Displaying drugs 1001 - 1025 of 1083 in total
Isoliquiritigenin
Isoliquiritigenin is a precursor to several flavonones in many plants.
Experimental
Matched Synonyms: … (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propene-1-one …
MALP-2
Investigational
Matched Synonyms: … L-lysine, s-((2r)-2,3-bis((1-oxohexadecyl)oxy)propyl)-l-cysteinylglycyl-l-asparaginyl-l-asparaginyl-l …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). ... as amitriptyline and clomipramine. …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Desipramine Hydrochloride …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Desipramine Hydrochloride …
Edetic acid
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine) …
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition …
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition …
3-(4-hydroxy-3-imino-6-oxo-cyclohexa-1,4-dienyl)-alanine
Experimental
Matched Name: … 3-(4-hydroxy-3-imino-6-oxo-cyclohexa-1,4-dienyl)-alanine …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … -{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Tyrosine Kinase Inhibitors ... ROS1 tyrosine kinase inhibitors ... Receptor Protein-Tyrosine Kinases, antagonists & inhibitors …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Tyrosine Kinase Inhibitors ... ROS1 tyrosine kinase inhibitors ... Receptor Protein-Tyrosine Kinases, antagonists & inhibitors …
Valproic acid
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... [L6190]
Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects …
Matched Products: … VALKENE ... VALOIN INJECTION …
Matched Products: … VALKENE ... VALOIN INJECTION …
2,2-bis(4-hydroxy-3-tert-butylphenyl)propane
TBD has been used in trials studying the treatment of Adenocarcinoma.
Investigational
Matched Name: … 2,2-bis(4-hydroxy-3-tert-butylphenyl)propane …
3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol
Experimental
Matched Name: … 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol …
Caspofungin
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Synonyms: … hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline …
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester …
Celecoxib
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched International brands: … Valdyne …
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... tramadol and celecoxib ... amlodipine and celecoxib …
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... tramadol and celecoxib ... amlodipine and celecoxib …
Buprenorphine
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … an improved safety profile with a lower risk of overdose and respiratory depression. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... who require larger and more frequent doses. …
Matched Mixtures name: … Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate …
Matched Salts name: … Buprenorphine hydrochloride …
Matched Products: … Buprenorphine Hydrochloride ... Buprenorphine hydrochloride ... Buprenorphine Hydrochloride Sublingual …
Matched Mixtures name: … Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate …
Matched Salts name: … Buprenorphine hydrochloride …
Matched Products: … Buprenorphine Hydrochloride ... Buprenorphine hydrochloride ... Buprenorphine Hydrochloride Sublingual …
3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene
Experimental
Matched Name: … 3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene …
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE …
(3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine
Experimental
Matched Name: … (3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine …
Ziprasidone
Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Description: … Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior ... abuse, and can significantly impact the quality of life of patients and caregivers. ... [A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to …
Matched Salts name: … Ziprasidone hydrochloride …
Matched Categories: … Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Ziprasidone Hydrochloride ... Ziprasidone hydrochloride …
Matched Salts name: … Ziprasidone hydrochloride …
Matched Categories: … Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Ziprasidone Hydrochloride ... Ziprasidone hydrochloride …
Anagrelide
Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in the US in 1997. It appears to carry a better response rate than other thrombocythemia treatments (e.g....
Approved
Matched Description: … [busulfan], [hydroxyurea]) and may be better tolerated.[A214274] …
Matched Salts name: … Anagrelide hydrochloride ... Anagrelide hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Anagrelide Hydrochloride …
Matched Salts name: … Anagrelide hydrochloride ... Anagrelide hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Anagrelide Hydrochloride …
1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane
Experimental
Matched Name: … 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane …
N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Experimental
Matched Name: … N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine …
Nerinetide
Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling Therapy).
Investigational
Matched Synonyms: … -ASPARTYL-L-VALINE ... L-VALINE, L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Fluoxetine
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Description: … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Salts name: … Fluoxetine hydrochloride …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ANDEP ... Fluoxetine Hydrochloride ... Fluoxetine hydrochloride …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Salts name: … Fluoxetine hydrochloride …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ANDEP ... Fluoxetine Hydrochloride ... Fluoxetine hydrochloride …
N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE
Experimental
Matched Name: … N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE …
Prenylamine
Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Approved
Withdrawn
Matched Synonyms: … 1-Phenyl-2-(1',1'-diphenylpropyl-3'-amino)propane …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents …
ABBV-CLS-7262
Investigational
Matched Synonyms: … fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen phosphate - 2-amino-2- (hydroxymethyl)propane …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Displaying drugs 1001 - 1025 of 1083 in total