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Displaying drugs 151 - 171 of 171 in total

CEP-1347

CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and after transplantation.
Investigational
Matched Iupac: … methyl (15S,16S,18S)-10,23-bis[(ethylsulfanyl)methyl]-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[ …
Matched Description: … CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults ... to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and …

Nonivamide

Nonivamide is found in herbs and spices. It is an alkaloid from the Capsicum species. The structures of DB06774 and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus nonanoic acid) . Nonivamide is a flavoring ingredient. Nonivamide is an...
Investigational
Matched Iupac: … N-[(4-hydroxy-3-methoxyphenyl)methyl]nonanamide …
Matched Description: … of the side chain (8-methyl nonenoic acid versus nonanoic acid) [F31]. ... It is naturally found in chili peppers but manufactured to produce a synthetic form for various pharmacologic ... Nonivamide is an organic compound and a capsaicinoid. …

Cyclofenil

Experimental
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](cyclohexylidene)methyl}phenyl acetate …
Matched Categories: … Ovulation Stimulants, Synthetic ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Oxitropium

Oxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Iupac: … (1R,2R,4S,5S,7S)-9-ethyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo[3.3.1.0 …
Matched Categories: … Synthetic Anticholinergics, Quaternary Ammonium Compounds …

Phenothrin

Experimental
Matched Iupac: … (3-phenoxyphenyl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate …
Matched Categories: … Synthetic Compounds ... Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …

Bevonium

Experimental
Matched Iupac: … 2-{[(2-hydroxy-2,2-diphenylacetyl)oxy]methyl}-1,1-dimethylpiperidin-1-ium …
Matched Categories: … Synthetic Anticholinergics, Quaternary Ammonium Compounds ... bevonium and analgesics ... Alimentary Tract and Metabolism ... bevonium and psycholeptics …

AS-8112

AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.
Experimental
Matched Iupac: … 5-bromo-N-[(6R)-1-ethyl-4-methyl-1,4-diazepan-6-yl]-2-methoxy-4-(methylamino)benzamide …
Matched Description: … AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes ... D2 and D3, and the serotonin receptor 5-HT3. ... It has been shown to exert potent antiemetic effects in animal studies and has been investigated for …

Oxabolone cipionate

Oxabolone cipionate is the C17β cypionate ester and a prodrug of DB01500. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone). It is considered as a performance enhancing drug thus is prohibited from use in sports.
Experimental
Matched Iupac: … (1S,2R,10R,11S,14S,15S)-6-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl 3-cyclopentylpropanoate …
Matched Description: … Oxabolone cipionate is the C17β cypionate ester and a prodrug of [DB01500]. ... A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone). …
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Ularitide

Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Iupac: … ]-31,40-bis(3-carbamimidamidopropyl)-19-(2-carbamoylethyl)-34-(carboxymethyl)-16-(hydroxymethyl)-22-methyl …
Matched Description: … Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is ... involved in regulating blood pressure and the excretion of water and sodium from the kidneys. ... Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Dihydromorphine

A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]
Experimental
Illicit
Matched Iupac: … (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10 …
Matched Categories: … Semi-synthetic Opioids …

Allylestrenol

A synthetic steroid with progestational activity. It is widely marketed throughout Europe, including Russia and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably not in the United States or Canada.
Experimental
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-11a-methyl-1-(prop-2-en-1-yl)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H …
Matched Description: … A synthetic steroid with progestational activity. ... It is widely marketed throughout Europe, including Russia and many other European countries, and is also ... available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Cimetropium

Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which partially accounts for its antispasmodic activity. It has never been approved for use in the U.S. or Canada.
Experimental
Investigational
Matched Iupac: … (1R,2R,4S,5S,7S)-9-(cyclopropylmethyl)-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo …
Matched Description: … Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. ... It is a potent antimuscarinic and an effective antispasmodic drug. …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain …

Promestriene

Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of Hypospadias. It is a synthetic estrogen analog, which is used in topical estrogen therapy. Promestriene’s potential for treating vaginal atrophy symptoms associated with aromatase inhibitor treatment would be precluded if its minimal absorption leads to estrogen-like...
Investigational
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-1-methoxy-11a-methyl-7-propoxy-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta …
Matched Description: … It is a synthetic estrogen analog, which is used in topical estrogen therapy. ... Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of ... treatment would be precluded if its minimal absorption leads to estrogen-like effects on cell proliferation and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Norethindrone enanthate

Experimental
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-1-ethynyl-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H, …
Matched Categories: … Contraceptives, Oral, Synthetic …

Norgestrienone

Experimental
Matched Iupac: … (1R,3aS,3bS,11aS)-1-ethynyl-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,11aH-cyclopenta[a]phenanthren …
Matched Categories: … Contraceptives, Oral, Synthetic ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Combination Contraceptives (with Estrogen and derivatives) …

Queuine

Queuine is a derivative of 7-Deazaguanine. Bacteria possess the exclusive ability to synthesize queuine, which is then salvaged and passed on to plants and animals. Quantities of queuine have been found in tomatoes, wheat, coconut water, and milk from humans, cows, and goats. Humans salvage and recover queuine from either...
Experimental
Nutraceutical
Matched Iupac: … (1R,2S,5S)-5-[({4-hydroxy-2-imino-1H,2H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}methyl)amino]cyclopent-3-ene- …
Matched Description: … and goats. ... plants and animals. ... Humans salvage and recover queuine from either ingested food or the gut flora. …

Otilonium

Experimental
Investigational
Matched Iupac: … diethyl(methyl)(2-{4-[2-(octyloxy)benzamido]benzoyloxy}ethyl)azanium …
Matched Categories: … Synthetic Anticholinergics, Quaternary Ammonium Compounds ... Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents ... otilonium bromide and psycholeptics …

Sulbutiamine

Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives. Although its clinical efficacy is not yet...
Experimental
Matched Iupac: … (3E)-4-{N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamido}-3-{[(2E)-2-{N-[(4-amino-2-methylpyrimidin ... -5-yl)methyl]formamido}-5-[(2-methylpropanoyl)oxy]pent-2-en-3-yl]disulfanyl}pent-3-en-1-yl 2-methylpropanoate …
Matched Description: … Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is ... While its other uses include improvement of erectile dysfunction and reduction of psycho-behavioural ... inhibition, sulbutiamine showed evidence of modulatory effect on dopaminergic and glutamatergic cortical …
Matched Categories: … Alimentary Tract and Metabolism …

CZEN 002

CZEN-002 is a novel, non-azole anti-fungal synthetic octapeptide, derived from alpha-Melanocyte-Stimulating Hormone (a-MSH). CZEN-002 modulates inflammatory and immune responses. It has also been shown to kill Candida albicans (C. albicans), a single-celled fungal organism that causes a variety of infections, including vaginitis. This organism can invade tissues and produce fatal...
Investigational
Matched Iupac: … amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl …
Matched Description: … CZEN-002 modulates inflammatory and immune responses. ... CZEN-002 is a novel, non-azole anti-fungal synthetic octapeptide, derived from alpha-Melanocyte-Stimulating ... This organism can invade tissues and produce fatal infections in individuals with compromised immune …

Mevastatin

Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Iupac: … (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen …
Matched Description: … The compound was proposed to bind to the reductase enzyme and was named compactin. ... It has served as one of the lead compounds for the development of the synthetic compounds used today. …

Nabiximols

Nabiximols (tradename Sativex®) is a whole plant extract from the Cannabis species Cannabis sativa L. that has been purified into the active components CBD (cannabidiol) and THC (delta-9-tetrahydrocannabinol). For trademark purposes, purified CBD is branded as Nabidiolex®, while THC is purified as the product Tetrabinex®. Sativex® is available in a...
Investigational
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol; 2-[(1R,6R)-3-methyl-6- …
Matched Description: … off-label" for the management of many medical conditions, THC is currently commercially available in synthetic ... , and physiological effects. ... changes in emotional and cognitive processes. …
Matched Categories: … Cannabinoids and similars …
Displaying drugs 151 - 171 of 171 in total