Displaying drugs 2301 - 2325 of 3468 in total
PIK-75
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Synonyms: … Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide …
Matched Description: … PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097] …
Matched Categories: … Sulfur Compounds …
Matched Description: … PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097] …
Matched Categories: … Sulfur Compounds …
ATI-1013
ATI-1013 is a fully human nicotine-specific monoclonal antibody.
Investigational
Matched Synonyms: … Fully human nicotine-specific monoclonal antibody …
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
Celastrol
Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.
Investigational
Matched Synonyms: … 24-nor-d:a-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo- ... 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, (9.beta.,13.alpha …
Matched Iupac: … ,14b-tetradecahydropicene-2-carboxylic acid ... (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a …
Matched Description: … Celastrol is a pentacyclic triterpenoid isolated from the root extracts of _Tripterygium wilfordii_. …
Matched Iupac: … ,14b-tetradecahydropicene-2-carboxylic acid ... (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a …
Matched Description: … Celastrol is a pentacyclic triterpenoid isolated from the root extracts of _Tripterygium wilfordii_. …
Epicaptopril
Experimental
Matched Synonyms: … (2S)-1-((2R)-2-Methyl-3-sulfanylpropanoyl)pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Matched Iupac: … (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
RU82197
Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid …
Matched Iupac: … (3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic acid …
Matched Iupac: … (3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic acid …
Dicyclomine
Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome.[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small...
Approved
Matched Synonyms: … Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester …
Matched Description: … of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder ... Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor ... and irritable bowel syndrome. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... Cyclohexanecarboxylic Acids …
Matched Description: … of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder ... Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor ... and irritable bowel syndrome. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... Cyclohexanecarboxylic Acids …
Olinvacimab
Olinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ttac- ... Fully human monoclonal antibody targets vascular endothelial growth factor receptor 2 ... 0001 heavy chain), disulfide with human monoclonal ttac-0001 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Proteins ... Serum Globulins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Proteins ... Serum Globulins …
BOC-GAMMA-D-GLU-L-LYS(CBZ)-D-BOROALA
Experimental
Matched Name: … BOC-GAMMA-D-GLU-L-LYS(CBZ)-D-BOROALA …
Matched Iupac: … (1S)-1-(dihydroxyboranyl)ethyl]carbamoyl}pentyl]carbamoyl}-2-{[(tert-butoxy)carbonyl]amino}butanoic acid …
Matched Iupac: … (1S)-1-(dihydroxyboranyl)ethyl]carbamoyl}pentyl]carbamoyl}-2-{[(tert-butoxy)carbonyl]amino}butanoic acid …
Irosustat
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Synonyms: … 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate …
Matched Iupac: … 6-oxo-6H,7H,8H,9H,10H,11H-cyclohepta[c]chromen-3-yl sulfamate …
Matched Description: … Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast …
Matched Categories: … Sulfur Acids ... Steryl-Sulfatase, antagonists & inhibitors ... Sulfur Compounds ... Acids ... Acids, Noncarboxylic …
Matched Iupac: … 6-oxo-6H,7H,8H,9H,10H,11H-cyclohepta[c]chromen-3-yl sulfamate …
Matched Description: … Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast …
Matched Categories: … Sulfur Acids ... Steryl-Sulfatase, antagonists & inhibitors ... Sulfur Compounds ... Acids ... Acids, Noncarboxylic …
EDI-200
EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational
Matched Synonyms: … HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Blood Proteins ... Serum Globulins …
Matched Description: … human receptor binding domain of ectodysplasin-A1. ... EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Blood Proteins ... Serum Globulins …
Timolumab
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion …
Matched Description: … Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Proteins ... Serum Globulins …
Matched Description: … Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Proteins ... Serum Globulins …
Tacrolimus
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Iupac: … (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl …
Matched Description: … drug whose main use is after organ transplant to reduce the activity of the patient's immune system and ... the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and ... This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … ADVAGRAF 1 MG UZUN SALIMLI SERT KAPSÜL, 30 ADET ... ADVAGRAF 1 MG UZUN SALIMLI SERT KAPSÜL, 60 KAPSÜL ... ADVAGRAF 5 MG UZUN SALIMLI SERT KAPSÜL, 30 KAPSÜL …
Matched Description: … drug whose main use is after organ transplant to reduce the activity of the patient's immune system and ... the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and ... This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … ADVAGRAF 1 MG UZUN SALIMLI SERT KAPSÜL, 30 ADET ... ADVAGRAF 1 MG UZUN SALIMLI SERT KAPSÜL, 60 KAPSÜL ... ADVAGRAF 5 MG UZUN SALIMLI SERT KAPSÜL, 30 KAPSÜL …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion ... protein with human tumor necrosis factor .alpha., trimer …
L-gamma-glutamyl-S-(naphthalen-1-ylmethyl)-L-cysteinylglycine
Experimental
Matched Name: … L-gamma-glutamyl-S-(naphthalen-1-ylmethyl)-L-cysteinylglycine …
Matched Iupac: … 4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(naphthalen-1-yl)methyl]sulfanyl}ethyl]carbamoyl}butanoic acid …
Matched Iupac: … 4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(naphthalen-1-yl)methyl]sulfanyl}ethyl]carbamoyl}butanoic acid …
N-[12-(1H-imidazol-1-yl)dodecanoyl]-L-leucine
Experimental
Matched Name: … N-[12-(1H-imidazol-1-yl)dodecanoyl]-L-leucine …
Matched Iupac: … (2S)-2-[12-(1H-imidazol-1-yl)dodecanamido]-4-methylpentanoic acid …
Matched Iupac: … (2S)-2-[12-(1H-imidazol-1-yl)dodecanamido]-4-methylpentanoic acid …
Karaya gum
Karaya gum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Sterculia urens resin …
Matched Categories: … Alimentary Tract and Metabolism ... Equipment and Supplies ... Increased Histamine Release …
Matched Categories: … Alimentary Tract and Metabolism ... Equipment and Supplies ... Increased Histamine Release …
Human Recombinant Bone Morphogenetic Protein 4
Investigational
Matched Synonyms: … RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Human Embryonic Stem Cell-derived Astrocytes
Investigational
Matched Name: … Human Embryonic Stem Cell-derived Astrocytes …
Recombinant human palmitoyl protein thioesterase-1
Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …
Propagermanium
Investigational
Matched Synonyms: … 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid ... Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis- …
Matched Categories: … Interferon Inducers ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Categories: … Interferon Inducers ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Bis(2,2-dimethylpropanoyloxymethyl) VK-0214
Investigational
Matched Synonyms: … 2,2-dimethylpropanoic acid 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy) ... Propanoic acid, 2,2-dimethyl-, 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy …
Tridecactide
Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. Tridecactide, along with metenkefalin, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … alpha-1-13-corticotropin, human …
Matched Iupac: … hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid …
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte ... stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. …
Matched Iupac: … hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid …
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte ... stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. …
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and …
Matched Salts name: … Iptacopan hydrochloride monohydrate …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and …
Matched Salts name: … Iptacopan hydrochloride monohydrate …
CBP-501
Investigational
Matched Synonyms: … D-arginine, 4-benzoyl-d-phenylalanyl-d-seryl-d-tryptophyl-d-seryl-2,3,4,5,6-pentafluoro-d-phenylalanyl …
Matched Iupac: … carbamimidamidopentanamido]-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intracellular Signaling Peptides and Proteins …
Matched Iupac: … carbamimidamidopentanamido]-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intracellular Signaling Peptides and Proteins …
Rugonersen
Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of Angelman Syndrome.
Investigational
Matched Synonyms: … UBE3A antisense oligonucleotide with locked nucleic acids …
Matched Description: … Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of …
Matched Description: … Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of …
Displaying drugs 2301 - 2325 of 3468 in total