Pharmacological, therapeutic and toxicological properties of furazolidone: some recent research.
Article Details
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Ali BH
Pharmacological, therapeutic and toxicological properties of furazolidone: some recent research.
Vet Res Commun. 1999 Oct;23(6):343-60.
- PubMed ID
- 10543364 [ View in PubMed]
- Abstract
Some of the recent publications on the pharmacological, therapeutic and toxicological properties of the antimicrobial agent furazolidone (FZ) are briefly reviewed. In animals, most of the recently published papers focus on (1) the methodology of measuring the residues of the drug and its metabolites in edible tissues; (2) the carcinogenicity and genotoxicity of FZ; (3) the cellular and molecular basis of FZ-induced cardiomyopthy, and the action of different cardioprotectant drugs thereon; and (4) hormonal effects. In humans, the use of FZ as an anti-ulcer drug and in controlling infectious diseases, especially opportunistic infections in AIDS patients, is described.
DrugBank Data that Cites this Article
- Drug Enzymes
Drug Enzyme Kind Organism Pharmacological Action Actions Furazolidone Amine oxidase [flavin-containing] A Protein Humans UnknownInhibitorDetails Furazolidone Amine oxidase [flavin-containing] B Protein Humans UnknownInhibitorDetails