Displaying drugs 676 - 700 of 708 in total
Trastuzumab duocarmazine
Trastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).
Investigational
Matched Synonyms: … receptor tyrosineprotein kinase erbb-2, egfr2, her2, her-2, p185cerbb2, neu, cd340)), humanized monoclonal antibody …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Lintuzumab satetraxetan AC-225
Lintuzumab actinium Ac-225 is under investigation in clinical trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies).
Investigational
Matched Synonyms: … Actinium-225-labeled humanized anti-cd33 monoclonal antibody HUM195 …
Matched Description: … trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody …
Matched Description: … trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Description: … Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness ... of breath and the coughing up of blood. ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. …
Matched Categories: … cefepime and amikacin …
Matched Products: … VERDIX …
Matched Categories: … cefepime and amikacin …
Matched Products: … VERDIX …
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Creobic Gold Cream 1% w/w …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Creobic Gold Cream 1% w/w …
Sotigalimab
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … CD40 AGONISTIC MONOCLONAL ANTIBODY APX005M …
Matched Description: … Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Olinvacimab
Olinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Fully human monoclonal antibody targets vascular endothelial growth factor receptor 2 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Perenostobart
Perenostobart is an alpha-CD39 IgG4 monoclonal antibody.
Investigational
Matched Synonyms: … ectonucleoside triphosphate diphosphohydrolase 1, NTPDase-1, ATPDase, SPG64, CD39)], Homo sapiens monoclonal antibody …
Matched Description: … Perenostobart is an alpha-CD39 IgG4 monoclonal antibody. …
Matched Description: … Perenostobart is an alpha-CD39 IgG4 monoclonal antibody. …
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … MONOCLONAL ANTIBODY AK002 ... Recombinant humanized, non-fucosylated IgG1 anti-Siglec-8 monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pucotenlimab
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Humanized pd-1 blocking antibody hx-008 …
Matched Description: … Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. …
Matched Description: … Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. …
Anti-SARS-CoV-2 immunoglobulin
Hyperimmune immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and develop neutralizing antibodies. Anti-coronavirus immunoglobulin is derived from COVID-19 convalescent plasma(https://go.drugbank.com/drugs/DB15692) but contains more SARS-CoV-2 neutralizing antibodies than found in convalescent plasma (https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and concentrated.[L27521, L27526]
Investigational
Matched Synonyms: … SARS-CoV-2 antibody-based IVIG …
Matched Description: … immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and ... [convalescent plasma](https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and ... [convalescent plasma](https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ripertamab
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Synonyms: … -(homo sapiens ms4a1 (membrane-spanning 4-domains subfamily a member 1, cd20)), chimeric monoclonal antibody …
Matched Description: … Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated ... Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and …
Matched Description: … Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated ... Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and …
Elranatamab
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … ANTI-CD3/ANTI-BCMA BISPECIFIC MONOCLONAL ANTIBODY PF-06863135 ... B-CELL MATURATION ANTIGEN (BCMA) CLUSTER OF DIFFERENTIATION 3 (CD3) BISPECIFIC MONOCLONAL ANTIBODY (MAB …
Matched Description: … ), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light ... It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs ... The resulting 4-chain bispecific antibody is covalently linked via five inter-chain disulfide bonds. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … ), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light ... It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs ... The resulting 4-chain bispecific antibody is covalently linked via five inter-chain disulfide bonds. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Description: … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation ... It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. …
Matched Products: … VERISAN …
Matched Products: … VERISAN …
Carotuximab
Investigational
Matched Synonyms: … Chimeric anti-CD105 antibody ... IMMUNOGLOBULIN G1-KAPPA, ANTI-(HUMAN ENDOGLIN (CD105 ANTIGEN)) HUMAN MOUSE CHIMERIC MONOCLONAL ANTIBODY …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ozekibart
Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Investigational
Matched Synonyms: … Tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5 …
Matched Description: … Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death …
Matched Description: … Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death …
Chlorpheniramine
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. ... One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and …
Matched Mixtures name: … Contac Gold ... Cold Max Day and Night ... Coricidin HBP Day and Night …
Matched Products: … Chlor-tripolon Night Time Allergy Relief …
Matched Mixtures name: … Contac Gold ... Cold Max Day and Night ... Coricidin HBP Day and Night …
Matched Products: … Chlor-tripolon Night Time Allergy Relief …
Miromavimab
Investigational
Matched Synonyms: … strain era (evelyn-rockitniki-abelseth) glycoprotein ectodomain epitope g-ii), mus musculus monoclonal antibody …
Diclofenac
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever …
Pabinafusp alfa
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused …
Casdozokitug
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[IL27 (interleukin 27,IL27p28, IL27A)], Homo sapiens monoclonal antibody …
Dazukibart
Investigational
Matched Synonyms: … Recombinant humanized monoclonal antibody (immunoglobulin gamma-1 with kappa light chains, IgG1kappa) …
Mezagitamab
Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and Efficacy of TAK-079 in Participants With Persistent/chronic Primary Immune Thrombocytopenia).
Investigational
Matched Synonyms: … Anti-Cd38 monoclonal antibody TAK-079 …
Matched Description: … Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and …
Matched Description: … Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and …
Edobacomab
Investigational
Matched Synonyms: … Monoclonal antiendotoxin antibody XMMEn-0e5 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Porgaviximab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(EBOLAVIRUS GLYCOPROTEIN) CHIMERIC HOMO SAPIENS-MUS MUSCULUS MONOCLONAL ANTIBODY …
Cantuzumab mertansine
Investigational
Matched Synonyms: … Maytansine, n2-deacetyl-n2-(3-mercapto-1-oxopropyl)-, conjugated humanized c242 monoclonal antibody ... N2'-deacetyl-n2'-(3-mercapto-1-oxopropyl)-maytansine -conjugated humanized c242 monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Displaying drugs 676 - 700 of 708 in total