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Displaying drugs 26 - 50 of 2297 in total
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … ), and docosahexaenoic acid (DHA) [L1500, L1510]. ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Approved
Investigational
Matched Synonyms: … Acetic acid, zinc salt ... Zinc acetato ... Zinc diacetate …
Matched Name: … Zinc acetate …
Matched Iupac: … zinc(2+) diacetate …
Matched Mixtures name: … Diphenhydramine HCI and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate …
Matched Salts name: … Zinc acetate dihydrate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... zinc acetate …
Matched Products: … Halls Zinc Defense …
CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Synonyms: … immunity- and matrix-regulatory cells ... Immunity-and-matrix-regulatory cells …
Matched Description: … anti-fibrotic functions, and being stronger in potential treatment of lung injury and fibrosis. ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
Investigational
Matched Synonyms: … Hypothiocyanite and lactoferrin …
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and
EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... ) at the HBG1 and HBG2 promoters ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Name: … Fenofibric acid
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid
Matched Description: … ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed ... , and mixed dyslipidemia. ... for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration …
Matched Categories: … Acids, Acyclic ... Fibric Acids ... Carboxylic Acids
Matched Products: … Fenofibric Acid ... Fenofibric acid ... ACIDO FENOFIBRICO 135 MG …
SP1049C is a novel anthracycline chemotherapeutic agent containing doxorubicin and two nonionic pluronic block copolymers. It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. Preliminary data, in its first clinically tested indication,...
Investigational
Matched Synonyms: … doxorubicin with pluronics F-127 and L-61 ... Doxorubicin HCl with pluronic L-61 and pluronic F-127 …
Matched Description: … Median survival is encouraging and correlates strongly with dose levels.[A260416] ... SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic …
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … Carglumic acid ... Acide carglumique ... Acidum carglumicum …
Matched Name: … Carglumic acid
Matched Iupac: … (2S)-2-(carbamoylamino)pentanedioic acid
Matched Description: … Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and
Matched Categories: … Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids
Matched Products: … Carglumic Acid ... Carglumic acid ... ACIDO CARGLUMICO WAYMADE …
PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).
Investigational
Matched Synonyms: … Human umbilical cord and placental blood plasma …
Matched Description: … PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental ... [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory …
Investigational
Matched Synonyms: … 72 amino acid proprietary recombinant protein antagonist for the CXCR1 and CXCR2 receptors of interleukin ... CXC chemokine receptor types 1 and 2 inhibitor RP72 …
VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C. As there already exists a polysaccharide-based vaccine against meningococcal disease originating from serogroups A,C,W135, and...
Investigational
Matched Synonyms: … Meningococcal polysaccharide vaccine groups B and C …
Matched Description: … VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. ... The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide ... Y, this vaccine was created for use against serogroups B and C. …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. …
Matched Mixtures name: … Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Gastric Acid Lowering Agents …
Matched Products: … Up and Up Acid Reducer ... Acid Reducer ... Equaline Acid Reducer …
Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff shampoo, but is no longer available. It is currently used as a pesticide, and not used in any FDA approved drug products. Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum antitumor activity, which...
Approved
Matched Synonyms: … Pyrithione disulfide ... Pyrithione disulphide …
Matched Description: … [A32825] Pyrithione derivatives, such as [DB06815] and sodium pyrithione, are widely used as cosmetic ... Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff ... [A32829] Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum …
Investigational
Matched Synonyms: … Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared and coated with anti-MHC …
Approved
Matched Mixtures name: … Sunset Pain Relief Heating Camphor and Amino Acids ... Menthol and Zinc Oxide ... Menthol and Zinc Oxide …
Matched Products: … Lactic Acid Free M Synergy for male ... Highpothecary Therapeutics CBD Zing ... SmartMouth Mouth Sore Zinc Activated Formula …
Experimental
Matched Synonyms: … p-salicylic acid ... p-Hydroxybenzoic acid
Matched Name: … 4-hydroxybenzoic acid
Matched Iupac: … 4-hydroxybenzoic acid
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Retinoic acid ... Retionic acid ... Acide retinoique …
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin ... activates nuclear receptors to regulate epithelial cell growth and differentiation. ... [A257689] Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging …
Matched Mixtures name: … Imiquimod 5% / Salicylic Acid 30% / Tretinoin 0.1% ... Clindamycin Phosphate and Tretinion ... OLIVIA QUIDO FIRM and FADE I …
Matched Categories: … Cell Stimulants and Proliferants ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Vitamin A Acid ... ACIDO RETINOICO ... Vitamin A Acid 0.1% Cream …
Approved
Investigational
Matched Synonyms: … Glycollic acid ... 2-Hydroxyacetic acid ... Hydroxyacetic acid
Matched Name: … Glycolic acid
Matched Iupac: … 2-hydroxyacetic acid
Matched Mixtures name: … Clear Cell Salicylic Clarifying Tonic ... CREMA CON ACIDO GLICOLICO AL 8% …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Glycolic Acid ... ACIDO GLICOLICO OVOCELL …
Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA 250IU powder and solvent for solution for injection …
Investigational
Matched Synonyms: … Recombinant antibody construct against human CD30 and CD16A …
Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Synonyms: … Chenic acid ... Chenocholic acid ... Acido chenodeoxicholico …
Matched Name: … Chenodeoxycholic acid
Matched Iupac: … 9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol ... in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. ... Chenodeoxycholic acid is a bile acid naturally found in the body. …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Cholic Acids
Matched Products: … Chenodeoxycholic Acid Leadiant ... ACIDO CHENODESOSSICOLICO LEADIANT …
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... effect and modulation of the microbial composition of the dental biofilm [A19581]. ... compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Sensodyne Sensitivity and Gum Clean and Fresh ... Gel-Kam Fruit and Berry ... H E B Restore and Defend …
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Displaying drugs 26 - 50 of 2297 in total