Opium

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Opium
Accession Number
DB11130
Type
Small Molecule
Groups
Approved, Illicit
Description

The air-dried exudate from the unripe seed capsule of the opium poppy, Papaver somniferum, or its variant, P. album. It contains a number of alkaloids, but only a few - morphine; codeine; and papaverine - have clinical significance. Opium has been used as an analgesic, antitussive, antidiarrheal, and antispasmodic.

Structure
Thumb
Synonyms
  • Papaver somniferum exudate
  • Papaver somniferum resin
External IDs
IDS-NO-001
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Opium TeintureTincture200 gOralLaboratoire Atlas Inc1951-12-311996-09-09Canada
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Belladonna and OpiumOpium (30 mg/1) + Belladonna (16.2 mg/1)SuppositoryRectalPaddock Laboratories, Inc.1994-05-01Not applicableUs
Belladonna and OpiumOpium (60 mg/1) + Belladonna (16.2 mg/1)SuppositoryRectalPaddock Laboratories, Inc.1997-04-22Not applicableUs
Camphorated Opium TinctureOpium (5 ml) + Benzoic Acid (500 mg) + Camphor (300 mg)TinctureOralD.C. Labs Limited1951-12-312003-07-11Canada
Diban CapOpium (12 mg) + Atropine Sulfate (9.7 mcg) + Attapulgite (300 mg) + Hyoscyamine sulfate (0.0519 mg) + Pectin (71.4 mg) + Scopolamine (3.3 mcg)CapsuleOralAyerst Laboratories1992-12-311999-04-12Canada
Diban CapOpium (12 mg) + Atropine Sulfate (9.7 mcg) + Attapulgite (300 mg) + Hyoscyamine sulfate (0.0519 mg) + Pectin (71.4 mg) + Scopolamine (3.3 mcg)CapsuleOralWyeth Ayerst Canada Inc.1998-02-182001-01-30Canada
Donnagel-PG CapOpium (12 mg) + Attapulgite (300 mg) + Pectin (71.4 mg)CapsuleOralWyeth Ayerst Canada Inc.1994-12-312002-03-20Canada
Donnagel-PG LiqOpium (24 mg) + Kaolin (6 g) + Pectin (142.8 mg)LiquidOralWyeth Ayerst Canada Inc.1994-12-312001-04-23Canada
Opium and Belladonna SupOpium (65 mg) + Belladonna (15 mg)SuppositoryRectalSmithkline Beecham Pharma Division Of Smithkline Beecham Inc1993-12-311998-07-28Canada
Opium Camphre Tanin TabOpium (15 mg) + Camphor (60 mg) + Tannic acid (120 mg)TabletOralRougier Pharma Division Of Ratiopharm Inc1951-12-311999-09-27Canada
ParegoriqueOpium (50 ml) + Camphor (3 g)TinctureOralLaboratoire Atlas Inc1951-12-312006-06-14Canada
Categories
UNII
37M3MZ001L
CAS number
8008-60-4
Weight
Not Available
Chemical Formula
Not Available
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

Pharmacology

Indication
Not Available
Structured Indications
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
2,5-Dimethoxy-4-ethylamphetamine2,5-Dimethoxy-4-ethylamphetamine may increase the analgesic activities of Opium.Experimental, Illicit
3,4-Methylenedioxyamphetamine3,4-Methylenedioxyamphetamine may increase the analgesic activities of Opium.Experimental, Illicit
4-Bromo-2,5-dimethoxyamphetamine4-Bromo-2,5-dimethoxyamphetamine may increase the analgesic activities of Opium.Experimental, Illicit
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Opium.Experimental
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolineThe risk or severity of adverse effects can be increased when Opium is combined with 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline.Experimental
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Opium.Approved, Vet Approved
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Opium.Approved
AcetazolamideThe risk or severity of adverse effects can be increased when Opium is combined with Acetazolamide.Approved, Vet Approved
AclidiniumThe risk or severity of adverse effects can be increased when Aclidinium is combined with Opium.Approved
AdipiplonThe risk or severity of adverse effects can be increased when Adipiplon is combined with Opium.Investigational
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Opium.Approved, Investigational
AlaproclateOpium may increase the serotonergic activities of Alaproclate.Experimental
AlcuroniumThe risk or severity of adverse effects can be increased when Alcuronium is combined with Opium.Experimental
AlfaxaloneThe risk or severity of adverse effects can be increased when Opium is combined with Alfaxalone.Vet Approved
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Opium.Approved, Illicit
AlimemazineAlimemazine may increase the hypotensive activities of Opium.Approved, Vet Approved
AllopregnanoloneThe risk or severity of adverse effects can be increased when Opium is combined with Allopregnanolone.Investigational
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with Opium.Experimental, Illicit
AlphaprodineThe risk or severity of adverse effects can be increased when Opium is combined with Alphaprodine.Illicit
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Opium.Approved, Illicit, Investigational
AlvimopanThe risk or severity of adverse effects can be increased when Opium is combined with Alvimopan.Approved
AmilorideThe risk or severity of adverse effects can be increased when Opium is combined with Amiloride.Approved
AmisulprideThe risk or severity of adverse effects can be increased when Amisulpride is combined with Opium.Approved, Investigational
AmitriptylineThe risk or severity of adverse effects can be increased when Opium is combined with Amitriptyline.Approved
Ammonium chlorideAmmonium chloride may increase the excretion rate of Opium which could result in a lower serum level and potentially a reduction in efficacy.Approved, Vet Approved
AmobarbitalThe risk or severity of adverse effects can be increased when Amobarbital is combined with Opium.Approved, Illicit
AmoxapineThe risk or severity of adverse effects can be increased when Opium is combined with Amoxapine.Approved
AmperozideThe risk or severity of adverse effects can be increased when Amperozide is combined with Opium.Experimental
AmphetamineAmphetamine may increase the analgesic activities of Opium.Approved, Illicit
Anisotropine MethylbromideThe risk or severity of adverse effects can be increased when Anisotropine Methylbromide is combined with Opium.Approved
AripiprazoleThe risk or severity of adverse effects can be increased when Aripiprazole is combined with Opium.Approved, Investigational
ArticaineThe risk or severity of adverse effects can be increased when Articaine is combined with Opium.Approved
AsenapineThe risk or severity of adverse effects can be increased when Asenapine is combined with Opium.Approved
AtracuriumThe risk or severity of adverse effects can be increased when Atracurium is combined with Opium.Experimental
Atracurium besylateThe risk or severity of adverse effects can be increased when Atracurium besylate is combined with Opium.Approved
AtropineThe risk or severity of adverse effects can be increased when Atropine is combined with Opium.Approved, Vet Approved
AzaperoneThe risk or severity of adverse effects can be increased when Opium is combined with Azaperone.Vet Approved
AzelastineOpium may increase the central nervous system depressant (CNS depressant) activities of Azelastine.Approved
AzosemideThe risk or severity of adverse effects can be increased when Opium is combined with Azosemide.Investigational
BaclofenThe risk or severity of adverse effects can be increased when Opium is combined with Baclofen.Approved
BarbitalThe risk or severity of adverse effects can be increased when Barbital is combined with Opium.Illicit
BenactyzineThe risk or severity of adverse effects can be increased when Benactyzine is combined with Opium.Withdrawn
BendroflumethiazideThe risk or severity of adverse effects can be increased when Opium is combined with Bendroflumethiazide.Approved
BenmoxinThe risk or severity of adverse effects can be increased when Opium is combined with Benmoxin.Withdrawn
BenperidolThe risk or severity of adverse effects can be increased when Opium is combined with Benperidol.Investigational
BenzatropineThe risk or severity of adverse effects can be increased when Benzatropine is combined with Opium.Approved
BenzocaineThe risk or severity of adverse effects can be increased when Benzocaine is combined with Opium.Approved
BenzphetamineBenzphetamine may increase the analgesic activities of Opium.Approved, Illicit
Benzyl alcoholThe risk or severity of adverse effects can be increased when Benzyl alcohol is combined with Opium.Approved
BiperidenThe risk or severity of adverse effects can be increased when Biperiden is combined with Opium.Approved
BL-1020BL-1020 may increase the hypotensive activities of Opium.Investigational
BornaprineThe risk or severity of adverse effects can be increased when Bornaprine is combined with Opium.Experimental
BrexpiprazoleThe risk or severity of adverse effects can be increased when Opium is combined with Brexpiprazole.Approved
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved
BrofaromineThe risk or severity of adverse effects can be increased when Opium is combined with Brofaromine.Experimental
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with Opium.Approved, Illicit
BromisovalThe risk or severity of adverse effects can be increased when Opium is combined with Bromisoval.Experimental
BromperidolThe risk or severity of adverse effects can be increased when Opium is combined with Bromperidol.Investigational
BrompheniramineThe risk or severity of adverse effects can be increased when Opium is combined with Brompheniramine.Approved
BrotizolamThe risk or severity of adverse effects can be increased when Brotizolam is combined with Opium.Approved, Withdrawn
BumetanideThe risk or severity of adverse effects can be increased when Opium is combined with Bumetanide.Approved
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with Opium.Approved, Investigational
BuprenorphineOpium may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Opium.Approved, Investigational
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Opium.Approved, Illicit
ButacaineThe risk or severity of adverse effects can be increased when Opium is combined with Butacaine.Vet Approved
ButalbitalThe risk or severity of adverse effects can be increased when Opium is combined with Butalbital.Approved, Illicit
ButambenThe risk or severity of adverse effects can be increased when Opium is combined with Butamben.Approved
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with Opium.Approved, Illicit
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Opium.Approved, Illicit, Vet Approved
CanertinibThe risk or severity of adverse effects can be increased when Canertinib is combined with Opium.Investigational
Canrenoic acidThe risk or severity of adverse effects can be increased when Opium is combined with Canrenoic acid.Approved, Withdrawn
CanrenoneThe risk or severity of adverse effects can be increased when Opium is combined with Canrenone.Investigational
CarbamazepineThe risk or severity of adverse effects can be increased when Carbamazepine is combined with Opium.Approved, Investigational
CarbinoxamineThe risk or severity of adverse effects can be increased when Opium is combined with Carbinoxamine.Approved
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with Opium.Illicit, Vet Approved
CarisoprodolThe risk or severity of adverse effects can be increased when Opium is combined with Carisoprodol.Approved
CaroxazoneThe risk or severity of adverse effects can be increased when Opium is combined with Caroxazone.Withdrawn
CetirizineThe risk or severity of adverse effects can be increased when Opium is combined with Cetirizine.Approved
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with Opium.Approved, Illicit, Vet Approved
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Opium.Approved, Illicit
ChlormezanoneThe risk or severity of adverse effects can be increased when Chlormezanone is combined with Opium.Approved, Withdrawn
ChloroprocaineThe risk or severity of adverse effects can be increased when Chloroprocaine is combined with Opium.Approved
ChlorothiazideThe risk or severity of adverse effects can be increased when Opium is combined with Chlorothiazide.Approved, Vet Approved
ChlorphenamineThe risk or severity of adverse effects can be increased when Opium is combined with Chlorphenamine.Approved
ChlorphenoxamineThe risk or severity of adverse effects can be increased when Chlorphenoxamine is combined with Opium.Withdrawn
ChlorphentermineChlorphentermine may increase the analgesic activities of Opium.Illicit, Withdrawn
ChlorproethazineChlorproethazine may increase the hypotensive activities of Opium.Experimental
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with Opium.Approved, Vet Approved
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with Opium.Approved, Withdrawn
ChlorthalidoneThe risk or severity of adverse effects can be increased when Opium is combined with Chlorthalidone.Approved
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Opium is combined with Chlorzoxazone.Approved
CicletanineThe risk or severity of adverse effects can be increased when Opium is combined with Cicletanine.Investigational
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Opium.Approved, Vet Approved
CitalopramOpium may increase the serotonergic activities of Citalopram.Approved
ClemastineThe risk or severity of adverse effects can be increased when Opium is combined with Clemastine.Approved
ClidiniumThe risk or severity of adverse effects can be increased when Opium is combined with Clidinium.Approved
ClobazamThe risk or severity of adverse effects can be increased when Opium is combined with Clobazam.Approved, Illicit
ClofenamideThe risk or severity of adverse effects can be increased when Opium is combined with Clofenamide.Experimental
clomethiazoleThe risk or severity of adverse effects can be increased when clomethiazole is combined with Opium.Investigational
ClomipramineThe risk or severity of adverse effects can be increased when Opium is combined with Clomipramine.Approved, Vet Approved
ClonazepamThe risk or severity of adverse effects can be increased when Opium is combined with Clonazepam.Approved, Illicit
ClonidineThe risk or severity of adverse effects can be increased when Opium is combined with Clonidine.Approved
ClopamideThe risk or severity of adverse effects can be increased when Opium is combined with Clopamide.Experimental
ClopenthixolThe risk or severity of adverse effects can be increased when Opium is combined with Clopenthixol.Experimental
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Opium.Approved, Illicit
ClorexoloneThe risk or severity of adverse effects can be increased when Opium is combined with Clorexolone.Experimental
ClothiapineThe risk or severity of adverse effects can be increased when Opium is combined with Clothiapine.Experimental
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with Opium.Approved
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with Opium.Approved, Illicit
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with Opium.Approved, Illicit
ConivaptanThe risk or severity of adverse effects can be increased when Opium is combined with Conivaptan.Approved, Investigational
CyclizineThe risk or severity of adverse effects can be increased when Opium is combined with Cyclizine.Approved
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Opium.Approved
CyclopenthiazideThe risk or severity of adverse effects can be increased when Opium is combined with Cyclopenthiazide.Experimental
CyclopentolateThe risk or severity of adverse effects can be increased when Cyclopentolate is combined with Opium.Approved
CyclothiazideThe risk or severity of adverse effects can be increased when Opium is combined with Cyclothiazide.Approved
CyproheptadineThe risk or severity of adverse effects can be increased when Opium is combined with Cyproheptadine.Approved
DantroleneThe risk or severity of adverse effects can be increased when Opium is combined with Dantrolene.Approved
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Opium.Approved
DapoxetineOpium may increase the serotonergic activities of Dapoxetine.Investigational
DarifenacinThe risk or severity of adverse effects can be increased when Darifenacin is combined with Opium.Approved, Investigational
DeramciclaneThe risk or severity of adverse effects can be increased when Deramciclane is combined with Opium.Investigational
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with Opium.Approved
DesipramineThe risk or severity of adverse effects can be increased when Opium is combined with Desipramine.Approved
DesloratadineThe risk or severity of adverse effects can be increased when Opium is combined with Desloratadine.Approved, Investigational
DesmopressinThe risk or severity of adverse effects can be increased when Opium is combined with Desmopressin.Approved
DesvenlafaxineOpium may increase the serotonergic activities of Desvenlafaxine.Approved
DetomidineThe risk or severity of adverse effects can be increased when Opium is combined with Detomidine.Vet Approved
DexbrompheniramineThe risk or severity of adverse effects can be increased when Opium is combined with Dexbrompheniramine.Approved
DexetimideThe risk or severity of adverse effects can be increased when Dexetimide is combined with Opium.Withdrawn
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Opium.Approved, Vet Approved
DextroamphetamineDextroamphetamine may increase the analgesic activities of Opium.Approved, Illicit
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with Opium.Experimental, Illicit
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Opium.Approved, Illicit, Withdrawn
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with Opium.Approved
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Opium.Approved, Illicit, Vet Approved
DicyclomineThe risk or severity of adverse effects can be increased when Dicyclomine is combined with Opium.Approved
Diethyl etherThe risk or severity of adverse effects can be increased when Opium is combined with Diethyl ether.Experimental
DiethylpropionDiethylpropion may increase the analgesic activities of Opium.Approved, Illicit
DifenoxinThe risk or severity of adverse effects can be increased when Opium is combined with Difenoxin.Approved, Illicit
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Opium.Approved, Illicit
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Opium.Experimental, Illicit
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with Opium.Experimental, Illicit
DimenhydrinateThe risk or severity of adverse effects can be increased when Opium is combined with Dimenhydrinate.Approved
DiphenhydramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Opium.Approved
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with Opium.Approved, Illicit
DixyrazineThe risk or severity of adverse effects can be increased when Opium is combined with Dixyrazine.Experimental
DoramectinThe risk or severity of adverse effects can be increased when Opium is combined with Doramectin.Vet Approved
DoxepinThe risk or severity of adverse effects can be increased when Opium is combined with Doxepin.Approved
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved, Vet Approved
DPDPEThe risk or severity of adverse effects can be increased when DPDPE is combined with Opium.Investigational
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved, Illicit
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved, Vet Approved
DrospirenoneThe risk or severity of adverse effects can be increased when Opium is combined with Drospirenone.Approved
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with Opium.Experimental, Illicit
DuloxetineOpium may increase the serotonergic activities of Duloxetine.Approved
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Opium.Approved
EcgonineThe risk or severity of adverse effects can be increased when Ecgonine is combined with Opium.Experimental, Illicit
EcopipamThe risk or severity of adverse effects can be increased when Opium is combined with Ecopipam.Investigational
EfavirenzThe risk or severity of adverse effects can be increased when Opium is combined with Efavirenz.Approved, Investigational
EfonidipineThe risk or severity of adverse effects can be increased when Opium is combined with Efonidipine.Approved
EltanoloneThe risk or severity of adverse effects can be increased when Opium is combined with Eltanolone.Investigational
EluxadolineOpium may increase the constipating activities of Eluxadoline.Approved
EmeproniumThe risk or severity of adverse effects can be increased when Emepronium is combined with Opium.Experimental
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Opium.Approved, Vet Approved
EntacaponeThe risk or severity of adverse effects can be increased when Opium is combined with Entacapone.Approved, Investigational
EplerenoneThe risk or severity of adverse effects can be increased when Opium is combined with Eplerenone.Approved
EscitalopramOpium may increase the serotonergic activities of Escitalopram.Approved, Investigational
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with Opium.Approved, Illicit
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Opium.Approved
Etacrynic acidThe risk or severity of adverse effects can be increased when Opium is combined with Etacrynic acid.Approved
EtanautineThe risk or severity of adverse effects can be increased when Etanautine is combined with Opium.Experimental
EthanolOpium may increase the central nervous system depressant (CNS depressant) activities of Ethanol.Approved
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Opium.Approved, Illicit, Withdrawn
EthopropazineThe risk or severity of adverse effects can be increased when Ethopropazine is combined with Opium.Approved
EthosuximideThe risk or severity of adverse effects can be increased when Opium is combined with Ethosuximide.Approved
EthotoinThe risk or severity of adverse effects can be increased when Opium is combined with Ethotoin.Approved
EthoxzolamideThe risk or severity of adverse effects can be increased when Opium is combined with Ethoxzolamide.Withdrawn
Ethyl carbamateThe risk or severity of adverse effects can be increased when Ethyl carbamate is combined with Opium.Withdrawn
Ethyl chlorideThe risk or severity of adverse effects can be increased when Opium is combined with Ethyl chloride.Experimental
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with Opium.Approved, Illicit
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with Opium.Approved, Illicit
EtidocaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Opium.Approved
EtifoxineThe risk or severity of adverse effects can be increased when Etifoxine is combined with Opium.Withdrawn
EtizolamThe risk or severity of adverse effects can be increased when Etizolam is combined with Opium.Approved
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Opium.Approved
EtoperidoneOpium may increase the serotonergic activities of Etoperidone.Approved
EtorphineThe risk or severity of adverse effects can be increased when Etorphine is combined with Opium.Illicit, Vet Approved
EtybenzatropineThe risk or severity of adverse effects can be increased when Etybenzatropine is combined with Opium.Experimental
EzogabineThe risk or severity of adverse effects can be increased when Opium is combined with Ezogabine.Approved
FelbamateThe risk or severity of adverse effects can be increased when Opium is combined with Felbamate.Approved
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with Opium.Approved, Illicit, Withdrawn
FenquizoneThe risk or severity of adverse effects can be increased when Opium is combined with Fenquizone.Experimental
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Opium.Approved, Illicit, Investigational, Vet Approved
FesoterodineThe risk or severity of adverse effects can be increased when Fesoterodine is combined with Opium.Approved
FexofenadineThe risk or severity of adverse effects can be increased when Opium is combined with Fexofenadine.Approved
FlibanserinThe risk or severity of adverse effects can be increased when Opium is combined with Flibanserin.Approved
FluanisoneThe risk or severity of adverse effects can be increased when Opium is combined with Fluanisone.Experimental
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with Opium.Approved, Illicit
FlunarizineThe risk or severity of adverse effects can be increased when Opium is combined with Flunarizine.Approved
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with Opium.Approved, Illicit
FluoxetineOpium may increase the serotonergic activities of Fluoxetine.Approved, Vet Approved
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with Opium.Approved, Withdrawn
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Opium.Approved
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Opium.Approved, Illicit
FluspirileneThe risk or severity of adverse effects can be increased when Fluspirilene is combined with Opium.Approved
Fluticasone propionateThe risk or severity of adverse effects can be increased when Opium is combined with Fluticasone propionate.Approved
FluvoxamineThe risk or severity of adverse effects can be increased when Fluvoxamine is combined with Opium.Approved, Investigational
FosphenytoinThe risk or severity of adverse effects can be increased when Opium is combined with Fosphenytoin.Approved
FospropofolThe risk or severity of adverse effects can be increased when Fospropofol is combined with Opium.Approved, Illicit
FurazolidoneThe risk or severity of adverse effects can be increased when Opium is combined with Furazolidone.Approved, Vet Approved
FurosemideThe risk or severity of adverse effects can be increased when Opium is combined with Furosemide.Approved, Vet Approved
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Opium.Approved, Investigational
Gabapentin EnacarbilThe risk or severity of adverse effects can be increased when Opium is combined with Gabapentin Enacarbil.Approved
GallamineThe risk or severity of adverse effects can be increased when Gallamine is combined with Opium.Experimental
Gallamine TriethiodideThe risk or severity of adverse effects can be increased when Gallamine Triethiodide is combined with Opium.Approved
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Opium.Approved, Illicit
GepefrineGepefrine may increase the analgesic activities of Opium.Experimental
GepironeThe risk or severity of adverse effects can be increased when Opium is combined with Gepirone.Investigational
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with Opium.Approved, Illicit
GlycopyrroniumThe risk or severity of adverse effects can be increased when Glycopyrronium is combined with Opium.Approved, Investigational, Vet Approved
GuanfacineThe risk or severity of adverse effects can be increased when Opium is combined with Guanfacine.Approved, Investigational
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Opium.Approved, Illicit, Withdrawn
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Opium.Approved
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with Opium.Approved, Vet Approved
HarmalineThe risk or severity of adverse effects can be increased when Opium is combined with Harmaline.Experimental
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with Opium.Approved, Illicit
HexamethoniumThe risk or severity of adverse effects can be increased when Hexamethonium is combined with Opium.Experimental
HexobarbitalThe risk or severity of adverse effects can be increased when Hexobarbital is combined with Opium.Approved
HomatropineThe risk or severity of adverse effects can be increased when Homatropine is combined with Opium.Approved
HydracarbazineThe risk or severity of adverse effects can be increased when Opium is combined with Hydracarbazine.Experimental
HydrochlorothiazideThe risk or severity of adverse effects can be increased when Opium is combined with Hydrochlorothiazide.Approved, Vet Approved
HydrocodoneOpium may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.Approved, Illicit
HydroflumethiazideThe risk or severity of adverse effects can be increased when Opium is combined with Hydroflumethiazide.Approved
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Opium.Approved, Illicit
HydroxyamphetamineHydroxyamphetamine may increase the analgesic activities of Opium.Approved
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved
HyoscyamineThe risk or severity of adverse effects can be increased when Hyoscyamine is combined with Opium.Approved
IbopamineThe risk or severity of adverse effects can be increased when Opium is combined with Ibopamine.Experimental
IloperidoneThe risk or severity of adverse effects can be increased when Opium is combined with Iloperidone.Approved
ImipramineThe risk or severity of adverse effects can be increased when Opium is combined with Imipramine.Approved
IndalpineOpium may increase the serotonergic activities of Indalpine.Investigational, Withdrawn
IndapamideThe risk or severity of adverse effects can be increased when Opium is combined with Indapamide.Approved
IndiplonThe risk or severity of adverse effects can be increased when Opium is combined with Indiplon.Investigational
Iofetamine I-123Iofetamine I-123 may increase the analgesic activities of Opium.Approved
Ipratropium bromideThe risk or severity of adverse effects can be increased when Ipratropium bromide is combined with Opium.Approved
IproclozideThe risk or severity of adverse effects can be increased when Opium is combined with Iproclozide.Withdrawn
IproniazidThe risk or severity of adverse effects can be increased when Opium is combined with Iproniazid.Withdrawn
IsocarboxazidThe risk or severity of adverse effects can be increased when Opium is combined with Isocarboxazid.Approved
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Opium.Approved, Vet Approved
IsosorbideThe risk or severity of adverse effects can be increased when Opium is combined with Isosorbide.Approved
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with Opium.Approved, Vet Approved
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with Opium.Approved
KetobemidoneThe risk or severity of adverse effects can be increased when Ketobemidone is combined with Opium.Approved
LamotrigineThe risk or severity of adverse effects can be increased when Opium is combined with Lamotrigine.Approved, Investigational
LevetiracetamThe risk or severity of adverse effects can be increased when Opium is combined with Levetiracetam.Approved, Investigational
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with Opium.Approved
LevocabastineThe risk or severity of adverse effects can be increased when Opium is combined with Levocabastine.Approved
LevocetirizineThe risk or severity of adverse effects can be increased when Opium is combined with Levocetirizine.Approved
LevodopaThe risk or severity of adverse effects can be increased when Opium is combined with Levodopa.Approved
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Opium.Approved
LevomilnacipranOpium may increase the serotonergic activities of Levomilnacipran.Approved
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Opium.Approved
LidocaineThe risk or severity of adverse effects can be increased when Lidocaine is combined with Opium.Approved, Vet Approved
LisdexamfetamineLisdexamfetamine may increase the analgesic activities of Opium.Approved, Investigational
LithiumThe risk or severity of adverse effects can be increased when Lithium is combined with Opium.Approved
LofentanilThe risk or severity of adverse effects can be increased when Lofentanil is combined with Opium.Illicit
LoprazolamThe risk or severity of adverse effects can be increased when Opium is combined with Loprazolam.Experimental
LoratadineThe risk or severity of adverse effects can be increased when Opium is combined with Loratadine.Approved
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Opium.Approved
LormetazepamThe risk or severity of adverse effects can be increased when Opium is combined with Lormetazepam.Approved
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Opium.Approved
LurasidoneThe risk or severity of adverse effects can be increased when Lurasidone is combined with Opium.Approved
Magnesium SulfateMagnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved, Vet Approved
MannitolThe risk or severity of adverse effects can be increased when Opium is combined with Mannitol.Approved, Investigational
MaprotilineThe risk or severity of adverse effects can be increased when Opium is combined with Maprotiline.Approved
MazaticolThe risk or severity of adverse effects can be increased when Mazaticol is combined with Opium.Experimental
MebanazineThe risk or severity of adverse effects can be increased when Opium is combined with Mebanazine.Withdrawn
MebicarThe risk or severity of adverse effects can be increased when Opium is combined with Mebicar.Experimental
MebutizideThe risk or severity of adverse effects can be increased when Opium is combined with Mebutizide.Experimental
MecamylamineThe risk or severity of adverse effects can be increased when Mecamylamine is combined with Opium.Approved
MeclizineThe risk or severity of adverse effects can be increased when Opium is combined with Meclizine.Approved
MedazepamThe risk or severity of adverse effects can be increased when Opium is combined with Medazepam.Experimental
MedetomidineThe risk or severity of adverse effects can be increased when Opium is combined with Medetomidine.Vet Approved
MefrusideThe risk or severity of adverse effects can be increased when Opium is combined with Mefruside.Experimental
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Opium.Approved, Nutraceutical, Vet Approved
MelperoneThe risk or severity of adverse effects can be increased when Melperone is combined with Opium.Approved
MephedroneMephedrone may increase the analgesic activities of Opium.Investigational
MephentermineMephentermine may increase the analgesic activities of Opium.Approved
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Opium.Approved, Vet Approved
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Opium.Approved, Illicit
MeptazinolThe risk or severity of adverse effects can be increased when Opium is combined with Meptazinol.Experimental
MersalylThe risk or severity of adverse effects can be increased when Opium is combined with Mersalyl.Approved
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Opium.Approved
MetaxaloneThe risk or severity of adverse effects can be increased when Opium is combined with Metaxalone.Approved
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Opium.Approved
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with Opium.Approved, Illicit
MethamphetamineMethamphetamine may increase the analgesic activities of Opium.Approved, Illicit
MethanthelineThe risk or severity of adverse effects can be increased when Methantheline is combined with Opium.Approved
MethapyrileneThe risk or severity of adverse effects can be increased when Methapyrilene is combined with Opium.Withdrawn
MethaqualoneThe risk or severity of adverse effects can be increased when Methaqualone is combined with Opium.Illicit, Withdrawn
MethazolamideThe risk or severity of adverse effects can be increased when Opium is combined with Methazolamide.Approved
MethocarbamolThe risk or severity of adverse effects can be increased when Opium is combined with Methocarbamol.Approved, Vet Approved
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with Opium.Approved
MethotrimeprazineOpium may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.Approved
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with Opium.Approved, Vet Approved
MethoxyphenamineMethoxyphenamine may increase the analgesic activities of Opium.Experimental
MethsuximideThe risk or severity of adverse effects can be increased when Opium is combined with Methsuximide.Approved
MethyclothiazideThe risk or severity of adverse effects can be increased when Opium is combined with Methyclothiazide.Approved
MethylecgonineThe risk or severity of adverse effects can be increased when Methylecgonine is combined with Opium.Experimental
Methylene blueMethylene blue may increase the hypotensive activities of Opium.Investigational
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Opium.Approved
MeticraneThe risk or severity of adverse effects can be increased when Opium is combined with Meticrane.Experimental
MetixeneThe risk or severity of adverse effects can be increased when Metixene is combined with Opium.Approved
MetolazoneThe risk or severity of adverse effects can be increased when Opium is combined with Metolazone.Approved
MetyrosineOpium may increase the sedative activities of Metyrosine.Approved
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Opium.Approved, Illicit
Midomafetamine3,4-Methylenedioxymethamphetamine may increase the analgesic activities of Opium.Experimental, Illicit
MilnacipranOpium may increase the serotonergic activities of Milnacipran.Approved
MinaprineThe risk or severity of adverse effects can be increased when Opium is combined with Minaprine.Approved
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved, Investigational
MirtazapineOpium may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.Approved
MMDAMMDA may increase the analgesic activities of Opium.Experimental, Illicit
MoclobemideThe risk or severity of adverse effects can be increased when Opium is combined with Moclobemide.Approved
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with Opium.Approved
MoricizineMoricizine may increase the hypotensive activities of Opium.Approved, Withdrawn
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Opium.Approved, Investigational
MuzolimineThe risk or severity of adverse effects can be increased when Opium is combined with Muzolimine.Experimental
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved, Investigational
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Opium.Approved
NaltrexoneThe therapeutic efficacy of Opium can be decreased when used in combination with Naltrexone.Approved, Investigational, Vet Approved
NefazodoneOpium may increase the serotonergic activities of Nefazodone.Approved, Withdrawn
NialamideThe risk or severity of adverse effects can be increased when Opium is combined with Nialamide.Withdrawn
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with Opium.Approved
Nitrous oxideThe risk or severity of adverse effects can be increased when Nitrous oxide is combined with Opium.Approved, Vet Approved
NorfluraneThe risk or severity of adverse effects can be increased when Opium is combined with Norflurane.Investigational
NormethadoneThe risk or severity of adverse effects can be increased when Opium is combined with Normethadone.Approved, Illicit
NortriptylineThe risk or severity of adverse effects can be increased when Opium is combined with Nortriptyline.Approved
OctamoxinThe risk or severity of adverse effects can be increased when Opium is combined with Octamoxin.Withdrawn
OlanzapineThe risk or severity of adverse effects can be increased when Olanzapine is combined with Opium.Approved, Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Opium is combined with Olopatadine.Approved
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with Opium.Approved
OrphenadrineOpium may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.Approved
OsanetantThe risk or severity of adverse effects can be increased when Osanetant is combined with Opium.Investigational
OtiloniumThe risk or severity of adverse effects can be increased when Otilonium is combined with Opium.Experimental
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Opium.Approved
OxethazaineThe risk or severity of adverse effects can be increased when Opium is combined with Oxethazaine.Investigational
OxitropiumThe risk or severity of adverse effects can be increased when Oxitropium is combined with Opium.Investigational
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with Opium.Approved
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Opium.Approved
OxybutyninThe risk or severity of adverse effects can be increased when Oxybutynin is combined with Opium.Approved, Investigational
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with Opium.Approved, Illicit, Investigational
OxymorphoneThe risk or severity of adverse effects can be increased when Oxymorphone is combined with Opium.Approved, Investigational, Vet Approved
OxyphenoniumThe risk or severity of adverse effects can be increased when Oxyphenonium is combined with Opium.Approved
PaliperidoneThe risk or severity of adverse effects can be increased when Paliperidone is combined with Opium.Approved
PancuroniumThe risk or severity of adverse effects can be increased when Pancuronium is combined with Opium.Approved
ParaldehydeOpium may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.Approved
PargylineThe risk or severity of adverse effects can be increased when Opium is combined with Pargyline.Approved
ParoxetineOpium may increase the serotonergic activities of Paroxetine.Approved, Investigational
PegvisomantThe therapeutic efficacy of Pegvisomant can be decreased when used in combination with Opium.Approved
PenfluridolThe risk or severity of adverse effects can be increased when Opium is combined with Penfluridol.Experimental
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Opium.Approved, Vet Approved
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with Opium.Approved, Vet Approved
PentoliniumThe risk or severity of adverse effects can be increased when Pentolinium is combined with Opium.Approved
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved
PerazineThe risk or severity of adverse effects can be increased when Opium is combined with Perazine.Investigational
PerospironeThe risk or severity of adverse effects can be increased when Perospirone is combined with Opium.Approved
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Opium.Approved
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Opium.Approved
PhenazocineThe risk or severity of adverse effects can be increased when Opium is combined with Phenazocine.Experimental
PhenelzineThe risk or severity of adverse effects can be increased when Opium is combined with Phenelzine.Approved
PhenglutarimideThe risk or severity of adverse effects can be increased when Phenglutarimide is combined with Opium.Experimental
PhenibutThe risk or severity of adverse effects can be increased when Opium is combined with Phenibut.Experimental
PheniprazineThe risk or severity of adverse effects can be increased when Opium is combined with Pheniprazine.Withdrawn
PhenobarbitalThe risk or severity of adverse effects can be increased when Phenobarbital is combined with Opium.Approved
PhenoperidineThe risk or severity of adverse effects can be increased when Opium is combined with Phenoperidine.Experimental
PhenoxyethanolThe risk or severity of adverse effects can be increased when Opium is combined with Phenoxyethanol.Approved
PhenoxypropazineThe risk or severity of adverse effects can be increased when Opium is combined with Phenoxypropazine.Withdrawn
PhenterminePhentermine may increase the analgesic activities of Opium.Approved, Illicit
PhenytoinThe risk or severity of adverse effects can be increased when Opium is combined with Phenytoin.Approved, Vet Approved
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with Opium.Approved
PipamperoneThe risk or severity of adverse effects can be increased when Pipamperone is combined with Opium.Approved
PipecuroniumThe risk or severity of adverse effects can be increased when Pipecuronium is combined with Opium.Approved
PipotiazineThe risk or severity of adverse effects can be increased when Opium is combined with Pipotiazine.Approved
PirenzepineThe risk or severity of adverse effects can be increased when Pirenzepine is combined with Opium.Approved
PiretanideThe risk or severity of adverse effects can be increased when Opium is combined with Piretanide.Experimental
PiritramideThe risk or severity of adverse effects can be increased when Opium is combined with Piritramide.Investigational
PirlindoleThe risk or severity of adverse effects can be increased when Opium is combined with Pirlindole.Approved
PivhydrazineThe risk or severity of adverse effects can be increased when Opium is combined with Pivhydrazine.Withdrawn
PizotifenThe risk or severity of adverse effects can be increased when Opium is combined with Pizotifen.Approved
PolythiazideThe risk or severity of adverse effects can be increased when Opium is combined with Polythiazide.Approved
PomalidomideThe risk or severity of adverse effects can be increased when Opium is combined with Pomalidomide.Approved
PotassiumThe risk or severity of adverse effects can be increased when Opium is combined with Potassium.Approved
Potassium CitrateThe risk or severity of adverse effects can be increased when Opium is combined with Potassium Citrate.Approved, Vet Approved
PramipexoleOpium may increase the sedative activities of Pramipexole.Approved, Investigational
PramocaineThe risk or severity of adverse effects can be increased when Pramocaine is combined with Opium.Approved
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with Opium.Approved, Illicit
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with Opium.Approved, Illicit, Investigational
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Opium.Approved
PrimidoneThe risk or severity of adverse effects can be increased when Opium is combined with Primidone.Approved, Vet Approved
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Opium.Approved, Investigational, Vet Approved
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with Opium.Approved, Vet Approved
ProcyclidineThe risk or severity of adverse effects can be increased when Procyclidine is combined with Opium.Approved
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with Opium.Approved, Vet Approved
PromethazineThe risk or severity of adverse effects can be increased when Opium is combined with Promethazine.Approved
PropanididThe risk or severity of adverse effects can be increased when Opium is combined with Propanidid.Experimental
PropanthelineThe risk or severity of adverse effects can be increased when Propantheline is combined with Opium.Approved
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Opium.Approved, Vet Approved
PropiopromazinePropiopromazine may increase the hypotensive activities of Opium.Vet Approved
PropiverineThe risk or severity of adverse effects can be increased when Propiverine is combined with Opium.Investigational
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Opium.Approved, Investigational, Vet Approved
PropoxycaineThe risk or severity of adverse effects can be increased when Propoxycaine is combined with Opium.Approved
ProtriptylineThe risk or severity of adverse effects can be increased when Opium is combined with Protriptyline.Approved
ProxibarbalThe risk or severity of adverse effects can be increased when Opium is combined with Proxibarbal.Experimental
PSD502The risk or severity of adverse effects can be increased when PSD502 is combined with Opium.Investigational
PseudoephedrinePseudoephedrine may increase the analgesic activities of Opium.Approved
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with Opium.Approved, Illicit
QuetiapineThe risk or severity of adverse effects can be increased when Quetiapine is combined with Opium.Approved
QuinethazoneThe risk or severity of adverse effects can be increased when Opium is combined with Quinethazone.Approved
QuinidineThe risk or severity of adverse effects can be increased when Quinidine is combined with Opium.Approved
QuinisocaineThe risk or severity of adverse effects can be increased when Opium is combined with Quinisocaine.Experimental
RacloprideThe risk or severity of adverse effects can be increased when Opium is combined with Raclopride.Investigational
RamelteonThe risk or severity of adverse effects can be increased when Opium is combined with Ramelteon.Approved, Investigational
RamosetronOpium may increase the constipating activities of Ramosetron.Approved
RasagilineThe risk or severity of adverse effects can be increased when Opium is combined with Rasagiline.Approved
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Opium.Approved
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Opium.Approved, Withdrawn
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Opium.Approved
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with Opium.Approved, Investigational
RitanserinThe risk or severity of adverse effects can be increased when Opium is combined with Ritanserin.Investigational
RitobegronRitobegron may increase the analgesic activities of Opium.Investigational
RolofyllineThe risk or severity of adverse effects can be increased when Opium is combined with Rolofylline.Investigational
RomifidineThe risk or severity of adverse effects can be increased when Opium is combined with Romifidine.Vet Approved
RopiniroleOpium may increase the sedative activities of Ropinirole.Approved, Investigational
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with Opium.Approved
RotigotineOpium may increase the sedative activities of Rotigotine.Approved
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Opium.Approved
SafrazineThe risk or severity of adverse effects can be increased when Opium is combined with Safrazine.Withdrawn
ScopolamineThe risk or severity of adverse effects can be increased when Opium is combined with Scopolamine.Approved
Scopolamine butylbromideThe risk or severity of adverse effects can be increased when Scopolamine butylbromide is combined with Opium.Approved, Vet Approved
SecobarbitalThe risk or severity of adverse effects can be increased when Secobarbital is combined with Opium.Approved, Vet Approved
SelegilineThe risk or severity of adverse effects can be increased when Opium is combined with Selegiline.Approved, Investigational, Vet Approved
SepranoloneThe risk or severity of adverse effects can be increased when Opium is combined with Sepranolone.Investigational
SertindoleThe risk or severity of adverse effects can be increased when Sertindole is combined with Opium.Approved, Withdrawn
SertralineOpium may increase the serotonergic activities of Sertraline.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Opium.Approved, Vet Approved
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved
SolifenacinThe risk or severity of adverse effects can be increased when Solifenacin is combined with Opium.Approved
SpiradolineThe risk or severity of adverse effects can be increased when Opium is combined with Spiradoline.Investigational
SpironolactoneThe risk or severity of adverse effects can be increased when Opium is combined with Spironolactone.Approved
StiripentolThe risk or severity of adverse effects can be increased when Opium is combined with Stiripentol.Approved
SuccinylcholineSuccinylcholine may increase the bradycardic activities of Opium.Approved
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Opium.Approved, Investigational
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Opium.Approved
SultoprideThe risk or severity of adverse effects can be increased when Opium is combined with Sultopride.Experimental
SuvorexantOpium may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.Approved
TandospironeThe risk or severity of adverse effects can be increased when Opium is combined with Tandospirone.Investigational
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Opium.Approved
TasimelteonThe risk or severity of adverse effects can be increased when Opium is combined with Tasimelteon.Approved
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Opium.Approved
TetrabenazineThe risk or severity of adverse effects can be increased when Opium is combined with Tetrabenazine.Approved
TetracaineThe risk or severity of adverse effects can be increased when Tetracaine is combined with Opium.Approved, Vet Approved
TetrahydropalmatineThe risk or severity of adverse effects can be increased when Opium is combined with Tetrahydropalmatine.Investigational
TetrodotoxinThe risk or severity of adverse effects can be increased when Tetrodotoxin is combined with Opium.Investigational
ThalidomideOpium may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.Approved, Investigational, Withdrawn
TheobromineThe risk or severity of adverse effects can be increased when Opium is combined with Theobromine.Approved
ThiamylalThe risk or severity of adverse effects can be increased when Thiamylal is combined with Opium.Approved, Vet Approved
ThiazinamThiazinam may increase the hypotensive activities of Opium.Experimental
ThiethylperazineThiethylperazine may increase the hypotensive activities of Opium.Withdrawn
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with Opium.Approved, Vet Approved
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with Opium.Withdrawn
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with Opium.Approved
TiagabineThe risk or severity of adverse effects can be increased when Opium is combined with Tiagabine.Approved
TiaprideThe risk or severity of adverse effects can be increased when Opium is combined with Tiapride.Approved, Investigational
TicrynafenThe risk or severity of adverse effects can be increased when Opium is combined with Ticrynafen.Withdrawn
TiletamineThe risk or severity of adverse effects can be increased when Opium is combined with Tiletamine.Vet Approved
TilidineThe risk or severity of adverse effects can be increased when Opium is combined with Tilidine.Experimental
TiotropiumThe risk or severity of adverse effects can be increased when Tiotropium is combined with Opium.Approved
TizanidineThe risk or severity of adverse effects can be increased when Opium is combined with Tizanidine.Approved
TolcaponeThe risk or severity of adverse effects can be increased when Opium is combined with Tolcapone.Approved, Withdrawn
ToloxatoneThe risk or severity of adverse effects can be increased when Opium is combined with Toloxatone.Approved
TolterodineThe risk or severity of adverse effects can be increased when Tolterodine is combined with Opium.Approved, Investigational
TolvaptanThe risk or severity of adverse effects can be increased when Opium is combined with Tolvaptan.Approved
TopiramateThe risk or severity of adverse effects can be increased when Opium is combined with Topiramate.Approved
TorasemideThe risk or severity of adverse effects can be increased when Opium is combined with Torasemide.Approved
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Opium.Approved, Investigational
Trans-2-PhenylcyclopropylamineThe risk or severity of adverse effects can be increased when Trans-2-Phenylcyclopropylamine is combined with Opium.Experimental
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with Opium.Approved
TrazodoneThe risk or severity of adverse effects can be increased when Trazodone is combined with Opium.Approved, Investigational
TriamtereneThe risk or severity of adverse effects can be increased when Opium is combined with Triamterene.Approved
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Opium.Approved
Tricaine methanesulfonateThe risk or severity of adverse effects can be increased when Opium is combined with Tricaine methanesulfonate.Vet Approved
TrichlormethiazideThe risk or severity of adverse effects can be increased when Opium is combined with Trichlormethiazide.Approved, Vet Approved
TrichloroethyleneThe risk or severity of adverse effects can be increased when Opium is combined with Trichloroethylene.Experimental
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Opium.Approved
TrifluperidolThe risk or severity of adverse effects can be increased when Opium is combined with Trifluperidol.Experimental
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Opium.Approved, Vet Approved
TrihexyphenidylThe risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Opium.Approved
TrimethaphanThe risk or severity of adverse effects can be increased when Trimethaphan is combined with Opium.Approved
TrimipramineThe risk or severity of adverse effects can be increased when Opium is combined with Trimipramine.Approved
TriprolidineThe risk or severity of adverse effects can be increased when Opium is combined with Triprolidine.Approved
TropatepineThe risk or severity of adverse effects can be increased when Tropatepine is combined with Opium.Experimental
TropicamideThe risk or severity of adverse effects can be increased when Tropicamide is combined with Opium.Approved
TrospiumThe risk or severity of adverse effects can be increased when Trospium is combined with Opium.Approved
TubocurarineThe risk or severity of adverse effects can be increased when Tubocurarine is combined with Opium.Approved
UlaritideThe risk or severity of adverse effects can be increased when Opium is combined with Ularitide.Investigational
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Opium.Approved, Investigational
VecuroniumThe risk or severity of adverse effects can be increased when Vecuronium is combined with Opium.Approved
VenlafaxineOpium may increase the serotonergic activities of Venlafaxine.Approved
VeraliprideThe risk or severity of adverse effects can be increased when Opium is combined with Veralipride.Experimental
VigabatrinThe risk or severity of adverse effects can be increased when Opium is combined with Vigabatrin.Approved
Vinyl etherThe risk or severity of adverse effects can be increased when Opium is combined with Vinyl ether.Experimental
VortioxetineThe risk or severity of adverse effects can be increased when Vortioxetine is combined with Opium.Approved
XenonThe risk or severity of adverse effects can be increased when Opium is combined with Xenon.Experimental
XipamideThe risk or severity of adverse effects can be increased when Opium is combined with Xipamide.Experimental
XylazineThe risk or severity of adverse effects can be increased when Opium is combined with Xylazine.Vet Approved
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Opium.Approved, Illicit, Investigational
ZiconotideThe risk or severity of adverse effects can be increased when Opium is combined with Ziconotide.Approved
ZimelidineOpium may increase the serotonergic activities of Zimelidine.Withdrawn
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with Opium.Approved
ZolazepamThe risk or severity of adverse effects can be increased when Opium is combined with Zolazepam.Vet Approved
ZolpidemOpium may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.Approved
ZonisamideThe risk or severity of adverse effects can be increased when Opium is combined with Zonisamide.Approved, Investigational
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with Opium.Approved
ZotepineThe risk or severity of adverse effects can be increased when Zotepine is combined with Opium.Approved
ZuclopenthixolThe risk or severity of adverse effects can be increased when Zuclopenthixol is combined with Opium.Approved, Investigational
Food Interactions
Not Available

References

General References
Not Available
External Links
Not Available
ATC Codes
N02AA02 — OpiumA07DA02 — Opium
AHFS Codes
  • 56:08.00 — Antidiarrhea Agents
  • 12:08.08 — Antimuscarinics Antispasmodics
  • 84:92.00 — Misc. Skin and Mucous Membrane Agents
  • 28:08.08 — Opiate Agonists

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Not Yet RecruitingTreatmentOpioid Dependence1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
TinctureOral
CapsuleOral
LiquidOral
SuppositoryRectal
TabletOral
TinctureOral200 g
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on December 03, 2015 09:51 / Updated on October 21, 2017 09:34