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Displaying drugs 26 - 50 of 8595 in total

Ziprasidone

Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Categories: … Antidepressive Agents ... Dopamine Agents ... Antipsychotic Agents ... Anticholinergic Agents ... Serotonin Agents …
Matched Products: … Truemed Group LLC …

Opium

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … Opium is the first substance of the diverse group of the opiates. ... of phenanthrenes and alkaloids that have no central nervous system effect in the category of isoquinolines ... extracted, opium contains two main groups of alkaloids; the psychoactive constituents which are in the category …
Matched Categories: … Antitussive Agents ... Sensory System Agents ... Gastrointestinal Agents ... Respiratory System Agents ... Central Nervous System Agents …

Nomifensine

Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Description: … The approved application holder removed Merital capsules from the market on January 23, 1986. …
Matched Categories: … Antidepressive Agents ... Dopamine Agents ... Neurotransmitter Agents …

Benzylpenicillin

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered...
Approved
Vet approved
Matched Description: … The natural penicillins may also be used as first or second line agents against susceptible gram positive ... D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. ... Aminoglycosides may be added for synergy against group B streptococcus (*S. agalactiae*), *S. viridans …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Flupentixol

Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Description: … Flupentixol is an antipsychotic drug of the thioxanthene group. ... It is approved for use in Canada and other countries around the world, but not in the US. …
Matched Categories: … Antidepressive Agents ... Dopamine Agents ... Antipsychotic Agents ... Neurotoxic agents ... Serotonin Agents …

Rosuvastatin

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Categories: … Anticholesteremic Agents ... Hypolipidemic Agents ... Agents Causing Muscle Toxicity ... Lipid Modifying Agents ... Lipid Regulating Agents …
Matched Products: … ROSUVASTATINA TEVA GROUP ... Rosuvastatin Actavis Group 5 mg Filmtabletten ... Rosuvastatin Actavis Group 10 mg Filmtabletten …

Betaine

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Description: … Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. ... The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment ... of homocystinuria,[L43105,L43115] and the EMA has approved the use of Amversio (betaine anhydrous, oral …
Matched Categories: … Lipotropic Agents ... Gastrointestinal Agents ... Lipid Regulating Agents ... Other Miscellaneous Therapeutic Agents …

Vaborbactam

Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. It has been used in trials investigating the treatment of bacterial infections in subjects with varying degrees of renal insufficiency. In August 2017, a combination antibacterial therapy under the market name Vabomere was approved by the FDA for...
Approved
Investigational
Matched Description: … In August 2017, a combination antibacterial therapy under the market name Vabomere was approved by the …
Matched Categories: … Anti-Infective Agents …

Demeclocycline

A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Photosensitizing Agents ... Agents that produce neuromuscular block (indirect) …

Etanercept

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Categories: … Antirheumatic Agents ... Anti-Inflammatory Agents ... Agents reducing cytokine levels ... Immunosuppressive Agents ... Disease-modifying Antirheumatic Agents …
Matched Products: … Truemed Group LLC …

Molybdenum

Molybdenum is a chemical element with symbol Mo and atomic number 42. As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation states in minerals. Molybdenum is commonly used in metallurgy and other chemical applications however it has essential biological roles in...
Approved

Estradiol cypionate

Estradiol Cypionate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol cypionate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Mixtures name: … Truemed Group LLC …
Matched Categories: … Contraceptive Agents, Female ... Contraceptive Agents, Hormonal ... Reproductive Control Agents …

Doxacurium

Doxacurium chloride is a long-acting, nondepolarizing skeletal muscle relaxant for intravenous administration.
Approved
Matched Categories: … Anticholinergic Agents ... Neuromuscular Agents ... Neuromuscular Blocking Agents ... Peripheral Nervous System Agents ... Muscle Relaxants, Peripherally Acting Agents …

Carprofen

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Categories: … Nephrotoxic agents ... Antirheumatic Agents ... Agents causing hyperkalemia ... Anti-Inflammatory Agents ... Sensory System Agents …

Clocortolone

Clocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.
Approved
Matched Categories: … Corticosteroids, Moderately Potent (Group II) ... Anti-Inflammatory Agents ... Immunosuppressive Agents …

Crizanlizumab

Crizanlizumab is a humanized IgG2 monoclonal antibody used to reduce the frequency of vaso-occlusive crises in patients with sickle cell disease. Sickle cell disease is a genetically inherited condition prevalent in the Middle East, Africa, and certain parts of India. The genetic mutation associated with this disease leads to the...
Approved
Investigational

Ulobetasol

Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.
Approved
Matched Categories: … Corticosteroids, Potent (Group III) ... Cardiovascular Agents ... Anti-Inflammatory Agents ... Vasoconstrictor Agents ... Immunosuppressive Agents …

Rezafungin

Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Description: … [A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and …
Matched Categories: … Antifungal Agents ... Anti-Infective Agents ... Photosensitizing Agents …

Dinutuximab

Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Categories: … Antineoplastic Agents ... Hypotensive Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild ... It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors …
Matched Categories: … Hypotensive Agents ... Cardiovascular Agents ... Antihypertensive Agents ... Agents producing tachycardia ... Agents that produce hypertension …

Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Mixtures name: … Truemed Group LLC …
Matched Categories: … Antineoplastic Agents ... Contraceptive Agents, Male ... Antineoplastic Agents, Hormonal ... Contraceptive Agents, Female ... Contraceptive Agents, Hormonal …

Sutimlimab

Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Description: … [A245154] Notably, none of these agents are approved for use in the treatment of CAD. ... [A245159] Pharmacologic strategies have included the targeting of B-cells with agents like [rituximab ... [L40114,A245144] Sutimlimab was also approved by the European Commission in November 2022.[L44116] …
Matched Categories: … Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents …

Lomitapide

Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial hypercholesterolemia (HoFH) patients. It is marketed under the name Juxtapid (R).
Approved
Investigational
Matched Categories: … Hepatotoxic Agents ... Hypolipidemic Agents ... Lipid Modifying Agents ... Lipid Modifying Agents, Plain ... Hypolipidemic Agents Indicated for Hyperlipidemia …

Celiprolol

Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In 2010 a clinical trial has suggested a use for this medication in the prevention of...
Approved
Investigational
Matched Description: … Celiprolol is not approved for use by the FDA in the treatment of vascular Ehlers–Danlos syndrome. …
Matched Categories: … Adrenergic Agents ... Autonomic Agents ... Antiarrhythmic agents ... Vasodilating Agents ... Cardiovascular Agents …

Homatropine

Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions. Homatropine is included in subtherapeutic amounts as homatropine...
Approved
Matched Description: … accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic use has not been approved …
Matched Categories: … Autonomic Agents ... Anticholinergic Agents ... Peripheral Nervous System Agents …
Displaying drugs 26 - 50 of 8595 in total