Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors.
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Hartman GD, Egbertson MS, Halczenko W, Laswell WL, Duggan ME, Smith RL, Naylor AM, Manno PD, Lynch RJ, Zhang G, et al.
Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors.
J Med Chem. 1992 Nov 27;35(24):4640-2.
- PubMed ID
- 1469694 [ View in PubMed]
- Abstract
Not Available
DrugBank Data that Cites this Article
- Binding Properties
Drug Target Property Measurement pH Temperature (°C) Tirofiban Integrin beta-3 IC 50 (nM) 5 N/A N/A Details Tirofiban Integrin beta-3 IC 50 (nM) 11 N/A N/A Details Tirofiban Integrin beta-3 IC 50 (nM) 260000 N/A N/A Details Tirofiban Integrin beta-3 IC 50 (nM) 100000 N/A N/A Details