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Displaying drugs 501 - 525 of 11565 in total
Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Iupac: … 9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … In a June 16 2020 press release highlighting early results of a clinical trial, Randomized Evaluation ... Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the ... [L10701] Recently, dexamethasone has been a drug of interest in the treatment of COVID-19. …
A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Description: … A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium …
Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions . Infliximab is produced by a recombinant cell line cultured by continuous perfusion. Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine involved in...
Approved
Matched Description: … Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody ... Inflectra, a first biosimilar drug product, was approved in 2016. ... Infliximab is produced by a recombinant cell line cultured by continuous perfusion. …
Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Description: … Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused …
Arexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with the accompanying vial of AS01E adjuvant as the adjuvant...
Approved
A long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Approved
Investigational
Matched Description: … A long-acting beta-2-adrenergic receptor agonist. ... It is a potent bronchodilator that may be administered orally or by aerosol inhalation. …
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While...
Approved
Investigational
Matched Description: … Amphotericin B shows a high order of in vitro activity against many species of fungi. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
Approved
Matched Description: … Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial …
A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
Approved
Investigational
Vet approved
Matched Description: … It is used as a bronchodilator in asthma. ... A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. …
Medical air is supplied by a special air compressor to patient care areas using clean outside air.
Approved
Vet approved
Matched Description: … Medical air is supplied by a special air compressor to patient care areas using clean outside air. …
Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide ... It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Approved
Investigational
Amorolfine or amorolfin, is a morpholine antifungal drug that inhibits the fungal enzymes D14 reductase and D7-D8 isomerase. This inhibition affects fungal sterol synthesis pathways, depleting ergosterol and causing ignosterol to accumulate in the fungal cytoplasmic cell membranes. Amorolfine is marketed as Curanail, Loceryl, Locetar, and Odenil. It is available...
Approved
Investigational
Matched Description: … It is a topical solution for the treatment of toenail infections. ... Amorolfine or amorolfin, is a morpholine antifungal drug that inhibits the fungal enzymes D14 reductase ... It is available in the form of a 5% amorolfine nail lacquer used to treat onychomycosis (fungal infection …
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Approved
Withdrawn
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Description: … A short-acting opioid anesthetic and analgesic derivative of fentanyl. …
Urea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as Pranactin-Citric) for the detection of Helicobacter pylori infections. H pylori is a common stomach bacteria that has been...
Approved
Matched Description: … H pylori is a common stomach bacteria that has been linked to a variety of upper gastrointestinal disorders ... Urea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. ... It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed …
Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Because integrase is necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and thereby blocks the formation of the...
Approved
Matched Description: … Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI ... Although available as a single dose tablet, elvitegravir must be used in combination with an HIV protease …
Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that causes severe disability in pediatric patients.[L43642,L43672] Patients with AADC have mutations in the dopa decarboxylase (DDC) gene...
Approved
Investigational
Matched Description: … Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses ... human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and …
Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts cell division, differentiation, and secretion. Mutations in this gene,...
Approved
Investigational
Matched Description: … Encorafenib, also known as _BRAFTOVI_, is a kinase inhibitor. ... Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in ... [L12216] This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts …
Albumin aggregated is an ingredient in the DRAXIMAGE MAA kit for the preparation of technetium tc99m albumin aggregated injection. This imaging agent is used to assess lung perfusion and for the evaluation of peritoneovenous (LeVeen) shunt patency.
Approved
Hydrocortamate is a synthetic glucocorticoid used for its anti-inflammatory or immunosuppressive properties to treat inflammation due to corticosteroid-responsive dermatoses. Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects.
Approved
Matched Iupac: … 1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Hydrocortamate is a synthetic glucocorticoid used for its anti-inflammatory or immunosuppressive properties ... Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol ... receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects …
Approved
Matched Iupac: … fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched International brands: … Clenil-A
Matched Iupac: … 2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone …
Displaying drugs 501 - 525 of 11565 in total