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Displaying drugs 5376 - 5400 of 11303 in total
Experimental
Matched Iupac: … 5,9b-difluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Experimental
Matched Iupac: … fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Aminorex is an amphetamine-like anorectic agent. It may cause pulmonary hypertension.
Experimental
Illicit
CPG 10101 is a synthetic oligodeoxynucleotide (ODN) in clinical trials. It is a toll-like receptor 9 (TLR9) agonist with antiviral and immunomodulatory properties that could potentially influence chronic infection with HCV.
Investigational
Matched Description: … CPG 10101 is a synthetic oligodeoxynucleotide (ODN) in clinical trials. ... It is a toll-like receptor 9 (TLR9) agonist with antiviral and immunomodulatory properties that could …
HSV-2 theracine is an attenuated recombinant vaccine developed by AuRx for the treatment of genital herpes.
Investigational
Investigational
Amfecloral is a stimulant drug of the phenethylamine and amphetamine chemical classes. For a short period of time, it was available under the brand Acutran and indicated as an appetite suppressant, but this product no longer exists. It acts as a prodrug which splits to form amphetamine and chloral hydrate,...
Experimental
Matched Description: … Amfecloral is a stimulant drug of the phenethylamine and amphetamine chemical classes. ... related compounds, except that the N-substituent, in this case, yields a compound that is active in ... It acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and …
Danofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.
Experimental
Vet approved
Tefibazumab is under investigation in clinical trial NCT00198289 (Aurexis® in Cystic Fibrosis Subjects Chronically Colonized With Staphylococcus Aureus in Their Lungs).
Investigational
ACR-16 is under investigation by NeuroSearch. ACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled trial in patients with Huntington’s disease as well as in three Phase Ib studies within Huntington’s disease, Parkinson’s disease and schizophrenia respectively. ACR-16 is a dopamine stabilizer. ACR-16 is also being...
Investigational
Matched Description: … ACR-16 is a dopamine stabilizer. ... ACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled …
ALS-08 is a proprietary creatine-derivative that is being developed as a potential therapeutic for amyotrophic lateral sclerosis (ALS). It is being developed by Avicena Group, Inc.
Investigational
Matched Description: … ALS-08 is a proprietary creatine-derivative that is being developed as a potential therapeutic for amyotrophic …
AI-128 is the first human demonstration of sustained release drug administration in the lung. AI-128 consists of slowly dissolving microspheres designed to control where drug particles go in the lung and how quickly they release their drug.
Investigational
AV-101 has been used in trials studying the treatment of Neuropathic Pain.
Investigational
AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
Investigational
Investigational
Investigational
Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval. It was sold under the tradename...
Withdrawn
Matched Description: … While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due …
Investigational
Investigational
Tengonermin, also known as NGR-hTNF, is a vascular-targeting drug. It is a recombinant protein and peptide-targeted agent consisting of the human Tumour Necrosis Factor-α (TNF-α) conjugated with the CNGRCG peptide. This drug works by modifying the tumor microenvironment and increasing intratumoral chemotherapy penetration and T-cell infiltration. NGR-hTNF specifically targets angiogenic...
Investigational
Matched Description: … Tengonermin, also known as NGR-hTNF, is a vascular-targeting drug. ... [A233265] It is a recombinant protein and peptide-targeted agent consisting of the human Tumour Necrosis ... [A233270] A study also demonstrated that binding of the NGR-motif to CD13 determined both the homing …
Experimental
AT2220 is an experimental, oral therapy for the treatment of Pompe disease and belongs to a class of molecules known as pharmacological chaperones. It is a small molecule designed to act as a pharmacological chaperone that specifically binds, stabilizes, and facilitates the proper folding and trafficking of α-glucosidase (GAA). GAA...
Investigational
Matched Description: … It is a small molecule designed to act as a pharmacological chaperone that specifically binds, stabilizes ... AT2220 is an experimental, oral therapy for the treatment of Pompe disease and belongs to a class of …
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Investigational
Displaying drugs 5376 - 5400 of 11303 in total