Displaying drugs 651 - 675 of 845 in total
Avidin
Avidin is under investigation in clinical trial NCT00345618 (Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach).
Investigational
Matched Description: … Avidin is under investigation in clinical trial NCT00345618 (Clinical Study Assessing Idrabiotaparinux Sodium …
JZP-386 free base
JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.
Investigational
Matched Description: … JZP-386 is a deuterium-containing analog of sodium oxybate. …
VCA-894A
VCA-894A is a synthetic 2'-O-methoxyethyl phosphorothioate oligoribonucleotide sodium salt consisting of 19 nucleotide residues with the sequence 5'-MeCMeUGMeUGGAAGMeUGAGGGMeCMeCAG-3'
Investigational
Matched Description: … VCA-894A is a synthetic 2'-O-methoxyethyl phosphorothioate oligoribonucleotide sodium salt consisting …
CHF5633
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Description: … preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium …
Aprindine
Aprindine is a cardiac depressant used in arrhythmias.
Experimental
Matched Categories: … Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Tofogliflozin
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Remogliflozin etabonate
Remogliflozin etabonate has been used in trials studying the treatment and basic science of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2.
Investigational
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Epitizide
Epitizide is an agent, commonly found in combination triamterene, used to produce diuresis.
Experimental
Matched Categories: … Sodium Chloride Symporter Inhibitors …
Mersalyl
Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. The sodium salt of a mercury-containing derivative of salicylamide, was formerly...
Experimental
Matched Description: … Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... The sodium salt of a mercury-containing derivative of salicylamide, was formerly used (often in combination …
Matched Salts name: … Mersalyl sodium …
Matched Salts name: … Mersalyl sodium …
Cariporide
Investigational
Luseogliflozin
Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
Investigational
Matched Categories: … Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Ethoxzolamide
Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypokalemia.
Withdrawn
Matched Description: … It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium …
Ularitide
Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Description: … human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium ... When injected into the blood, ularitide appears to cause diuresis (urine output) and natriuresis (sodium …
Edetate copper disodium
Experimental
ALGRX 1207
ALGRX 1207 is a topical local anesthetic that acts by binding to the fast sodium channel. ALGRX 1207 entered clinical trials for cutaneous neuropathic pain, such as chemotherapy-induced neuropathy, in 2006. It was being developed by Anesiva, but trials have halted.
Investigational
Matched Description: … ALGRX 1207 is a topical local anesthetic that acts by binding to the fast sodium channel. …
Methyclothiazide
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Withdrawn
Matched Categories: … Sodium Chloride Symporter Inhibitors …
Pilsicainide
Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
Investigational
Matched Categories: … Sodium Channel Blockers …
Glycochenodeoxycholic Acid
A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. [PubChem]
Experimental
Matched Description: … A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. …
Paramethasone
A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia,...
Experimental
Matched Description: … in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining …
Saprisartan
Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism .
Experimental
Potassium bitartrate
Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as...
Experimental
Azosemide
Azosemide is a loop diuretic used to treat hypertension, edema, and ascites.
Investigational
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors …
SPL84-23-1
SPL84-23-1 is a sodium salt of 19-bp single-stranded RNA uniformly modified 2'-O-(2-methoxyethyl) phosphorothioate Antisense Oligonucleotide (ASO) consisting of 19 nucleotide residues with the sequence 5'-5MeC-5MeU-G-5MeC-A-A-5MeC-A-G-A-5MeU-G-G-A-A-G-A-5MeC-5MeU-3'
Investigational
Matched Description: … SPL84-23-1 is a sodium salt of 19-bp single-stranded RNA uniformly modified 2'-O-(2-methoxyethyl) phosphorothioate …
Istaroxime
Investigational
Matched Categories: … Sodium-Potassium-Exchanging ATPase, antagonists & inhibitors …
Displaying drugs 651 - 675 of 845 in total