Displaying drugs 2551 - 2575 of 2584 in total
Dactinomycin
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … DILACTONE ACTINOMYCIN D ACID …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
(4S)-5-[[(2S)-1-[[(2S)-1-Amino-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-4-benzamido-5-oxopentanoic acid
Experimental
Matched Name: … yl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-4-benzamido-5-oxopentanoic acid …
Matched Iupac: … ethyl]carbamoyl}-2-{4-[difluoro(phosphono)methyl]phenyl}ethyl]carbamoyl}-4-(phenylformamido)butanoic acid …
Matched Iupac: … ethyl]carbamoyl}-2-{4-[difluoro(phosphono)methyl]phenyl}ethyl]carbamoyl}-4-(phenylformamido)butanoic acid …
Ceftaroline fosamil
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria:
Acute bacterial skin and skin structure infections.
Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and …
Matched Categories: … beta Lactam Antibiotics …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and …
Matched Categories: … beta Lactam Antibiotics …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … -HYDROXY-, 15-ETHER WITH N-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA. ... N2-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA. …
Matched Iupac: … 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-amido}hexanoic acid …
Matched Description: … Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-amido}hexanoic acid …
Matched Description: … Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Intermedine
Investigational
Matched Synonyms: … N-acetyl-acth(1-13)-amide ... Valinamide, acetyl-l-seryl-l-tyrosyl-l-seryl-l-methionyl-l-glutamyl-l-histidyl-l-phenylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Erythromycin
Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Description: … antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and ... the macrolide group of antibiotics which consists of [Azithromycin], [Clarithromycin], [Spiramycin] and ... [L5245,L7261] It is available for administration in various forms, including intravenous, topical, and …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … Spotex …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … Spotex …
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine …
(E)-(S)-4-[(S)-4-METHYL-2-((S)-3-METHYL-2{(S)-2-[(5-METHYL-ISOXAZOLE-3- CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-PENTANOYLAMINO]-5-((S)-2- OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID ETHYL ESTER
Experimental
Matched Name: … CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-PENTANOYLAMINO]-5-((S)-2- OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID …
Ceftolozane
Ceftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin. It was approved by the FDA in 2014 for use in combination with Tazobactam for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections. The manufacturer of this drug is Cubist Pharmaceuticals. Most recently, in June 2019,...
Approved
Investigational
Matched Synonyms: … methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl …
Matched Description: … and mortality in hospitalized patients and the use of ceftolozane-tazobactam offers effective activity ... combination with [Tazobactam] for the treatment of serious infections, such as intra-abdominal infections and ... 2019, ceftolozane-tazobactam was approved for the treatment of hospital-acquired bacterial pneumonia and …
Matched Description: … and mortality in hospitalized patients and the use of ceftolozane-tazobactam offers effective activity ... combination with [Tazobactam] for the treatment of serious infections, such as intra-abdominal infections and ... 2019, ceftolozane-tazobactam was approved for the treatment of hospital-acquired bacterial pneumonia and …
Clindamycin
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Description: … bacilli and gram-negative bacilli. ... used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. ... relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and …
Matched Mixtures name: … Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide ... Clindamycin Phosphate and Benzoyl Peroxide …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … LACIN CAPSULE (150 MG) …
Matched Mixtures name: … Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide ... Clindamycin Phosphate and Benzoyl Peroxide …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … LACIN CAPSULE (150 MG) …
(E)-(4S,6S)-8-METHYL-6-((S)-3-METHYL-2-{(S)-2-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID BENZYL ESTER
Experimental
Matched Name: … CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID …
(E)-(4S,6S)-6-((S)-2-{(S)-2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID ETHYL ESTER
Experimental
Matched Name: … METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID …
N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE
Experimental
Matched Name: … N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE …
Matched Iupac: … acid ... 4-{[(1S)-1-[hydroxy({[(2-phenylethyl)carbamoyl]methoxy})phosphoryl]-2-phenylethyl]carbamoyl}butanoic …
Matched Iupac: … acid ... 4-{[(1S)-1-[hydroxy({[(2-phenylethyl)carbamoyl]methoxy})phosphoryl]-2-phenylethyl]carbamoyl}butanoic …
N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid
Experimental
Matched Name: … carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid …
Matched Iupac: … -5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-5-yl}prop-2-enamido]phenyl}formamido)pentanedioic acid …
Matched Iupac: … -5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-5-yl}prop-2-enamido]phenyl}formamido)pentanedioic acid …
ST-101
ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational
Matched Synonyms: … ST-101 (D-AMINO ACID PEPTIDE) …
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
Norgestimate
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Synonyms: … Dexnorgestrel Acetime …
Matched Mixtures name: … Norgestimate and Ethinyl Estradiol ... Norgestimate and Ethinyl Estradiol ... Norgestimate and Ethinyl Estradiol …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... norgestimate and estrogen ... Genito Urinary System and Sex Hormones ... norgestimate and ethinylestradiol ... norgestimate and ethinylestradiol …
Matched Mixtures name: … Norgestimate and Ethinyl Estradiol ... Norgestimate and Ethinyl Estradiol ... Norgestimate and Ethinyl Estradiol …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... norgestimate and estrogen ... Genito Urinary System and Sex Hormones ... norgestimate and ethinylestradiol ... norgestimate and ethinylestradiol …
(3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine
Experimental
Matched Name: … (3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine …
Matched Iupac: … ]butanoic acid ... (2S,3R)-4-{[2-(3,4-dihydroxyphenyl)acetyl]oxy}-2-[(2-formylindolizin-3-yl)amino]-3-methyl-3-[(S)-sulfino …
Matched Iupac: … ]butanoic acid ... (2S,3R)-4-{[2-(3,4-dihydroxyphenyl)acetyl]oxy}-2-[(2-formylindolizin-3-yl)amino]-3-methyl-3-[(S)-sulfino …
1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine
Experimental
Matched Name: … 1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine …
[1-(4-Fluorobenzyl)Cyclobutyl]Methyl (1s)-1-[Oxo(1h-Pyrazol-5-Ylamino)Acetyl]Pentylcarbamate
Experimental
Matched Name: … [1-(4-Fluorobenzyl)Cyclobutyl]Methyl (1s)-1-[Oxo(1h-Pyrazol-5-Ylamino)Acetyl]Pentylcarbamate …
3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol
Experimental
Matched Name: … 3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol …
(2S)-2-({4-[(2S)-1-(2-Amino-4-oxo-1,4-dihydro-6-quinazolinyl)-3-{[2-({(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]tetrahydro-2-furanyl}amino)-2-oxoethyl]amino}-2-hydroxy-2-propanyl]benzoyl}ami no)pentanedioic acid
Experimental
Matched Name: … methyl]tetrahydro-2-furanyl}amino)-2-oxoethyl]amino}-2-hydroxy-2-propanyl]benzoyl}ami no)pentanedioic acid …
Matched Iupac: … phosphonooxy)methyl]oxolan-2-yl]carbamoyl}methyl)amino]-2-hydroxypropan-2-yl]phenyl}formamido)pentanedioic acid …
Matched Iupac: … phosphonooxy)methyl]oxolan-2-yl]carbamoyl}methyl)amino]-2-hydroxypropan-2-yl]phenyl}formamido)pentanedioic acid …
Edotreotide yttrium Y-90
Investigational
Matched Synonyms: … Yttrium Y-90 n-((4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)acetyl)-d-phe-cys-tyr-d-trp-lys-thr-cys-thr …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE)
Experimental
Matched Name: … 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) …
N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE
Experimental
Matched Name: … N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE …
1-[2-(3-ACETYL-2-HYDROXY-6-METHOXY-PHENYL)-CYCLOPROPYL]-3-(5-CYANO-PYRIDIN-2-YL)-THIOUREA
Experimental
Matched Name: … 1-[2-(3-ACETYL-2-HYDROXY-6-METHOXY-PHENYL)-CYCLOPROPYL]-3-(5-CYANO-PYRIDIN-2-YL)-THIOUREA …
Matched Iupac: … 3-[(1R,2R)-2-(3-acetyl-2-hydroxy-6-methoxyphenyl)cyclopropyl]-1-(5-cyanopyridin-2-yl)thiourea …
Matched Iupac: … 3-[(1R,2R)-2-(3-acetyl-2-hydroxy-6-methoxyphenyl)cyclopropyl]-1-(5-cyanopyridin-2-yl)thiourea …
Displaying drugs 2551 - 2575 of 2584 in total