undergoing fertility treatment to stimulate the development of more than one mature egg (oocyte) at a time in the ovaries. This drug used together with a gonadotropin-releasing hormone (GnRH) antagonist, a type of medicine also used in fertility treatments. Elonva...
Approved
Investigational
Matched Description: … FDA for its New Drug Application for this drug. ... the development of more than one mature egg (oocyte) at a time in the ovaries. ... In July 2014, Merck announced the receipt of a Complete Response Letter (CRL) from the U.S. …
Matched Products: … GONAL-F ® 300 UI (22 MCG)/0.5 ML INYECTOR (FOLITROPINA ALFA (R-HFSH)) ... GONAL -F ® INYECTOR 450 UI (33MCG)/0.75ML. ... GONAL-F ® INYECTOR 900 UI (66 MCG)/1.5 ML …
Matched Products: … GONAL-F ® 300 UI (22 MCG)/0.5 ML INYECTOR (FOLITROPINA ALFA (R-HFSH)) ... GONAL -F ® INYECTOR 450 UI (33MCG)/0.75ML. ... GONAL-F ® INYECTOR 900 UI (66 MCG)/1.5 ML …
Alclofenac
Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … 3-Chloro-4-(2-propenyloxy)benzeneacetic acid ... (4-Allyloxy-3-chlorphenyl)essigsäure ... [4-(allyloxy)-3-chlorophenyl]acetic acid …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid …
Matched Description: … Alclofenac is a non-steroidal anti-inflammatory drug. ... It was withdrawn from the market in the United Kingdom in 1979. …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid …
Matched Description: … Alclofenac is a non-steroidal anti-inflammatory drug. ... It was withdrawn from the market in the United Kingdom in 1979. …
Matched Categories: … Non COX-2 selective NSAIDS …
Solriamfetol
Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with narcolepsy or obstructive sleep apnea[FDA Label]. Solriamfetol was given FDA approval in 2019[FDA Label].
Approved
Matched Synonyms: … (2R)-2-amino-3-phenylpropyl carbamate …
Matched Iupac: … (2R)-2-amino-3-phenylpropyl carbamate …
Matched Description: … Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine ... Solriamfetol was given FDA approval in 2019[FDA Label]. ... and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Iupac: … (2R)-2-amino-3-phenylpropyl carbamate …
Matched Description: … Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine ... Solriamfetol was given FDA approval in 2019[FDA Label]. ... and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Enprofylline
Enprofylline is a derivative of theophylline which shares bronchodilator properties. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable blood levels.
Approved
Experimental
Matched Synonyms: … 3-n-propylxanthine ... 3-propylxanthine ... 3-Propyl-3,7-dihydro-purine-2,6-dione …
Matched Iupac: … 3-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable ... blood levels. ... Enprofylline is a derivative of theophylline which shares bronchodilator properties. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable ... blood levels. ... Enprofylline is a derivative of theophylline which shares bronchodilator properties. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ethotoin
Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread...
Approved
Matched Synonyms: … (±)-3-ethyl-5-phenylhydantoin ... 3-ethyl-5-phenylhydantoin ... 3-ethyl-5-phenyl-2,4-imidazolidinedione …
Matched Iupac: … 3-ethyl-5-phenylimidazolidine-2,4-dione …
Matched Description: … Ethotoin is a hydantoin derivative and anticonvulsant. …
Matched Iupac: … 3-ethyl-5-phenylimidazolidine-2,4-dione …
Matched Description: … Ethotoin is a hydantoin derivative and anticonvulsant. …
Ceforanide
Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to...
Approved
Matched Synonyms: … (6R,7R)-7-[[2-[2-(aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl] ... 7β-[2-(aminomethyl)phenyl]acetamido-3-{[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl-3,4-didehydrocepham ... -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl ... }methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It has a longer elimination half-life than any currently available cephalosporin. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Iupac: … (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl ... }methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It has a longer elimination half-life than any currently available cephalosporin. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Milrinone
Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Synonyms: … 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile …
Matched Iupac: … 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile …
Matched Description: … [A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function ... Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. ... [A228323] Milrinone is a second-generation bipyridine phosphodiesterase (PDE) inhibitor created through …
Matched Salts cas: … 100286-97-3 …
Matched Mixtures name: … Milrinone Lactate in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Phosphodiesterase 3 Inhibitors …
Matched Products: … Milrinone Lactate in Dextrose ... MILRINONE-BAXTER CONCENTRATED SOLUTION FOR INJECTION 10MG/10ML …
Matched Iupac: … 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile …
Matched Description: … [A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function ... Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. ... [A228323] Milrinone is a second-generation bipyridine phosphodiesterase (PDE) inhibitor created through …
Matched Salts cas: … 100286-97-3 …
Matched Mixtures name: … Milrinone Lactate in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Phosphodiesterase 3 Inhibitors …
Matched Products: … Milrinone Lactate in Dextrose ... MILRINONE-BAXTER CONCENTRATED SOLUTION FOR INJECTION 10MG/10ML …
Fenoprofen
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Synonyms: … 2-(3-phenoxyphenyl)propionic acid ... (±)-2-(3-phenoxyphenyl)propionic acid ... DL-2-(3-phenoxyphenyl)propionic acid …
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) hemagglutinin antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) hemagglutinin antigen (UV, formaldehyde inactivated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Dactinomycin
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … N,N'-((2-AMINO-4,6-DIMETHYL-3-OXO-3H-PHENOXAZINE-1,9-DIYL)-BIS(CARBONYLIMINO(2-HYDROXYPROPYLIDENE)CARBONYLIMINOISOBUTYLIDENECARBONYL ... -PENTAOXO-1H-PYRROLO(2,1-I)(1,4,7,10,13)OXATETRAAZACYCLOHEXADECIN-10-YL)-4,6-DIMETHYL-3-OXO- ... (2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide …
Matched Iupac: … -1H-pyrrolo[2,1-i]1-oxa-4,7,10,13-tetraazacyclohexadecan-10-yl]-2-amino-4,6-dimethyl-3-oxo-3H-phenoxazine ... N1,N9-bis[(6S,9R,10S,13R,18aS)-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-bis(propan-2-yl)-hexadecahydro …
Matched Description: … A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces ... As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … DACTINOMYCIN FOR INJECTION 0.5 mg/vial …
Matched Iupac: … -1H-pyrrolo[2,1-i]1-oxa-4,7,10,13-tetraazacyclohexadecan-10-yl]-2-amino-4,6-dimethyl-3-oxo-3H-phenoxazine ... N1,N9-bis[(6S,9R,10S,13R,18aS)-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-bis(propan-2-yl)-hexadecahydro …
Matched Description: … A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces ... As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … DACTINOMYCIN FOR INJECTION 0.5 mg/vial …
Minoxidil
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Synonyms: … 2,4-Diamino-6-piperidinopyrimidine 3-oxide ... 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide …
Matched Description: … and produces a fall in blood pressure. ... A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance …
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Products: … REGRO LOTION 3% ... MINOXIDIL LOTION 3% w/v ... SW Minoxidil Lotion 3% w/v …
Matched Description: … and produces a fall in blood pressure. ... A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance …
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Products: … REGRO LOTION 3% ... MINOXIDIL LOTION 3% w/v ... SW Minoxidil Lotion 3% w/v …
Axitinib
Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Synonyms: … N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide …
Matched Iupac: … N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide …
Matched Description: … endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). ... Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular ... [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Products: … Axitinib STADA 3 mg Filmtabletten ... Axitinib Sandoz 3 mg – Filmtabletten ... INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET …
Matched Iupac: … N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide …
Matched Description: … endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). ... Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular ... [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Products: … Axitinib STADA 3 mg Filmtabletten ... Axitinib Sandoz 3 mg – Filmtabletten ... INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET …
Ethynodiol diacetate
A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Iupac: … -7-(acetyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually ... being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Description: … A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually ... being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Scorpion (centruroides) immune Fab2 antivenin (equine)
Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of C. noxius, C. l. limpidus, C. l. tecomanus, and C. s. suffusus. It is intravenously administered patients with clinical signs of scorpion envenomation so...
Approved
Matched Synonyms: … Centruroides (scorpion) Immune F(ab')2 (equine) ... Centruroides (scorpion) immune F(ab')2 (equine) injection ... Centruroides (scorpion) immune F(ab)2 intravenous (equine) …
Matched Description: … Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 ... Envenomation by a scorpion sting can result in serious cardiovascular effects [A32483]. ... *, *C. l. tecomanus*, and *C. s. suffusus*. …
Matched Description: … Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 ... Envenomation by a scorpion sting can result in serious cardiovascular effects [A32483]. ... *, *C. l. tecomanus*, and *C. s. suffusus*. …
Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic ... Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, …
Matched Categories: … Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … GRANEODIN F ... STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON ... Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic ... Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, …
Matched Categories: … Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … GRANEODIN F ... STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON ... Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …
Paromomycin
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Synonyms: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside ... Neomycin E ... Monomycin A …
Matched Iupac: … -6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl ... (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino ... ]oxy}-2-(hydroxymethyl)oxane-3,4-diol …
Matched Iupac: … -6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl ... (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino ... ]oxy}-2-(hydroxymethyl)oxane-3,4-diol …
Domperidone
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Synonyms: … 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone ... 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2 ... 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2 …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 ... -benzodiazol-2-one …
Matched Description: … A specific blocker of dopamine receptors. ... It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Functional Gastrointestinal Disorders …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 ... -benzodiazol-2-one …
Matched Description: … A specific blocker of dopamine receptors. ... It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Functional Gastrointestinal Disorders …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … -GLUTAMYL-L-TYROSYL-L-PROLYL-(2S)-2-CYCLOHEXYLGLYCYL-N6-(3 ... .-(2-(((4S)-4-CARBOXY-1-OXO-4-(1-OXOHEXADECYL)BUTYL)AMINO)ETHYL)-.OMEGA. ... -ASPARTYL-3-METHYL-L-VALYL-L-TYROSYL-3-(1H-PYRROLO(2,3-B)PYRIDIN-3-YL)-L-ALANYL-L-.ALPHA. …
Matched Iupac: … -benzyl-8-(3-carbamimidamidopropyl)-5-(2-carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan- ... 3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy-4 ... ]-3-(4-hydroxyphenyl)propanamido]-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]- ... 2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido ... (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11 …
Matched Description: … involved in the innate immune system to initiate inflammatory responses. ... It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein ... Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Matched Iupac: … -benzyl-8-(3-carbamimidamidopropyl)-5-(2-carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan- ... 3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy-4 ... ]-3-(4-hydroxyphenyl)propanamido]-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]- ... 2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido ... (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11 …
Matched Description: … involved in the innate immune system to initiate inflammatory responses. ... It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein ... Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Displaying drugs 101 - 125 of 15280 in total