Application of the three-dimensional structures of protein target molecules in structure-based drug design.
Article Details
- CitationCopy to clipboard
Greer J, Erickson JW, Baldwin JJ, Varney MD
Application of the three-dimensional structures of protein target molecules in structure-based drug design.
J Med Chem. 1994 Apr 15;37(8):1035-54.
- PubMed ID
- 8164249 [ View in PubMed]
- Abstract
Not Available
DrugBank Data that Cites this Article
- Binding Properties
Drug Target Property Measurement pH Temperature (°C) (4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide Carbonic anhydrase 2 Ki (nM) 1.9 N/A N/A Details Dorzolamide Carbonic anhydrase 2 IC 50 (nM) 1.1 N/A N/A Details Dorzolamide Carbonic anhydrase 2 Ki (nM) 0.37 N/A N/A Details Dorzolamide Carbonic anhydrase 2 IC 50 (nM) 30 N/A N/A Details Dorzolamide Carbonic anhydrase 2 Ki (nM) 15 N/A N/A Details