In vitro antibacterial activity of cefpiramide.
Article Details
- CitationCopy to clipboard
Pfaller MA, Niles AC, Murray PR
In vitro antibacterial activity of cefpiramide.
Antimicrob Agents Chemother. 1984 Mar;25(3):368-72.
- PubMed ID
- 6426381 [ View in PubMed]
- Abstract
A microbroth dilution method was used to measure the MICs of cefpiramide (SM 1652), cefotaxime, moxalactam, ceftazidime, cefoperazone, ceftriaxone, piperacillin, and mezlocillin against 921 isolates of gram-negative (701) and gram-positive (220) bacteria. The activity of cefpiramide was equivalent to those of piperacillin and mezlocillin against members of the family Enterobacteriaceae and gram-positive isolates, including enterococci. Cefpiramide had equivalent or slightly greater activity against Pseudomonas aeruginosa than the other beta-lactam antibiotics tested.
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Cefpiramide D-alanyl-D-alanine carboxypeptidase DacC Protein Escherichia coli (strain K12) YesInhibitorDetails Cefpiramide Penicillin-binding protein 1A Protein Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) YesInhibitorDetails Cefpiramide Penicillin-binding protein 1A Protein Escherichia coli (strain K12) YesInhibitorDetails Cefpiramide Penicillin-binding protein 1B Protein Pseudomonas aeruginosa YesInhibitorDetails