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Displaying drugs 1 - 25 of 15286 in total
Approved
Experimental
Matched Synonyms: … (+/-)-camphor ... DL-camphor ... Gum camphor
Matched Name: … Synthetic camphor
Matched Mixtures name: … Major Camphor and Phenol ... CAMPHOR (SYNTHETIC) and PHENOL ... CAMPHOR, EUCALYPTUS OIL and MENTHOL …
Matched Products: … Natural 17 Muscle ... Camphor ... De La Cruz Camphor
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Synonyms: … Natural wintergreen oil ... Methyl salicylate ... Methyl 2-hydroxybenzoate …
Matched Name: … Methyl salicylate …
Matched Iupac: … methyl 2-hydroxybenzoate …
Matched Description: … For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating ... Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many ... It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. …
Matched Mixtures name: … Sunset Pain Relief Heating Camphor and Amino Acids ... Menthol and Methyl Salicylate ... Menthol and Methyl Salicylate …
Matched Products: … Methyl Salicylate ... Neuro Max Pain and Muscle Relief Gel ... SmartRx Natural Pain Relief Sleeve WRIST …
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used ... meningococcal disease, which is caused by bacteria _Neisseria meningitidis_ entering the bloodstream and ... invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and
Approved
Matched Synonyms: … Phenyl PAS ... Phenyl aminosalicylate ... Phenyl 4-aminosalicylate …
Matched Name: … Phenyl aminosalicylate …
Matched Iupac: … phenyl 4-amino-2-hydroxybenzoate …
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen. Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.
Approved
Matched Synonyms: … N-Cyclohexyl-N'-phenyl-p-phenylendiamine ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine ... N-cyclohexyl-N'-phenyl-p-phenylenediamine …
Matched Name: … N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine …
Matched Description: … It is also a dermatological sensitizer and allergen. ... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. ... Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test …
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Synonyms: … Methyl benzylidene camphor ... 4-methylbenzylidene camphor ... 3-(4-methylbenzylidene)camphor
Matched Description: … Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic ... Its tradenames include Eusolex 6300 (Merck) and Parsol 5000 (DSM). ... human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and
Matched Mixtures name: … Natural Sun AQ Body and Family Mild Sun Milk ... Outback 2-in-1 Insect Repellent and Protective Sunscreen ... Secret Key Natural Cc Cushion Spf50 Pa / 02 Natural Cc …
Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY; BISPECIFIC …
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Synonyms: … N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide …
Matched Iupac: … N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4,5-trimethoxybenzamide …
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.[A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.[L44918,L44948] It received a similar approval in the EU in September 2023. Elacestrant binds to estrogen receptor-alpha (ERα)...
Approved
Investigational
Matched Synonyms: … (2R)-2-(2-(ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-ol ... (6R)-6-(2-(ethyl((4-(2- (ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)- 5,6,7,8-tetrahydronaphthalen ... 2-naphthalenol, 6-(2-(ethyl((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydro …
Matched Iupac: … (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen …
Matched Description: … Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist. ... degrader (SERD) thanks to its ability to block the transcriptional activity of the ER and promote its ... [L49334] Elacestrant binds to estrogen receptor-alpha (ERα) and acts as a selective estrogen receptor …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …
Approved
Investigational
Matched Synonyms: … Natural graphite …
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide ... N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … in tumour cell proliferation and tumour angiogenesis. ... Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl} …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and ... rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Synonyms: … 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone ... 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. ... doses of 125, 25, and 50 mg is approximately 93%. ... The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … α-methyl-4-(2-thienylcarbonyl)benzeneacetic acid ... 2-(4-(2-Thenoyl)phenyl)propionsäure ... (±)-2-(p-(2-thenoyl)phenyl)propionic acid …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … [(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and ... member of the oxazolidinone class of antibiotics, which includes the previously approved [linezolid] and
Approved
Matched Synonyms: … 4-(n-methyl-2,2-dichloroacetamido)phenyl 2-furoate …
Matched Iupac: … 4-(2,2-dichloro-N-methylacetamido)phenyl furan-2-carboxylate …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including highly emetogenic chemotherapy. Netupitant is a neurokinin 1 receptor antagonist. The combination drug is marketed by Eisai...
Approved
Investigational
Matched Synonyms: … 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl …
Matched Iupac: … 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin …
Matched Description: … The combination drug is marketed by Eisai Inc. and Helsinn Therapeutics (U.S.) ... approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and ... delayed vomiting and nausea associated with cancer chemotherapy including highly emetogenic chemotherapy …
Matched Categories: … Netupitant and prodrug …
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Phenyl alcohol ... Phenyl hydroxide …
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Major Camphor and Phenol ... CAMPHOR (SYNTHETIC) and PHENOL ... Poison Oak and Ivy …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Displaying drugs 1 - 25 of 15286 in total