Displaying drugs 51 - 75 of 15290 in total
Methohexital
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... 5-Allyl-1-methyl-5-(1-methyl-pent-2-ynyl)-pyrimidine-2,4,6-trione ... 5-allyl-1-methyl-5-(1-methyl-2-pentynyl)-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Hypnotics and Sedatives …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Hypnotics and Sedatives …
Thioridazine
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Synonyms: … 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine ... 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine ... 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine …
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Alectinib
Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Promazine
A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Approved
Vet approved
Matched Synonyms: … N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine …
Matched Iupac: … dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine …
Matched Description: … It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine …
Matched Description: … It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Naratriptan
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Synonyms: … N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide ... N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Amylocaine
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Synonyms: … 1-(Dimethylamino)-2-methyl-2-butanol benzoate …
Matched Description: … and prilocaine in the 1940s and 1950s superseded and made the use of amylocaine obsolete. ... and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute [L1882]. ... clinical use of newer, more effective, and even safer local anesthetics like lidocaine, bupivicaine, …
Matched Description: … and prilocaine in the 1940s and 1950s superseded and made the use of amylocaine obsolete. ... and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute [L1882]. ... clinical use of newer, more effective, and even safer local anesthetics like lidocaine, bupivicaine, …
Propylene glycol
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Approved
Investigational
Matched Synonyms: … methyl glycol …
Matched Description: … A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. …
Matched Mixtures name: … Systane Day and Night Value Pack ... Systane Day and Night Value Pack ... Foster and Thrive Long Lasting Lubricant Eye Drops …
Matched Products: … Eyelash and Eyebrow Lengthener …
Matched Description: … A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. …
Matched Mixtures name: … Systane Day and Night Value Pack ... Systane Day and Night Value Pack ... Foster and Thrive Long Lasting Lubricant Eye Drops …
Matched Products: … Eyelash and Eyebrow Lengthener …
Artemether
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Synonyms: … methyl-dihydroartemisinine ... Dihydroqinghaosu methyl ether ... Artemisininelactol methyl ether …
Matched Description: … and may be used to treat infections caused by P. falciparum and unidentified Plasmodium …
Matched Categories: … Artemisinin and derivatives ... artemether and lumefantrine ... Antiparasitic Products, Insecticides and Repellents …
Matched Description: … and may be used to treat infections caused by P. falciparum and unidentified Plasmodium …
Matched Categories: … Artemisinin and derivatives ... artemether and lumefantrine ... Antiparasitic Products, Insecticides and Repellents …
Zavegepant
Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways. CGRP receptors are expressed in the central and peripheral nervous system; however, CGRP does not cross the...
Approved
Investigational
Matched Synonyms: … 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl ... )-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)- …
Matched Iupac: … N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 …
Matched Description: … [L45505] CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties ... oral zavegepant in migraine prevention, and another one (NCT04987944) is evaluating the safety and efficacy ... other drugs such as [rimegepant] and [ubrogepant]. …
Matched Iupac: … N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 …
Matched Description: … [L45505] CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties ... oral zavegepant in migraine prevention, and another one (NCT04987944) is evaluating the safety and efficacy ... other drugs such as [rimegepant] and [ubrogepant]. …
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … 2-naphthacenecarboxamido)methyl)lysine ... N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline ... carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl …
Matched Iupac: … ,5,5a,6,11,12a-octahydrotetracen-2-yl]formamido}methyl)amino]-2-aminohexanoic acid ... (2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …
Matched Iupac: … ,5,5a,6,11,12a-octahydrotetracen-2-yl]formamido}methyl)amino]-2-aminohexanoic acid ... (2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …
Iodoform
Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions . Due to its antimicrobial properties following topical administration, minimal levels of iodoform may be found in disinfectants and it is more...
Approved
Experimental
Vet approved
Matched Synonyms: … methyl triiodide …
Matched Description: … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. ... dressing or powder for wounds and sores, however such clinical use to this date is limited. ... Since the beginning of the 20th century, iodoform has been commonly used as a healing and antiseptic …
Matched Description: … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. ... dressing or powder for wounds and sores, however such clinical use to this date is limited. ... Since the beginning of the 20th century, iodoform has been commonly used as a healing and antiseptic …
Methylchloroisothiazolinone
Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. It is found within many commercially available cosmetics, lotions, and makeup removers. It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness,...
Approved
Experimental
Matched Synonyms: … 5-Chloro-2-methyl-3(2H)-isothiazolone ... 4-Isothiazolin-3-one, 5-chloro-2-methyl- …
Matched Iupac: … 5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one …
Matched Description: … It is found within many commercially available cosmetics, lotions, and makeup removers. ... scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area. ... Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and …
Matched Iupac: … 5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one …
Matched Description: … It is found within many commercially available cosmetics, lotions, and makeup removers. ... scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area. ... Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and …
Zolmitriptan
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Synonyms: … 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one ... (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … It is currently available in both tablet and nasal spray forms.[L12978] ... A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and ... [A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … It is currently available in both tablet and nasal spray forms.[L12978] ... A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and ... [A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Trimethobenzamide
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Synonyms: … N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide …
Matched Iupac: … N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4,5-trimethoxybenzamide …
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Matched Iupac: … N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4,5-trimethoxybenzamide …
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Fluoxymesterone
An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Synonyms: … 17α-Methyl-9α-fluoro-11β-hydroxytesterone ... 11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androster-3-one …
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Buprenorphine
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2 ... hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl …
Matched Description: … who require larger and more frequent doses. ... an improved safety profile with a lower risk of overdose and respiratory depression. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist …
Matched Mixtures name: … Buprenorphine and Naloxone ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …
Matched Description: … who require larger and more frequent doses. ... an improved safety profile with a lower risk of overdose and respiratory depression. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist …
Matched Mixtures name: … Buprenorphine and Naloxone ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …
Hypromellose
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Synonyms: … Cellulose hydroxypropyl methyl ether ... Cellulose, 2-hydroxypropyl methyl ether …
Matched Description: … binder in the process of granulation and in modified release formulations [A24840]. ... Hypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic ... acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and …
Matched Mixtures name: … Rohto Sun and Sport …
Matched Description: … binder in the process of granulation and in modified release formulations [A24840]. ... Hypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic ... acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and …
Matched Mixtures name: … Rohto Sun and Sport …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine ... (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine ... (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine …
Matched Iupac: … (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... lansoprazole, amoxicillin and levofloxacin ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... lansoprazole, amoxicillin and levofloxacin ... Metabolic Side Effects of Drugs and Substances …
Sodium tetradecyl sulfate
An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched Synonyms: … Sodium 2-methyl-7-ethylundecanol-4-sulfate ... 7-Ethyl-2-methyl-4-undecanol sulfate sodium salt ... Sodium 7-ethyl-2-methyl-4-undecanol sulfate …
Matched Description: … irritant and sclerosing agent for hemorrhoids and varicose veins. ... An anionic surface-active agent used for its wetting properties in industry and used in medicine as an …
Matched Description: … irritant and sclerosing agent for hemorrhoids and varicose veins. ... An anionic surface-active agent used for its wetting properties in industry and used in medicine as an …
Mycophenolate mofetil
Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Synonyms: … 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate …
Matched Iupac: … 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex …
Matched Description: … to prevent organ rejection after hepatic, renal, and cardiac transplants. ... Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified ... [A180805] This drug is an immunosuppressant combined with drugs such as [Cyclosporine] and corticosteroids …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Matched Iupac: … 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex …
Matched Description: … to prevent organ rejection after hepatic, renal, and cardiac transplants. ... Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified ... [A180805] This drug is an immunosuppressant combined with drugs such as [Cyclosporine] and corticosteroids …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Benoxaprofen
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(p-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(4-Chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Rosiglitazone
Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched Synonyms: … (±)-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione ... (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion …
Matched Iupac: … 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione …
Matched Description: … Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone …
Matched Iupac: … 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione …
Matched Description: … Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone …
Clidinium
Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also...
Approved
Matched Synonyms: … N-methyl quinuclidinyl benzilate ... 3-(2-Hydroxy-2,2-diphenyl-acetoxy)-1-methyl-1-azonia-bicyclo[2.2.2]octane …
Matched Iupac: … (1s,4s)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. ... or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome. ... Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies …
Matched Mixtures name: … Chlordiazepoxide Hydrochloride and Clidinium Bromide ... Chlordiazepoxide HCl and Clidinium Bromide ... Chlordiazepoxide Hydrochloride and Clidinium Bromide …
Matched Categories: … Alimentary Tract and Metabolism ... clidinium and psycholeptics …
Matched Iupac: … (1s,4s)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. ... or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome. ... Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies …
Matched Mixtures name: … Chlordiazepoxide Hydrochloride and Clidinium Bromide ... Chlordiazepoxide HCl and Clidinium Bromide ... Chlordiazepoxide Hydrochloride and Clidinium Bromide …
Matched Categories: … Alimentary Tract and Metabolism ... clidinium and psycholeptics …
Sumatriptan
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Synonyms: … 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide ... 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide …
Matched Description: … [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available ... Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … sumatriptan and naproxen ... Genito Urinary System and Sex Hormones ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Description: … [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available ... Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … sumatriptan and naproxen ... Genito Urinary System and Sex Hormones ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Tipiracil
Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been...
Approved
Investigational
Matched Synonyms: … 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione ... 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … metastatic colorectal cancer which has been previously treated with fluoropyrimidine-, oxaliplatin- and …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … metastatic colorectal cancer which has been previously treated with fluoropyrimidine-, oxaliplatin- and …
Displaying drugs 51 - 75 of 15290 in total