Fatal accidental enflurane intoxication.

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Jacob B, Heller C, Daldrup T, Burrig KF, Barz J, Bonte W

Fatal accidental enflurane intoxication.

J Forensic Sci. 1989 Nov;34(6):1408-12.

PubMed ID
2584946 [ View in PubMed
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Abstract

Among reported cases of abuse of volatile anesthetics there is only one of enflurane intoxication. We report another fatal enflurane intoxication. A 21-year-old man found dead seemed to have experimented with enflurane. Three and one-half days after death high amounts of enflurane were detected in blood, brain, and subcutaneous fat. Gas chromatographic quantification revealed the following high enflurane concentrations: blood: 130 mg/l-1, brain: 350 mg/l-1, and subcutaneous fat: 100 mg/l-1. Histologic signs of drug-induced damage were lacking. No suicide intentions became known. It was concluded that the young man died of an accidental intoxication while abusing enflurane.

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