Posaconazole.

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Bhattacharya M, Rajeshwari K, Dhingra B

Posaconazole.

J Postgrad Med. 2010 Apr-Jun;56(2):163-7. doi: 10.4103/0022-3859.65281.

PubMed ID

20622401 [ View in PubMed

]

Abstract

Posaconazole is a novel second-generation Triazole oral antifungal agent. It is highly effective in the prophylaxis of invasive fungal infections in immunocompromised patients. It is used as a first-line agent as well as for salvage therapy in invasive fungal infections including aspergillosis, oropharyngeal and esophageal candidiasis. It has a good adverse effect profile. With the rising incidence of invasive fungal infections due to the HIV pandemic and medical advancements in transplantation and cancer therapy, these features make posaconazole a valuable addition in the family of antifungal agents.

DrugBank Data that Cites this Article

Drugs

Posaconazole

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Posaconazole	Cytochrome P450 51	Protein	Yeast	Yes	Antagonist	Details