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Displaying drugs 1101 - 1125 of 1228 in total

S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine

Experimental
Matched Name: … S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine …

N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE

Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE …

Antithrombin gamma

Antithrombin gamma is under investigation in clinical trial NCT04182373 (KW-3357 Study in Patients With Early Onset Severe Preeclampsia).
Investigational
Matched Synonyms: … Human antithrombin-iii (atiii, serpin c1) expressed in fucosyl transferase-negative chinese hamster ovary …

Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and ... of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. …
Matched Salts name: … Paroxetine hydrochloride ... Paroxetine hydrochloride hemihydrate …
Matched Products: … Paroxetine Hydrochloride ... Paroxetine Hydrochloride CR ... Paroxetine Hydrochloride Anhydrous …

Gentian violet cation

A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Matched Description: … A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … El Valle Gentian Violet …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and ... angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early ... of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Salts name: … Verapamil hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil …
Matched Products: … Verapamil Hydrochloride ... Verapamil hydrochloride ... Verapamil Hydrochloride PM …

TP-252

TP-252 consists of magnesium L-lysinate bis-eicosapentaenoate, an ionizable salt of eicosapentaenoic acid (EPA), currently being investigated to treat familial adenomatous polyposis.
Investigational
Matched Synonyms: … Magnesium lysinate bis eicosapentaenoate …
Matched Description: … TP-252 consists of magnesium L-lysinate bis-eicosapentaenoate, an ionizable salt of eicosapentaenoic …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Memantine hydrochloride …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … Memantine Hydrochloride ... Memantine hydrochloride ... Mematine Hydrochloride …

Nemvaleukin alfa

Investigational
Matched Synonyms: … 75-133-interleukin 2 (125-serine) (human) fusion protein with peptide linker (gg) fusion protein with ... 75-133-Interleukin 2 [125-serine] (human) fusion protein with peptide linker (GG) fusion protein with …

Gemcitabine

Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Description: … Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [L32950] It is also being investigated in other cancer and tumour types. ... work by replacing the building blocks of nucleic acids during DNA elongation, arresting tumour growth and …
Matched Salts name: … Gemcitabine hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Gemcitabine Hydrochloride ... Gemcitabine hydrochloride ... GEMCITABINE HYDROCHLORIDE …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Salts name: … Sevelamer hydrochloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Sevelamer Hydrochloride ... Sevelamer hydrochloride …

Cilastatin

Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …

JQ1

First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate ... 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate …
Matched Iupac: … 4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …

Perenostobart

Perenostobart is an alpha-CD39 IgG4 monoclonal antibody.
Investigational
Matched Synonyms: … Immunoglobulin G4 [229-proline], anti-(human ectonucleoside triphosphate diphosphohydrolase 1) (human …

Moxifloxacin

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Salts name: … Moxifloxacin hydrochloride ... Moxifloxacin hydrochloride monohydrate …
Matched Products: … Moxifloxacin Hydrochloride ... MOXIFLOXACIN HYDROCHLORIDE ... Apo-moxifloxacin Hydrochloride …

Betaxolol

A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Salts name: … Betaxolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Betaxolol Hydrochloride …

Acebutolol

A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Description: … The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic …
Matched Salts name: … Acebutolol hydrochloride …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides ... acebutolol and thiazides …
Matched Products: … Acebutolol Hydrochloride …

(2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate

Experimental
Matched Name: … (2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate …

(3R)-4-(p-toluenesulfonyl)-1,4-thiazane-3-carboxylicacid-L-phenylalanine ethyl ester

Experimental
Matched Name: … (3R)-4-(p-toluenesulfonyl)-1,4-thiazane-3-carboxylicacid-L-phenylalanine ethyl ester …

Technetium Tc-99m mebrofenin

Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Synonyms: … Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium …
Matched Description: … uptake and fast biliary excretion, resulting in improved hepatic imaging. ... Liver and gallbladder imaging is enabled through attachment to mebrofenin as this molecule has high hepatic ... More specifically, mebrofenin is taken up into hepatocytes through the action of OATP1B1 and OATP1B3 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents ... Hepatic and Reticulo Endothelial System …

N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan

Experimental
Matched Name: … N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan …

Flavoxate

A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Description: … A drug that has been used in various urinary syndromes and as an antispasmodic. ... Its therapeutic usefulness and its mechanism of action are not clear. ... It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity …
Matched Salts name: … Flavoxate hydrochloride …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … Flavoxate Hydrochloride …

Maprotiline

Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and …
Matched Salts name: … Maprotiline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Maprotiline Hydrochloride …

Prednisolone

Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antineoplastic and Immunomodulating Agents ... Prednisolone and Prodrugs ... Sex Hormones and Insulins …
Matched Products: … STERILE PREDNISOLONE ACETATE SUSPENSION …

Nortriptyline

Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Nortriptyline Hydrochloride …
Displaying drugs 1101 - 1125 of 1228 in total