Displaying drugs 1176 - 1200 of 1276 in total
Atenolol
Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions.
Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and …
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... atenolol and nifedipine ... atenolol and thiazides ... atenolol and other diuretics …
Matched Products: … Septa-atenolol …
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... atenolol and nifedipine ... atenolol and thiazides ... atenolol and other diuretics …
Matched Products: … Septa-atenolol …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through …
Matched Description: … [A234444] On April 23 2021, the Food and Drug Administration granted accelerated approval for the antibody-drug ... and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates …
Matched Description: … [A234444] On April 23 2021, the Food and Drug Administration granted accelerated approval for the antibody-drug ... and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates …
Oxfendazole
Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Investigational
Vet approved
Matched Synonyms: … Fenbendazole sulfoxide …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. ... Oxfendazole is a sulfoxide metabolite of fenbendazole. …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. ... Oxfendazole is a sulfoxide metabolite of fenbendazole. …
6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
Experimental
Matched Name: … 6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE …
Dezamizumab
Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Investigational
Matched Synonyms: … recombinant monoclonal antibody to human serum amyloid P component ... AMYLOID P COMPONENT SERUM, SERUM AMYLOID P COMPONENT, SAP, PENTRAXIN-2, PTX2)), HUMANIZED MONOCLONAL ANTIBODY …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Crovalimab
Crovalimab is under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria).
Investigational
Matched Synonyms: … Complement c5 inhibitory humanized recycling monoclonal antibody (rg-6107 ) …
Matched Description: … under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and ... Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria …
Matched Description: … under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and ... Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria …
Piperacillin
Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Mixtures name: … PIPERACILLIN SODIUM and TAZOBACTAM SODIUM ... PIPERACILLIN SODIUM and TAZOBACTAM SODIUM ... PIPERACILLIN SODIUM and TAZOBACTAM SODIUM …
Matched Salts name: … Piperacillin sodium …
Matched Categories: … Sulfur Compounds …
Matched Products: … PIPERACILLINA SODICA …
Matched Salts name: … Piperacillin sodium …
Matched Categories: … Sulfur Compounds …
Matched Products: … PIPERACILLINA SODICA …
3,6-Anhydro-2-(hydrogen sulfate)-alpha-D-galactopyranose
Experimental
Matched Name: … 3,6-Anhydro-2-(hydrogen sulfate)-alpha-D-galactopyranose …
Minnelide
Investigational
Matched Synonyms: … -one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium …
Zalifrelimab
Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Investigational
Matched Synonyms: … A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4) …
(4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide
Experimental
Matched Name: … (4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide …
Anvatabart opadotin
Investigational
Matched Synonyms: … tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody ... monoclonal Amab788 γ1-chain), disulfide with human-Mus musculus monoclonal Amab788 κ-chain, dimer, 121,121′-dioxime …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE
Experimental
Matched Name: … BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE …
Matched Iupac: … methyl-5-[4-({[(2s,5s)-2-carboxy-2-methyl-1,3-dioxan-5-yl]oxy}carbonyl)piperazine-1-carbonyloxy]-1,3-dioxane …
Matched Iupac: … methyl-5-[4-({[(2s,5s)-2-carboxy-2-methyl-1,3-dioxan-5-yl]oxy}carbonyl)piperazine-1-carbonyloxy]-1,3-dioxane …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … Monoclonal antibody ch14.18 ... CHIMERIC ANTI-DISIALOGANGLIOSIDE (GD2) MONOCLONAL ANTIBODY (CH14.18/CHO) …
Matched Description: … By binding to GD2, dinutiximab induces antibody-dependent cell-mediated cytotoxicity and complement-dependent ... cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least ... It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Glycolipid Disialoganglioside-directed Antibody ... Glycolipid Disialoganglioside-directed Antibody Interactions …
Matched Description: … By binding to GD2, dinutiximab induces antibody-dependent cell-mediated cytotoxicity and complement-dependent ... cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least ... It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Glycolipid Disialoganglioside-directed Antibody ... Glycolipid Disialoganglioside-directed Antibody Interactions …
Obexelimab
Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … humanized anti-CD19, Fc engineered, monoclonal antibody with enhanced binding to FcyRIIb ... XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO …
(3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
Experimental
Matched Name: … (3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide …
Amatuximab
Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others.
Investigational
Matched Synonyms: … Chimeric monoclonal antibody to mesothelin …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vonlerolizumab
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … tumor necrosis factor receptor (tnfr) superfamily member 4, act35, ox40, cd134)), humanized monoclonal antibody ... receptor superfamily member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Purslane
Purslane is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Portulaca Oleracea Flower/leaf/stem Extract …
Dalteparin
Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Description: … composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than …
Matched Salts name: … Dalteparin sodium …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … DALTEPARINA SODICA INYECCIÒN 5000 UI ... DALTEPARINA SODICA 2500 UI INYECCION …
Matched Salts name: … Dalteparin sodium …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … DALTEPARINA SODICA INYECCIÒN 5000 UI ... DALTEPARINA SODICA 2500 UI INYECCION …
Candesartan cilexetil
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and …
Matched Mixtures name: … Septa-candesartan Hctz ... Septa-candesartan Hctz ... Candesartan Cilexetil and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … Septa-candesartan …
Matched Mixtures name: … Septa-candesartan Hctz ... Septa-candesartan Hctz ... Candesartan Cilexetil and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … Septa-candesartan …
Begelomab
Begelomab is a murine monoclonal antibody against CD26.
Experimental
Investigational
Matched Synonyms: … COMPLEXING PROTEIN 2, ADCP2, TP103, T CELL ACTIVATION ANTIGEN CD26, CD26)), MUS MUSCULUS MONOCLONAL ANTIBODY …
Matched Description: … Begelomab is a murine monoclonal antibody against CD26. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Begelomab is a murine monoclonal antibody against CD26. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
KITE-222
Investigational
Matched Synonyms: … An autologous chimeric antigen receptor (CAR) T-cell therapy engineered to express an antibody-derived …
2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose
Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose …
Displaying drugs 1176 - 1200 of 1276 in total