Itraconazole.
Article Details
- CitationCopy to clipboard
Kurn H, Wadhwa R
Itraconazole.
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- PubMed ID
- 32491797 [ View in PubMed]
- Abstract
Itraconazole is a medication used in the management and treatment of fungal infections. It is in the antifungal class of drugs. Many of these fungal infections are rare; however, they can be detrimental to the immunocompromised. Some patient populations that frequently use itraconazole prophylaxis are patients with HIV, those receiving chemotherapy, or people who have had an organ transplant. This activity reviews the indications, mechanism of action, adverse event profile, and contraindications for itraconazole as a valuable agent in treating systemic fungal infections and other disorders, including off-label indications pertinent for healthcare team members in the treatment of patients with systemic fungal infections and related conditions.
DrugBank Data that Cites this Article
- Drugs
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Itraconazole Lanosterol 14-alpha demethylase Protein Candida tropicalis YesInhibitorDetails