Displaying drugs 1026 - 1050 of 1108 in total
Rilzabrutinib
Rilzabrutinib is an oral, reversible covalent inhibitor of Bruton's tyrosine kinase being investigated for the treatment of immune disorders, such as immune thrombocytopenic purpura.[A259073, A259078]
Investigational
Matched Synonyms: … -oxo-, (.alpha.e/z,3r)- ... piperidinepropanenitrile, 3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo(3,4-d)pyrimidin-1-yl)-.alpha …
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine …
N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid …
Cycloserine
Antibiotic substance produced by Streptomyces garyphalus.
Approved
Matched Synonyms: … alpha-Cycloserine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … 6-alpha-ethylchenodeoxycholic acid …
Matched Description: … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... updated its prescribing information to contraindicate the use of obeticholic acid in patients with PBC and ... The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected …
Matched Categories: … Alimentary Tract and Metabolism ... Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy …
Matched Description: … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... updated its prescribing information to contraindicate the use of obeticholic acid in patients with PBC and ... The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected …
Matched Categories: … Alimentary Tract and Metabolism ... Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy …
(3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
Experimental
Matched Name: … cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide …
{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID
Experimental
Matched Name: … {4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID …
2-(acetylamino)-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose
Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose …
Clindamycin
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Synonyms: … Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside …
Matched Description: … bacilli and gram-negative bacilli. ... used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. ... relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and …
Matched Mixtures name: … Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide ... Clindamycin and Benzoyl Peroxide …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … INFEX 100MG CÁPSULA DE GELATINA BLANDA …
Matched Description: … bacilli and gram-negative bacilli. ... used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. ... relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and …
Matched Mixtures name: … Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide ... Clindamycin and Benzoyl Peroxide …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … INFEX 100MG CÁPSULA DE GELATINA BLANDA …
4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose
Experimental
Matched Synonyms: … 4,6-Dideoxy-4-{[(1s,5r,6s)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-d-xylo-hex-5-enopyranose …
9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid
Experimental
Matched Name: … 9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid …
Matched Iupac: … 9-hydroxy-8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid …
Matched Iupac: … 9-hydroxy-8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid …
Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]
Experimental
Matched Name: … Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …
Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]
Experimental
Matched Name: … Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …
(3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
Experimental
Matched Name: … 3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide …
20-Hydroxyecdysone
Investigational
Matched Synonyms: … 20-hydroxy-.alpha.-ecdysone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Inbakicept
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Synonyms: … INTERLEUKIN 15 RECEPTOR .ALPHA. ... INTERLEUKIN 15 RECEPTOR SUBUNIT ALPHA (HUMAN IL15R.ALPHA.) (1-65)-PEPTIDE (SUSHI DOMAIN-CONTAINING) FUSION …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Inbakicept, in combination with nogapendekin alfa, mimics the actions of IL-15, stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Inbakicept, in combination with nogapendekin alfa, mimics the actions of IL-15, stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
OM-301
Investigational
Matched Synonyms: … Glycine, L-prolyl-L-prolyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-Lphenylalanyl- L-seryl-L-alpha-aspartyl-L-leucyl-L-tryptophyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-Llysyl …
Dorzolamide
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide …
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... ) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular ... [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate ... Dorzolamide and Timolol …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... ) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular ... [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate ... Dorzolamide and Timolol …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
PR1 leukemia peptide vaccine
PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … L-VALINE, L-VALYL-L-LEUCYL-L-GLUTAMINYL-L-.ALPHA. …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …
Reveglucosidase alfa
Investigational
Matched Synonyms: … 7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal alpha-glucosidase …
Methohexital
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester …
1-[Glycerolylphosphonyl]-2-[8-(2-Hexyl-Cyclopropyl)-Octanal-1-Yl]-3-[Hexadecanal-1-Yl]-Glycerol
Experimental
Matched Name: … 1-[Glycerolylphosphonyl]-2-[8-(2-Hexyl-Cyclopropyl)-Octanal-1-Yl]-3-[Hexadecanal-1-Yl]-Glycerol …
Displaying drugs 1026 - 1050 of 1108 in total