The presence of free D-serine, D-alanine and D-proline in human plasma.

Article Details

Citation

Nagata Y, Masui R, Akino T

The presence of free D-serine, D-alanine and D-proline in human plasma.

Experientia. 1992 Oct 15;48(10):986-8.

PubMed ID
1426150 [ View in PubMed
]
Abstract

Twelve neutral free amino acids, i.e. serine, threonine, glutamine, asparagine, alanine, proline, methionine, tyrosine, valine, leucine, isoleucine and phenylalanine, were surveyed for the presence of D-enantiomers in plasma samples from patients with renal diseases and from normal subjects. D-serine, D-alanine and D-proline were found in the patient's plasma. The highest concentrations (D/L ratio) of D-serine, D-alanine and D-proline were 0.2362, 0.2087 and 0.0986, respectively. The sum of the contents of the three D-amino acid was shown to be present in the plasma proteins.

DrugBank Data that Cites this Article

Drugs