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Displaying drugs 226 - 250 of 14792 in total

Pemetrexed

Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for...

Approved

Investigational

Matched Description: … Its use in non-small cell lung cancer has also been investigated. ... Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the ... It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Sorbitol

A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.

Approved

Matched Description: … A polyhydric alcohol with about half the sweetness of sucrose. ... It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for ... Sorbitol occurs naturally and is also produced synthetically from glucose. …
Matched Mixtures name: … Cleanse Gut And Colon ... INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) …
Matched Categories: … Indicators and Reagents ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Bismuth subcitrate potassium

A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).

Approved

Investigational

Matched Description: … A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD). …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... bismuth subcitrate, tetracycline and metronidazole ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Birch bark extract

Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...

Approved

Experimental

Matched Description: … Some of the compounds identified in it include betulin, [lupeol], [betulinic acid], oleanolic acid, and ... of trees used for production are _Betula pendula_ Roth (silver birch) and _Betula pubescens_ Ehrh. ... [A249945] Birch bark extract is obtained from the white part of the birch tree bark, and the main species …

Glofitamab

Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488] Glofitamab was approved...

Approved

Investigational

Matched Description: … [L45768] The most common type of non-Hodgkin lymphoma,[L45763] DLBCL is relatively sensitive to chemotherapy ... systemic therapy under accelerated approval based on response rate and durability of response. ... It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Bicalutamide

Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.

Approved

Matched Description: … It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide ... Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. …
Matched Categories: … Antiandrogens, non-steroidal ... Hormones and Related Agents ... leuprorelin and bicalutamide ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …

Milnacipran

Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment of depression [F3928, F3934, A175786, A175951]. Furthermore, in 2009 the US FDA approved milnacipran for the additional indication of...

Approved

Investigational

Matched Description: … robust evidence of efficacy, insufficient demonstration of maintenance of effect, and other concerns ... Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents ... in this category was originally developed for and continues to be approved and indicated for the treatment …
Matched Categories: … Analgesics, Non-Narcotic ... Milnacipran and enantiomer ... Serotonin and Noradrenaline Reuptake Inhibitors ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Choline C-11

Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized tomography (CT) or magnetic resonance imaging.

Approved

Matched Description: … pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized ... Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of …

Conivaptan

Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).

Approved

Investigational

Matched Description: … Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). ... Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2). ... It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate …

Chlormezanone

A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.

Approved

Investigational

Withdrawn

Matched Description: … A non-benzodiazepine that is used in the management of anxiety. ... It has been suggested for use in the treatment of muscle spasm. …
Matched Categories: … Oxazol, Thiazine, and Triazine Derivatives …

Encorafenib

Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts cell division, differentiation, and secretion. Mutations in this gene,...

Approved

Investigational

Matched Description: … , thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of the lung ... have been isolated in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer ... [L3344] On June 27, 2018, the Food and Drug Administration approved encorafenib and [binimetinib] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Benorilate

Approved

Matched Categories: … Salicylic Acid and Derivatives ... Analgesics, Non-Narcotic ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal …

Bleomycin

A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.

Approved

Investigational

Matched Description: … A2 and B2 (B2 CAS # 9060-10-0). ... A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin ... It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …