Displaying drugs 26 - 50 of 1651 in total
Efanesoctocog alfa
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl …
Matched Description: … Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the …
Matched Description: … Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the …
Respiratory syncytial virus vaccine, adjuvanted
Arexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with the accompanying vial of AS01E adjuvant as the adjuvant...
Approved
Matched Synonyms: … RECOMBINANT RESPIRATORY SYNCYTIAL VIRUS PRE-FUSION F PROTEIN ... RESPIRATORY SYNCYTIAL VIRUS PREFUSION F PROTEIN (RSVPREF3) …
Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine
The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19. It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with...
Approved
Matched Synonyms: … Recombinant SARS-CoV-2 spike (S)-protein virus-like particle …
Matched Description: … [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion …
Matched Description: … [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion …
Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup a. The vaccine contains N. meningitis serogroup a capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Investigational
Matched Synonyms: … Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains* N. meningitis* serogroup y capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Synonyms: … Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Somatrogon
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … CTP-SOMATROPIN FUSION PROTEIN ... -SUBUNIT) FUSION PROTEIN WITH SOMATOTROPIN (HUMAN) FUSION PROTEIN WITH 118-145-CHORIONIC GONADOTROPIN ... SOMATROPIN-CTP FUSION PROTEIN …
Matched Description: … [A241515,L39362] The glycosylation and the presence of CTPs in the protein sequence prolongs the half-life …
Matched Description: … [A241515,L39362] The glycosylation and the presence of CTPs in the protein sequence prolongs the half-life …
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains N. meningitis serogroup W-135 capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Synonyms: … Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Tagraxofusp
Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia coli.[A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018...
Approved
Investigational
Matched Synonyms: … Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor …
Matched Description: … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic …
Matched Description: … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic …
VidPrevtyn Beta
VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is
derived from Sf9 cells of the fall...
Approved
Investigational
Matched Synonyms: … SARS-CoV-2 prefusion Spike delta TM protein, recombinant (B.1.351 strain) …
Matched Description: … [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant …
Matched Description: … [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Matched Description: … Mecasermin rinfabate however, is already bound to recombinant DNA origin insulin-like growth factor binding protein …
Matched Description: … Mecasermin rinfabate however, is already bound to recombinant DNA origin insulin-like growth factor binding protein …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP ... IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP …
Matched Description: … Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed …
Matched Description: … Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … Wap four-disulfide core domain protein 4 …
Albumin human
Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood . It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately...
Approved
Matched Description: … Human serum albumin is the primary protein present in human blood plasma. ... Albumin represents approximately 50% of the total protein content in healthy humans [A40060]. ... Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain …
Matched Mixtures name: … Venomil Wasp Venom Protein (12mcg) ... Venomil Yellow Hornet Venom Protein (12mcg) ... Venomil Yellow Jacket Venom Protein (12mcg) …
Matched Categories: … Blood Substitutes and Plasma Protein Fractions …
Matched Products: … Plasma Protein Lösung 50 g/l Infusionslösung …
Matched Mixtures name: … Venomil Wasp Venom Protein (12mcg) ... Venomil Yellow Hornet Venom Protein (12mcg) ... Venomil Yellow Jacket Venom Protein (12mcg) …
Matched Categories: … Blood Substitutes and Plasma Protein Fractions …
Matched Products: … Plasma Protein Lösung 50 g/l Infusionslösung …
Coal tar
Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.
It has been...
Approved
Matched Products: … Herbal Castle Deep Cleansing Protein Tar Shampoo …
Human C1-esterase inhibitor
C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways.[L16586, L16606]
This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a...
Approved
Pozelimab
CD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US. The pathophysiology of this disease is mainly attributed to the deficiency of the CD55 protein, which is the main regulator of the complement...
Approved
Investigational
Matched Description: … CD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease ... [L47880] The pathophysiology of this disease is mainly attributed to the deficiency of the CD55 protein ... Pozelimab is a human, monoclonal immunoglobulin G4P antibody against the terminal complement protein …
Threonine
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Approved
Nutraceutical
Gadoxetic acid
Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Pembrolizumab
Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Categories: … PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors …
Phenelzine
Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Approved
Selumetinib
Activation of the Raf-MEK-ERK signalling pathway is known to be implemented in several types of malignancies; thus, mitogen-activated protein kinase kinase (MEK) inhibitors such as selumetinib are important tools that can target the problematic overactivity of this pathway. Results from clinical trials investigating earlier developed MEK inhibitors were underwhelming. However,...
Approved
Investigational
Matched Description: … signalling pathway is known to be implemented in several types of malignancies; thus, mitogen-activated protein …
Matched Categories: … Protein Kinase Inhibitors ... Mitogen-activated protein kinase (MEK) inhibitors ... Mitogen-Activated Protein Kinase Kinase 1 Inhibitors ... Mitogen-Activated Protein Kinase Kinase 2 Inhibitors …
Matched Categories: … Protein Kinase Inhibitors ... Mitogen-activated protein kinase (MEK) inhibitors ... Mitogen-Activated Protein Kinase Kinase 1 Inhibitors ... Mitogen-Activated Protein Kinase Kinase 2 Inhibitors …
Mosunetuzumab
Mosunetuzumab is a humanized anti-CD20/CD3 bispecific antibody. It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells. The standard of care for patients with B-cell lymphoma includes an anti-CD20 monoclonal antibody, such as...
Approved
Investigational
Medrogestone
Medrogestone (INN), also known as 6,17α-dimethyl-6-dehydroprogesterone, is a progestational agent derived from 17-methylprogesterone. It was conceived as an alternative for an orally effective contraceptive option. It was developed by Ayerst, approved in Canada in 1969 and its current status is cancelled post-marketing. It was never approved by the FDA.
Approved
Withdrawn
Displaying drugs 26 - 50 of 1651 in total