The unexpected side effects of new nonsteroidal anti-inflammatory drugs.
Article Details
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Uzan A
The unexpected side effects of new nonsteroidal anti-inflammatory drugs.
Expert Opin Emerg Drugs. 2005 Nov;10(4):687-8.
- PubMed ID
- 16262557 [ View in PubMed]
- Abstract
Conventional nonselective NSAIDs are classically associated with a risk of gastrointestinal disorders. These drugs have a broad range of relative selectivity towards the COX family, mainly towards two isoforms of these enzymes: COX-1 and -2. As examples, ketorolac, flurbiprofen, ketoprofen and indomethacin have increased COX-1 selectivity when compared with naproxen and ibuprofen.
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Ketorolac Prostaglandin G/H synthase 1 Protein Humans UnknownInhibitorDetails