Muscarinic Antagonists

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Naji A, Gatling JW

Muscarinic Antagonists

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PubMed ID

32491473 [ View in PubMed

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Abstract

Muscarinic receptor antagonists (MRAs) are a group of agents that function by competitively blocking the cholinergic response manifested by acetylcholine (ACh) binding muscarinic receptors on exocrine glandular cells, cardiac muscle cells, and smooth muscle cells. Therefore, MRAs are heavily involved with the parasympathetic nervous system and act on different types of muscarinic receptors resulting in a wide array of clinical indications.

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Hyoscyamine