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Displaying drugs 101 - 125 of 199 in total

Momelotinib

Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding. First approved by the FDA on September 15, 2023, momelotinib is used to treat myelofibrosis. Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem cells,...
Approved
Investigational
Matched Description: … MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem …

Lipegfilgrastim

Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational

Ocrelizumab

Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational

Selinexor

Selinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound. Selinexor, in combination with bortezomib and dexamethasone, is currently approved for the treatment of multiple myeloma, a type of cancer formed from antibody-producing plasma cells.[L7117,L7120,L10145] This condition is typically treated with high dose bortezomib and dexamethasone chemotherapy followed by...
Approved
Investigational
Matched Description: … typically treated with high dose [bortezomib] and [dexamethasone] chemotherapy followed by an autologous stem-cell …

Ravulizumab

Ravulizumab is a potent and selective complement 5 (C5) inhibitor. It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells. Ravulizumab was engineered from eculizumab, another complement inhibitor, to increase the duration of action and reduce the frequency of drug administration. It works by blocking...
Approved
Investigational

Tagraxofusp

Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia coli.[A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018...
Approved
Investigational

Rizatriptan

Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved

Homosalate

Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage...
Approved
Investigational
Matched Mixtures name: … Introstem Stem Cell Active Defense …

Oxybenzone

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Mixtures name: … Introstem Stem Cell Active Defense …

Octisalate

Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Mixtures name: … Introstem Stem Cell Active Defense …

Bambusa arundinacea stem

Experimental
Matched Synonyms: … Vamsha stem ... Arundo bamboo stem ... Arundo bambos stem …
Matched Name: … Bambusa arundinacea stem …

Ephedra sinica stem

Experimental
Matched Synonyms: … Ephedra stem ... Ephedra flava stem ... Ephedra sinica stem …
Matched Name: … Ephedra sinica stem …

Platycodon grandiflorus root

Platycodon grandiflorus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Name: … Platycodon grandiflorus root …
Matched Description: … Platycodon grandiflorus root is a plant/plant extract used in some OTC (over-the-counter) products. …

Platycodon grandiflorus leaf

Platycodon grandiflorus leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Name: … Platycodon grandiflorus leaf …
Matched Description: … Platycodon grandiflorus leaf is a plant/plant extract used in some OTC (over-the-counter) products. …

Dental Mesenchymal Pulp Stem Cells

Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar teeth. Dental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties. They are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is...
Investigational
Matched Synonyms: … Dental Pulp Mesenchymal Stem Cells ... Allogenic Human Dental Pulp Stem Cells …
Matched Name: … Dental Mesenchymal Pulp Stem Cells …
Matched Description: … Dental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties. …

Stem-cell derived exosome vesicle products

Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including paracrine factors such as exosomes. Exosomes are nanometer-sized, membrane-bound vesicles secreted for the purpose of cell-cell communication. Once secreted into extracellular fluid, exosomes are taken up by their target cells or carried to distant target sites. Various bioactive...
Investigational
Matched Synonyms: … Stem-cell derived exosome vesicles ... Stem-cell derived extracellular vesicles ... Stem-cell derived extracellular vesicle products …
Matched Name: … Stem-cell derived exosome vesicle products …
Matched Description: … Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including ... products originate from multiple cellular types, including immunocytes, tumor cells, and mesenchymal stem …

Allogeneic umbilical cord mesenchymal stem cells

Investigational
Matched Synonyms: … Allogeneic umbilical cord mesenchymal stem cells ... Allogenic umbilical cord mesenchymal stem cells ... Allogeneic umbilical cord-derived mesenchymal stem cells …
Matched Name: … Allogeneic umbilical cord mesenchymal stem cells …

Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells

Human olfactory mucosa-derived mesenchymal stem cells (OM-MSCs) reside in an accessible location of the nasal cavity and have properties of multipotency and high proliferation, which contributes to high potential for regenerative medicine. In humans, OM-MSCs are derived from the olfactory mucosa which is collected in vivo through rhinoscopy techniques and...
Investigational
Matched Synonyms: … Olfactory mucosa mesenchymal stem cells ... Olfactory mucosa mesenchymal stem/stromal cells …
Matched Name: … Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells …
Matched Description: … Human olfactory mucosa-derived mesenchymal stem cells (OM-MSCs) reside in an accessible location of the …

Allogenic bone marrow-derived mesenchymal stem cells

Investigational
Matched Synonyms: … Longeveron mesenchymal stem cells ... Bone-marrow-derived mesenchymal stem cells ... Allogenic bone-marrow-derived mesenchymal stem cells …
Matched Name: … Allogenic bone marrow-derived mesenchymal stem cells …

Human Umbilical Cord Mesenchymal Stem Cells

Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over up to...
Investigational
Matched Synonyms: … Human Umbilical Cord Wharton’s Jelly-derived Mesenchymal Stem Cells …
Matched Name: … Human Umbilical Cord Mesenchymal Stem Cells …
Matched Description: … Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity ... Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures ... , more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling …

Placental Mesenchymal Stem Cells

The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs). It can be obtained relatively easily as medical waste from which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem cells. The placental MSCs (pMSCs) are...
Investigational
Matched Name: … Placental Mesenchymal Stem Cells …
Matched Description: … The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs) ... which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem …

Skin-derived ABCB5-positive Mesenchymal Stem cells

Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 (Allogeneic Abcb5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase Iib)).
Investigational
Matched Synonyms: … Skin-derived ABCB5+ Mesenchymal Stem cells …
Matched Name: … Skin-derived ABCB5-positive Mesenchymal Stem cells …
Matched Description: … Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 …

Allogenic fetal mesenchymal stem cells

Investigational
Matched Name: … Allogenic fetal mesenchymal stem cells …

Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media

Umbilical-cord derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and anti-inflammatory properties. In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic. The condition medium (CM) derived from these MSCs has also been implicated...
Investigational
Matched Synonyms: … Allogeneic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media ... Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …

Human Menstrual Blood-derived Stem Cells

Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner cell mass of blastocysts while ASCs are deposited into adult tissues with restricted...
Investigational
Matched Name: … Human Menstrual Blood-derived Stem Cells …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... MenSCs are special compared to older methods of adult stem cell extraction such as bone marrow stem cell ... Because this is a non-invasive way to obtain stem cells, it is simple and easy to obtain the stem cells …
Displaying drugs 101 - 125 of 199 in total