Glycopeptide Antibacterials

Name
Glycopeptide Antibacterials
Accession Number
DBCAT002402
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
VancomycinA glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections.
OritavancinAn antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria.
TeicoplaninA glycopeptide antibiotic with a similar mechanism of action and spectrum of activity to vancomycin used to treat various infections caused by gram-positive bacteria.
DalbavancinAn antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria.
TelavancinAn antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia.
Drugs & Drug Targets
DrugTargetType
VancomycinD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
VancomycinSerum albumincarrier
Vancomycinalpha1-acid glycoproteincarrier
VancomycinHistamine H1 receptorcarrier
OritavancinCytochrome P450 3A4enzyme
OritavancinCytochrome P450 2D6enzyme
OritavancinCytochrome P450 2C9enzyme
OritavancinCytochrome P450 2C19enzyme
OritavancinSerum albumincarrier
OritavancinPeptidoglycan precursorstarget
OritavancinBacterial cell wall peptide bridging segmentstarget
OritavancinPentaglycyl bridging segmenttarget
TeicoplaninD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
DalbavancinD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget