Displaying drugs 76 - 88 of 88 in total
Ceftaroline fosamil
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria:
Acute bacterial skin and skin structure infections.
Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin ... -1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate …
Matched Iupac: … ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium ... 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido …
Matched Description: … Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections …
Matched Salts cas: … 400827-46-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium ... 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido …
Matched Description: … Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections …
Matched Salts cas: … 400827-46-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ceftizoxime
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2- ... syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 ... ]oct-2-ene-2-carboxylic acid …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. …
Matched Salts cas: … 68401-82-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … CEFIZOX 1 GR FLAKON, 1 ADET ... CEFİZOX 1 G IM ENJEKSİYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET ... CEFİZOX 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 ... ]oct-2-ene-2-carboxylic acid …
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. …
Matched Salts cas: … 68401-82-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … CEFIZOX 1 GR FLAKON, 1 ADET ... CEFİZOX 1 G IM ENJEKSİYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET ... CEFİZOX 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET …
Delafloxacin
Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections, and Community Acquired Pneumonia, among others. It was approved in June 2017 under the trade name Baxdela for use in the treatment of...
Approved
Investigational
Matched Iupac: … 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Matched Description: … Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and ... It was approved in June 2017 under the trade name Baxdela for use in the treatment of acute bacterial …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and ... It was approved in June 2017 under the trade name Baxdela for use in the treatment of acute bacterial …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Gemifloxacin
Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are...
Approved
Investigational
Matched Iupac: … 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8 ... -naphthyridine-3-carboxylic acid …
Matched Description: … Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ONFACT 320 MG FİLM TABLET, 5 ADET ... FACTIVE 320 MG FİLM TABLET, 5 ADET ... GEMİLOKS 320 MG FİLM KAPLI TABLET, 5 ADET …
Matched Description: … Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ONFACT 320 MG FİLM TABLET, 5 ADET ... FACTIVE 320 MG FİLM TABLET, 5 ADET ... GEMİLOKS 320 MG FİLM KAPLI TABLET, 5 ADET …
Enoxacin
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Synonyms: … 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid ... 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … REKSOTİN 400 MG FİLM TABLET, 14 TABLET …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … REKSOTİN 400 MG FİLM TABLET, 14 TABLET …
Gatifloxacin
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. …
Matched Salts cas: … 404858-36-2 ... 180200-66-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. …
Matched Salts cas: … 404858-36-2 ... 180200-66-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Eravacycline
Eravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacteria. This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic...
Approved
Investigational
Matched Iupac: … (4S,4aS,5aR,12aS)-4-(dimethylamino)-7-fluoro-3,10,12,12a-tetrahydroxy-1,11-dioxo-9-[2-(pyrrolidin-1-yl ... )acetamido]-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide …
Matched Description: … It was first approved by the FDA on August 27, 2018 [L4540]. ... Eravacycline, known as _Xerava_ by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Description: … It was first approved by the FDA on August 27, 2018 [L4540]. ... Eravacycline, known as _Xerava_ by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic …
Matched Categories: … Monoamine Oxidase A Substrates …
Bacampicillin
Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Synonyms: … 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia ... -1-azabicyclo[3.2.0]heptane-2-carboxylate ... 1'-ethoxycarbonyloxyethyl-(6-D-α-aminophenylacetamido)penicillanate …
Matched Iupac: … 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia- ... 1-azabicyclo[3.2.0]heptane-2-carboxylate …
Matched Description: … of the biosynthesis of cell wall mucopeptides. ... Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. ... It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia- ... 1-azabicyclo[3.2.0]heptane-2-carboxylate …
Matched Description: … of the biosynthesis of cell wall mucopeptides. ... Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. ... It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Dirithromycin
Dirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.
Experimental
Matched Synonyms: … (9S)-9-deoxo-11-deoxy-9,11-(imino((1R)-2-(2-methoxyethoxy)ethylidene)oxy)erythromycin …
Matched Iupac: … -2-yl]oxy}-3-ethyl-2,10-dihydroxy-7-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-15 ... -[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one ... (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-9-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan …
Matched Description: … Dirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial …
Matched Products: … DYNABAC 250 MG ENTERİK KAPLI TABLET, 14 ADET …
Matched Iupac: … -2-yl]oxy}-3-ethyl-2,10-dihydroxy-7-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-15 ... -[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one ... (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-9-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan …
Matched Description: … Dirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial …
Matched Products: … DYNABAC 250 MG ENTERİK KAPLI TABLET, 14 ADET …
Rifalazil
Rifalazil is a derivative of the antibiotic rifamycin. It is being investigated by ActivBiotics for the treatment of various bacterial infections.
Investigational
Matched Synonyms: … 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin …
Matched Iupac: … (2-methylpropyl)piperazin-1-yl]-6,23,37-trioxo-8,27,38-trioxa-24,34-diazahexacyclo[23.11.1.1^{4,7}.0^ ... ,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30-[4- …
Matched Description: … Rifalazil is a derivative of the antibiotic rifamycin. …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Iupac: … (2-methylpropyl)piperazin-1-yl]-6,23,37-trioxo-8,27,38-trioxa-24,34-diazahexacyclo[23.11.1.1^{4,7}.0^ ... ,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30-[4- …
Matched Description: … Rifalazil is a derivative of the antibiotic rifamycin. …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Iclaprim
Investigational
Matched Iupac: … 5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine …
Matched Salts cas: … 474793-41-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 474793-41-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
BACTEK-R
MV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that are involved in upper and lower respiratory infections. These include streptococcus pneumoniae and staphylococcus aureus. Though studies have shown that it reduces the rate of infections in recurrent respiratory tract infections (RRTIs), the complete mechanisms are not fully...
Investigational
Matched Description: … These include streptococcus pneumoniae and staphylococcus aureus. ... MV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that …
Temafloxacin
Temafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class. It was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three deaths.
Withdrawn
Matched Iupac: … 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 76 - 88 of 88 in total