Displaying drugs 6776 - 6800 of 8028 in total
Feladilimab
Feladilimab is under investigation in clinical trial NCT04128696 (Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma).
Investigational
Matched Description: … Feladilimab is under investigation in clinical trial NCT04128696 (Study of GSK3359609 and Pembrolizumab …
RR001
RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …
Inetetamab
Inetetamab is a trastuzumab analog. It differs from trastuzumab by a two amino acid variation in its Fc domain (allotype variation), and possesses an exact F(ab’)2 of trastuzumab.
Investigational
Matched Description: … by a two amino acid variation in its Fc domain (allotype variation), and possesses an exact F(ab’)2 of …
ALMB-0166
ALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of acute spinal cord injury. It was granted FDA orphan designation in November 2018.
Investigational
Matched Description: … ALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of …
4-Hydroxytestosterone
4-Hydroxytestosterone is testosterone substituted with a hydroxy group on the fourth carbon atom. It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by the World Anti-Doping Agency.
Formestane (Lentaron) acts as a prohormone of 4-Hydroxytestosterone, as 4-Hydroxytestosterone is one of the many byproducts...
Experimental
Illicit
Matched Description: … of the many byproducts of formestane metabolism. ... Formestane (Lentaron) acts as a prohormone of 4-Hydroxytestosterone, as 4-Hydroxytestosterone is one …
Indopan
Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United...
Experimental
Illicit
Picolinic acid
PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. PCL-016 plays a key role in zinc transport. As a...
Investigational
Matched Description: … PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. ... is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of ... Acne vulgaris, herpes and other viral infections therefore pose potential therapeutic targets of PCL- …
Fenbendazole
Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides. Fenbendazole is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs,...
Vet approved
Matched Description: … It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms ... , the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides …
VB10.16
VB10.16 is a novel therapeutic antigen-presenting cell-targeting DNA vaccine developed to treat HPV16-positive cancers. It is composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type 16 (HPV16), a dimerization entity, and the part encoding a protein that specifically binds to antigen-presenting cells (APCs).
Investigational
Matched Description: … It is composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type …
SYNB1353
SYNB1353 is a strain of the probiotic bacteria Escherichia coli (E. coli) type Nissle and an engineered probiotic drug. Developed by Synlogic Operating Company, Inc., SYNB1353 is being investigated for the treatment of homocystinuria. It is designed to consume methionine in the gastrointestinal tract to prevent its absorption and conversion...
Investigational
Matched Description: … SYNB1353 is a strain of the probiotic bacteria _Escherichia coli_ (_E. coli_) type Nissle and an engineered ... A258833] Developed by Synlogic Operating Company, Inc., SYNB1353 is being investigated for the treatment of …
GS030-DP
GS030-DP is an optogenetic gene therapy being investigated for the treatment of retinitis pigmentosa. It targets retinal ganglion cells that encodes a light-sensitive channelrhodopsin, ChrimsonR-tdTomato (ChR-tdT), delivered by an AAV2.7m8 vector. It is a component of GS030, an investigational optogenetic treatment, in combination with a medical device GS030-MD.[A259816, L46701]
Investigational
Matched Description: … GS030-DP is an optogenetic gene therapy being investigated for the treatment of retinitis pigmentosa. ... It is a component of GS030, an investigational optogenetic treatment, in combination with a medical device …
Duvoglustat
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Investigational
Matched Description: … Derivatives of deoxynojirimycin may have anti-HIV activity. …
FP-1096
FP1096 reduced the painful symptoms of endometriosis in trial subjects with very minimal side effect.
Investigational
Matched Description: … FP1096 reduced the painful symptoms of endometriosis in trial subjects with very minimal side effect. …
Talaporfin
Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
Investigational
Matched Description: … Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia …
Pritelivir
Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
Investigational
Matched Description: … Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes. …
Riboprine
Ipa has been used in trials studying the treatment of Nausea and Surgical Site Infection.
Investigational
Matched Description: … Ipa has been used in trials studying the treatment of Nausea and Surgical Site Infection. …
AZD-4818
AZD4818 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease (COPD).
Investigational
Matched Description: … AZD4818 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease (COPD …
Ammonio methacrylate copolymer type A
Ammonio methacrylate copolymer type a has been used in trials studying the treatment of GERD.
Investigational
Matched Description: … Ammonio methacrylate copolymer type a has been used in trials studying the treatment of GERD. …
Vesnarinone
Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
Investigational
Matched Description: … Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi. …
Tricaprylin
Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
Investigational
Matched Description: … Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease …
Fosdagrocorat
Fosdagrocorat has been used in trials studying the treatment and basic science of Rheumatoid Arthritis.
Investigational
Matched Description: … Fosdagrocorat has been used in trials studying the treatment and basic science of Rheumatoid Arthritis …
TRV-120027
TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease.
Investigational
Matched Description: … TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease. …
Balapiravir
Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic.
Investigational
Matched Description: … Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic. …
Fezakinumab
Fezakinumab has been used in trials studying the treatment of Atopic Dermatitis and Rheumatoid Arthritis.
Investigational
Matched Description: … Fezakinumab has been used in trials studying the treatment of Atopic Dermatitis and Rheumatoid Arthritis …
Bitopertin
Bitopertin has been used in trials studying the treatment of Schizophrenia and Obsessive-Compulsive Disorder.
Investigational
Matched Description: … Bitopertin has been used in trials studying the treatment of Schizophrenia and Obsessive-Compulsive Disorder …
Displaying drugs 6776 - 6800 of 8028 in total