Displaying drugs 4576 - 4600 of 11432 in total
Brofaromine
Experimental
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Suramin
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin...
Investigational
Matched Description: … A polyanionic compound with an unknown mechanism of action. …
Benzquinamide
Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
Withdrawn
Matched Iupac: … 3-(diethylcarbamoyl)-9,10-dimethoxy-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-yl acetate …
Matched Description: … Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative …
Matched Description: … Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative …
Gluco-Phenylimidazole
Experimental
Matched Iupac: … (5R,6R,7S,8S)-5-(hydroxymethyl)-2-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …
TRIAZOLOPYRIMIDINE
Experimental
Matched Iupac: … 7-(3-bromophenyl)-5-{[(pyridin-4-yl)methyl]amino}-3H-4lambda5-[1,2,4]triazolo[1,5-a]pyrimidin-4-ylium …
Phosphorylcolamine
Experimental
Guanine
Experimental
Thymine
Experimental
Cellobiose
A disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose. [PubChem]
Experimental
Matched Description: … A disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cacodylic acid
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Leucine
An essential branched-chain amino acid important for hemoglobin formation.
Investigational
Nutraceutical
Ritanserin
Ritanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
Investigational
Matched Iupac: … 6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin …
Retagliptin
Retagliptin is under investigation in clinical trial NCT02822534 (The Pharmacokinetics and Pharmacodynamics Study of Single and Multiple Dose of SP2086 in Type 2 Diabetes Patients).
Investigational
Matched Iupac: … methyl 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-5H,6H,7H,8H-imidazo[1,5-a] …
Cilazaprilat
Experimental
Matched Iupac: … (1S,9S)-9-{[(1S)-1-carboxy-3-phenylpropyl]amino}-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine- …
SARS-CoV-2 mRNA vaccine
SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated mRNA encoding the receptor binding domain of SARS-CoV-2 . It is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed by Abogen Biosciences, Walvax Biotechnolgoy Co., Ltd....
Investigational
Matched Description: … SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated ... by Abogen Biosciences, Walvax Biotechnolgoy Co., Ltd. and the People’s Liberation Army (PLA) Academy ... It is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed …
RC118
RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
Investigational
Matched Description: … RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal …
Aetiocholanolone
The 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine. [PubChem]
Experimental
Matched Iupac: … (3aS,3bR,5aR,7R,9aS,9bS,11aS)-7-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-one …
Matched Description: … Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including …
Matched Description: … Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including …
ANILINOMETHYL GLUCO-PHENYLIMIDAZOLE
Experimental
Matched Iupac: … (5R,6R,7S,8S)-5-(hydroxymethyl)-2-[(phenylamino)methyl]-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …
Ecabet
Ecabet is a prescription eye drop for the treatment of dry eye syndrome. Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss...
Investigational
Matched Description: … Ecabet is a prescription eye drop for the treatment of dry eye syndrome. ... Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced ... Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss from tear …
Matched Categories: … Pepsin A, antagonists & inhibitors ... Compounds used in a research, industrial, or household setting …
Matched Categories: … Pepsin A, antagonists & inhibitors ... Compounds used in a research, industrial, or household setting …
DCLL-9718S
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Description: … DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants …
ISS-1018
ISS 1018 is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity. ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin-12 (IL-12), and tumor necrosis factor - alpha (TNF-alpha) by plasmacytoid dendritic cells (pDC)....
Investigational
Matched Description: … ISS 1018 CpG ODN promotes antigen presentation and co-stimulatory molecule expression. ... ISS 1018 is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory ... ISS 1018 is currently being investigated in combination with HBsAg vaccine as a prophylactic treatment …
Cerulenin
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Description: … In sterol synthesis, inhibits HMG-CoA synthetase activity. …
Vitamin B6 Complexed with 2-Amino-Hexanoic Acid
Experimental
Icaridin
Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and a member of the piperidine chemical family. Piperidines are structural components of piperine, which is a plant extract from the genus _Piper _, or pepper. Icaridin has been commonly used as a topically-applied insect repellent...
Experimental
Matched Description: … and a member of the piperidine chemical family. ... Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine ... Piperidines are structural components of [piperine], which is a plant extract from the genus _Piper _ …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tridecactide
Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. Tridecactide, along with metenkefalin, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte …
Displaying drugs 4576 - 4600 of 11432 in total