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Displaying drugs 351 - 375 of 425 in total
Ipriflavone
Experimental
Matched Categories: … Bone Remodeling ... Drugs for Treatment of Bone Diseases ... Drugs Affecting Bone Structure and Mineralization …
Menatetrenone
Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma.
Investigational
Matched Categories: … Drugs for Treatment of Bone Diseases ... Drugs Affecting Bone Structure and Mineralization …
DOTMP HO-166
DOTMP HO-166 is used in skeletal targeted radiotherapy (STR). SRT is designed to be used in combination with high-dose chemotherapy producing a direct therapeutic effect on the tumor sites in the bone plus a general bone-marrow effect to destroy myeloma cells in the bone marrow. It is an experimental therapy...
Investigational
Matched Description: … plus a general bone-marrow effect to destroy myeloma cells in the bone marrow. ... combination with high-dose chemotherapy producing a direct therapeutic effect on the tumor sites in the bone …
Procalcitonin
Procalcitonin is under investigation in clinical trial NCT03440060 (Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD).
Investigational
Matched Categories: … Bone Density Conservation Agents …
Incadronic acid
Incadronate, or YM-175, is a nitrogen containing bisphosphonate. Along with being investigated to treat hypercalcemia of malignancy, it has also been investigated in the treatment of myeloma, leukemia, and other cancers.[A14426,A14431,A14427,A202769]
Incadronic acid was first described in the literature in 1991.
Experimental
Matched Categories: … Bone Density Conservation Agents …
Odanacatib
Odanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment for osteoporosis . The drug made it to phase III trials before abandoned due to increased stroke.
Investigational
Methopterin
Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction.
Investigational
Matched Description: … Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction. …
Strontium malonate
Strontium malonate is being developed as a novel orally available pharmaceutical for the treatment and prevention of osteoporosis. It is being developed by Osteologix Inc.
Investigational
AMGN-0007
Recombinant osteoprotegerin (AMGN-0007) is a recombinant OPG construct developed as a potential therapeutic agent in the treatment of bone disease.
Investigational
Matched Description: … 0007) is a recombinant OPG construct developed as a potential therapeutic agent in the treatment of bone …
Eldecalcitol
Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.
Investigational
Matched Description: … Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol ... Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic …
Matched Categories: … Bone Density Conservation Agents …
Matched Categories: … Bone Density Conservation Agents …
Calcitonin porcine
Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in...
Experimental
Matched Description: … It inhibits bone resorption and lowers both serum and urinary calcium concentrations. …
Matched Categories: … Bone Density Conservation Agents …
Matched Categories: … Bone Density Conservation Agents …
Gallium maltolate
Gallium maltolate is Titan’s novel oral agent in development for the potential treatment of chronic bacterial infections, bone disease and cancer.
Investigational
Matched Description: … Titan’s novel oral agent in development for the potential treatment of chronic bacterial infections, bone …
inBreath airway transplant system
inBreath airway transplant system composes of a scaffold seeded with autologous bone marrow cells and incubated in the bioreactor for two days prior to implant.
Investigational
Matched Description: … inBreath airway transplant system composes of a scaffold seeded with autologous bone marrow cells and …
Ixmyelocel-T
Ixmyelocel-T is an expanded, autologous multicellular therapy cultured from bone-marrow mononuclear cells. Developed by Vericel Corporation, it is being investigated for cardiomyopathy.
Investigational
Matched Description: … Ixmyelocel-T is an expanded, autologous multicellular therapy cultured from bone-marrow mononuclear cells …
Repifermin
Investigational
TP-508
TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified as the fibroblast high-affinity receptor binding domain.
Investigational
MIV-701
MIV-701 is a selective, potent inhibitor of the protease Cathepsin K. It is developed for the treatment of osteoporosis.
Investigational
Afabicin
Afabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus).
Investigational
Matched Description: … Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone …
Calcium
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
Matched Description: … Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. ... Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Drugs Affecting Bone Structure and Mineralization …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Drugs Affecting Bone Structure and Mineralization …
Radium Ra-223
Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC).
Investigational
Matched Description: … (Ph 2 Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC …
Relacatib
Investigational
Ridaforolimus
Investigational
24,25-Dihydroxycholecalciferol
Investigational
Matched Categories: … Bone Density Conservation Agents …
Galiximab
Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug.
Investigational
Displaying drugs 351 - 375 of 425 in total