Displaying all 8 drugs
Hepatitis B Vaccine (Recombinant)
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada.
The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Synonyms: … Hepatitis B virus hbsag surface protein antigen ... Hepatitis B surface antigen ... Hepatitis-B surface antigen …
Matched Name: … Hepatitis B Vaccine (Recombinant) …
Matched Description: … It is estimated that the reservoir of persistent hepatitis B surface antigen carriers amounts to 350 ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. ... Hepatitis D virus, a defective virus requiring the “keeper function” of the hepatitis B virus, occurs …
Matched Salts name: … Hepatitis B virus subtype ADW HBSAG surface protein antigen ... Hepatitis B virus subtype ADW2 HBSAG surface protein antigen …
Matched Categories: … Inactivated Hepatitis B Virus Vaccine ... Hepatitis B Surface Antigens ... Hepatitis B Surface Antigens, drug effects ... haemophilus influenzae B and hepatitis B ... Hepatitis B Antigens …
Matched Products: … VAKSIN HEPATITIS B REKOMBINAN ... VACUNADE LA HEPATITIS B (RADN) ... SII Hepatitis-B Vaccine (rDNA)(Adult)-Single Dose 1ml …
Matched Name: … Hepatitis B Vaccine (Recombinant) …
Matched Description: … It is estimated that the reservoir of persistent hepatitis B surface antigen carriers amounts to 350 ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. ... Hepatitis D virus, a defective virus requiring the “keeper function” of the hepatitis B virus, occurs …
Matched Salts name: … Hepatitis B virus subtype ADW HBSAG surface protein antigen ... Hepatitis B virus subtype ADW2 HBSAG surface protein antigen …
Matched Categories: … Inactivated Hepatitis B Virus Vaccine ... Hepatitis B Surface Antigens ... Hepatitis B Surface Antigens, drug effects ... haemophilus influenzae B and hepatitis B ... Hepatitis B Antigens …
Matched Products: … VAKSIN HEPATITIS B REKOMBINAN ... VACUNADE LA HEPATITIS B (RADN) ... SII Hepatitis-B Vaccine (rDNA)(Adult)-Single Dose 1ml …
Hepatitis A Vaccine
Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely...
Approved
Matched Synonyms: … Hepatitis A vaccine, inactivated …
Matched Name: … Hepatitis A Vaccine …
Matched Description: … formulated for immunization against hepatitis A virus (HAV) infection and safely confers strong protection ... [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently ... Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms …
Matched Salts name: … Hepatitis A virus strain HM175 antigen (formaldehyde inactivated) ... Hepatitis A virus strain CR 326F antigen (formaldehyde inactivated) …
Matched Categories: … Inactivated Hepatitis A Virus Vaccine ... Viral Hepatitis Vaccines …
Matched Products: … VAQTA ® 50 U VACUNA CONTRA LA HEPATITIS A (PURIFICADA E INACTIVADA) ... Havrix (Hepatitis A-Impfstoff) 1440 El.U/ml - Injektionssuspension in einer Fertigspritze ... Havrix (Hepatitis A-Impfstoff) Junior 720 El.U/0,5 ml - Injektionssuspension in einer Fertigspritze …
Matched Name: … Hepatitis A Vaccine …
Matched Description: … formulated for immunization against hepatitis A virus (HAV) infection and safely confers strong protection ... [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently ... Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms …
Matched Salts name: … Hepatitis A virus strain HM175 antigen (formaldehyde inactivated) ... Hepatitis A virus strain CR 326F antigen (formaldehyde inactivated) …
Matched Categories: … Inactivated Hepatitis A Virus Vaccine ... Viral Hepatitis Vaccines …
Matched Products: … VAQTA ® 50 U VACUNA CONTRA LA HEPATITIS A (PURIFICADA E INACTIVADA) ... Havrix (Hepatitis A-Impfstoff) 1440 El.U/ml - Injektionssuspension in einer Fertigspritze ... Havrix (Hepatitis A-Impfstoff) Junior 720 El.U/0,5 ml - Injektionssuspension in einer Fertigspritze …
Simeprevir
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Iupac: … (1R,4R,6R,7Z,15R,17R)-N-(cyclopropanesulfonyl)-17-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol ... -2-yl]quinolin-4-yl}oxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.0^{4,6}]octadec-7-ene-4-carboxamide …
Matched Description: … Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype ... antiviral agent against the hepatitis C virus. ... 1 for the treatment of chronic hepatitis C virus (HCV) infection. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADET …
Matched Description: … Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype ... antiviral agent against the hepatitis C virus. ... 1 for the treatment of chronic hepatitis C virus (HCV) infection. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADET …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea ... 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated ... in tumour cell proliferation and tumour angiogenesis. …
Matched Categories: … Protein Kinase Inhibitors ... Antineoplastic and Immunomodulating Agents ... UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated ... in tumour cell proliferation and tumour angiogenesis. …
Matched Categories: … Protein Kinase Inhibitors ... Antineoplastic and Immunomodulating Agents ... UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Glecaprevir
Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor that targets the the viral RNA replication. In combination with DB13878, glecaprevir is a useful therapy for patients who experienced therapeutic failure from other NS3/4A protease inhibitors. It demonstrates a high genetic barrier against resistance...
Approved
Investigational
Matched Iupac: … (1R,14E,18R,22R,26S,29S)-26-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl ... 4,11,25,28-tetraazapentacyclo[26.2.1.0^{3,12}.0^{5,10}.0^{18,22}]hentriaconta-3,5(10),6,8,11,14-hexaene-29 …
Matched Description: … Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor ... It demonstrates a high genetic barrier against resistance mutations of the virus. ... Hepatitis C viral infection often leads to decreased liver function and subsequent liver failure, causing …
Matched Categories: … Treatments for Hepatitis C ... Heterocyclic Compounds, 2-Ring ... glecaprevir and pibrentasvir ... Amino Acids, Peptides, and Proteins …
Matched Description: … Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor ... It demonstrates a high genetic barrier against resistance mutations of the virus. ... Hepatitis C viral infection often leads to decreased liver function and subsequent liver failure, causing …
Matched Categories: … Treatments for Hepatitis C ... Heterocyclic Compounds, 2-Ring ... glecaprevir and pibrentasvir ... Amino Acids, Peptides, and Proteins …
TMC-647055
TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, and Chronic Hepatitis C Virus.
Investigational
Matched Iupac: … }.1^{3,26}.0^{20,25}]nonacosa-2(29),3,5,18,20,22,24,26(28)-octaene-7,9,9,17-tetrone ... 28-cyclohexyl-22-methoxy-10,16-dimethyl-13-oxa-9lambda6-thia-1,8,10,16-tetraazapentacyclo[16.8.1.1^{2,6 …
Matched Description: … C, Chronic, and Chronic Hepatitis C Virus. ... TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis …
Matched Description: … C, Chronic, and Chronic Hepatitis C Virus. ... TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis …
MK-2748
MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)).
Investigational
Matched Iupac: … (1R,18R,22R,26S,29S)-26-cyclopentyl-N-[(1R,2S)-2-ethenyl-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl} ... -4,12,25,28-tetraazapentacyclo[26.2.1.0^{3,12}.0^{5,10}.0^{18,22}]hentriaconta-3,5(10),6,8-tetraene-29 …
Matched Description: … and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)). ... MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety …
Matched Description: … and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)). ... MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety …
Displaying all 8 drugs